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Front Physiol
March 2019
Department of Cold Environment Medicine, College of High Altitude Military Medicine, Third Military Medical University and Key Laboratory of High Altitude Medicine, Ministry of Education, Key Laboratory of High Altitude Medicine, PLA, Chongqing, China.
Central fatigue is defined as a failure of the central nervous system to adequately drive the muscle, manifesting limited development, and maintenance of locomotor activity. A plateau in hypoxia leads to central fatigue and followed by maximal motility recession. However, the underlying mechanism is still unclear.
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