7 results match your criteria: "Theodore Fontane Medical University of Brandenburg[Affiliation]"
Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes-A Putative Contributor to Dry Skin Dermatoses.
J Invest Dermatol
January 2019
Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary. Electronic address:
OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes.
Mech Ageing Dev
June 2018
Department of Dermatology, Medical University of Vienna, Währinger Gürtel 18-20, Leitstelle 7J, A-1090 Vienna, Austria; Christian Doppler Laboratory for Biotechnology of Skin Aging, Austria. Electronic address:
Article Synopsis
- Phospholipid oxidation products (OxPL) are important stress signaling molecules in the skin, influencing its response to aging and oxidative stress.
- OLR1, a receptor found in various skin cells, particularly sebocytes and keratinocytes, was studied to assess its role in the signaling effect of OxPL.
- Results showed that while OLR1 isn't needed for the transcriptional response to oxidized lipids, its knockdown affected genes related to cell growth and movement, highlighting sebocytes' unique reaction to lipid-induced stress.
Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes.
Int J Mol Med
October 2017
Department of Dermatology, Renmin Hospital of Wuhan University, Wuchang, Wuhan, Hubei 430060, P.R. China.
A large body of evidence indicates that particulate matter (PM)2.5 is associated with various negative effects on human health. However, the impact and molecular mechanism of PM2.
View Article and Find Full Text PDFAnti-acne drugs in phase 1 and 2 clinical trials.
Expert Opin Investig Drugs
July 2017
c Department of Venerology and Dermatology , Otto von Guericke University Magdeburg, Magdeburg , Germany.
Despite the impressive increase of knowledge on acne etiology accumulated during the last 20 years, few efforts have been overtaken to introduce new therapeutic regiments targeting the ideal treatment of acne. The increasing emergence of microbial resistance associated with antibiotics, teratogenicity, particularly associated with systemic isotretinoin, and the need for an adverse drug profile, which can be tolerated by the patient, make the need of new pathogenesis relevant anti-acne agents an emerging issue. Areas covered: A search for phase 1 and 2 acne treatment trials in the US National Institutes of Health database of clinical trials and the European Medicines Agency database with the key words 'acne' and 'treatment' was carried out, on 6 January 2017.
View Article and Find Full Text PDFBenign atrophic papulosis (Köhlmeier-Degos disease): the wedge-shaped dermal necrosis can resolve with time.
J Eur Acad Dermatol Venereol
October 2017
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Background: Atrophic papulosis is a rare thrombo-occlusive disease, characterized by the appearance of multiple atrophic porcelain-white skin papules, with a surrounding erythematous rim, which are histologically consisting of wedge-shaped necrosis of the dermis.
Objective: It consists of two variants: (i) the benign atrophic papulosis (BAP) only involving the skin and (ii) the malignant atrophic papulosis (MAP) also involving several internal organs with a cumulative five-year survival rate of approx. 55%.
Small cryotherapy devices for the treatment of skin warts.
J Dermatolog Treat
December 2017
b Departments of Dermatology, Venereology, Allergology and Immunology , Dessau Medical Center, Theodore Fontane Medical University of Brandenburg, Dessau , Germany.
Study Purpose: Effectiveness of cryotherapy on skin wart models.
Materials And Methods: Two small cryotherapy devices, Wartner and Wortie, were administered for 10″-60″ on tomatoes and potatoes used as skin wart models. Frozen surface and depth were evaluated by standardized photography and computer analysis.
The freeze thaw cycle in cryosurgery - Response to Dr. David Buckley.
J Eur Acad Dermatol Venereol
September 2017
Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Theodore Fontane Medical University of Brandenburg, 06847, Dessau, Germany.