Validation of SSR markers for identification of high-yielding and Phytophthora Capsici root rot resistant chilli genotypes.

The study was designed to validate the previously reported 34 SSR markers using 78 chilli genotypes to detect significant trait specific markers as well as superior genotypes resistant to Phytophthora capsici root rot (PcRR). In this context, the identification of germplasm with higher yield per plant (YPP) leads to hype in stress tolerance index (STI) in genotypes, Chakwal3 (11.98), Greenfire (10.

The Complex Relationship Between Chronic Obstructive Pulmonary Disease With Cardiovascular Disease and Their Interactions With COVID-19 Vaccination: A Retrospective Study.

Background: Previously, most researchers explored the association between chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD). This study investigates the distinct influence of COVID-19 vaccination status on patients with both conditions.

Objective: We investigate the relationship between COPD and CVD in a cohort of 838 individuals who presented with both conditions.

Putting forward novel sulfonamide-thiazole-pyrazoline hybrids as potential central core structure for the development of non-specific b-TNAP and c-IAP inhibitors.

Alkaline phosphatases (ALPs) play crucial role in various functions of human body, such as bone formation, metabolism in liver and intestines, and transfer of nutrients from mother to fetus during pregnancy. However, their overexpression is associated with severe consequences in different patients, such as deposition of minerals in dialysis patients also called coronary calcification and increased bone turnover in patients facing cancer metastization. Due to their involvement in crucial functions of human body and association with such harsh consequences, there is need of newer efficient ALP inhibitors that can tackle ALP excess without derailing the progress of normal functions.

Conservation agriculture effects on ecosystem health and sustainability - A review of rice-wheat cropping system.

Conventional tillage, extreme climate events, increasing weed incidence, pest and disease pressures, and diminished farm input availability negatively impact crop yield, stability, profitability, and water productivity in South Asia's rice-wheat (R-W) systems. This article reviews and evaluates the effectiveness and benefits of conservation agriculture (CA) practices in improving soil health, water productivity, and sustainability in R-W systems. CA practices focus on minimum soil disturbance, permanent soil cover, and crop rotations.

Does Despotic Leadership Impact Employees' Career success: The Parallel Mediation Framework.

Drawing on the conservation of resource (COR) theory principles, this study demonstrates how despotic leadership (DL) negatively impacts employee career success (ECS) in the pharmaceutical industry. Since this is a serious growing concern in emerging research and a threat to the career therefore we aimed to investigate the relationship between (DL) and (ECS). Parallel mediating effects of job insecurity (JI) and emotional exhaustion (EE) are also tested which was overlooked in previous literature.

Unleashing the synergistic effect of promising fungicides: a breakthrough solution for combating powdery mildew in pea plants.

Pea powdery mildew, caused by , is a major limitation to global pea production. The emergence of fungicide-resistant pathogen populations due to frequent and injudicious pesticide application highlights the importance of exploring the synergistic properties of fungicide combinations. This study investigated the efficacy of difenoconazole, thiophanate-methyl, and sulfur, both individually and in mixtures, against powdery mildew and assessed the interaction types between these fungicides.

Welfare assessment of dromedary camels kept under pastoralism in Pakistan.

Standardized welfare assessment protocols are crucial to enhance animal welfare; up to date, there is no data on the level of welfare of camels kept under pastoralism. A tailored protocol for measuring welfare in dromedary camels kept under nomadic pastoralist conditions was recently developed, drawing from the currently available welfare protocol for dromedary camels kept in intensive systems. This study, therefore, aimed to apply the newly developed tailored protocol and assess the welfare of dromedary camels kept under pastoralism in the Southern Punjab Province of Pakistan.

Antioxidant and renal protective effects of Nano-selenium on adenine-induced acute renal failure in canines.

Acute renal failure is a common clinical disease in canines, affecting antioxidant levels and decreasing the body's resistance. This study aims to explore the therapeutic mechanism of Nano-selenium in acute renal failure. The histopathological and imaging changes of kidney tissue were observed with the gene and protein expression levels of Keap1, Nrf2, HO-1, and NQO1 in the kidney.

Associations between and polymorphisms and thalassemia risk.

Objectives: This study investigated the associations of the rs4671393, rs1427407, and rs11886868 genetic variants of the gene and the rs9399137 variant of the gene with thalassemia in patients from the population of Punjab, Pakistan.

Methods: A cohort of 600 participants, comprising 300 patients with thalassemia and 300 age- and sex-matched healthy controls, was recruited from various hospitals in Punjab, Pakistan. DNA was extracted from whole blood samples from all participants.

Nutritional composition, bioactive compounds and antioxidant potentiality of some indigenous vegetables consumed in Bangladesh.

Food and nutrition security are essential for accomplishing sustainable development goals, and a growing population requires various food sources to address hunger and nutrition. Indigenous vegetables are nutritious, healthy, and adaptable to local conditions, making them a potential food and nutrition security resource. Thus, this study aimed to evaluate the nutritional richness of indigenous vegetables by comparing the nutritional content of commonly grown indigenous vegetables like Chenopodium album (Bathua), Coccinia grandis (Telakucha), Amaranthus viridis (Shaknotey), Moringa oleifera (Shojne), Alternanthera philoxeroides (Malancha), and Xanthium strumarium (Ghagra) to BARI Lalshak-1 (Amaranthus tricolor).

Suitability of early rice for the preparation of rice noodles by its starch properties analysis.

The research was conducted to explore the affiliation between the physicochemical properties of rice noodles and rice starch of early rice samples of varying amylose content. 3 various types of rice samples were analyzed to uncover how amylose content influences rice noodles' quality. Findings revealed that primarily sensory scores differ in palatability, while textural disparity lies in hardness and chewiness.

Maximizing the impact of megaprojects: Urgent implications of financial inclusion drive for effective anti-poverty measures.

Megaprojects are becoming more and more essential for poverty reduction and inclusive development. Regrettably, the CPEC mega project has yet to yield successful outcomes in Pakistan. The incorporation of financial inclusion (FI) has the potential to catalyze its outcomes.

Investigating the effect of , on using integrated computational approaches.

Unlabelled: , a notorious member of the ESKAPE pathogens, poses significant public health challenges due to its virulence and multidrug-resistant nature, particularly in methicillin-resistant (MRSA) strains. With the increasing threat of antibiotic resistance, there is an urgent need to develop novel antibiotic agents. This study therefore aims to explore the antibacterial potential of ,-dibenzoylhydrazine (DBH) as a scaffold against drug target enzymes, using integrated computational approaches.

Investigation of CuO/ITO Photoelectrode Fabricated by PVD for Efficient Photoelectrochemical Water Splitting and Hydrogen Evolution.

Hydrogen and renewable fuels were generated using cost-effective and efficient electrocatalysts for water splitting. In this work, a CuO-based photocathode is used for the water splitting to generate hydrogen energy by PVD technique. The XRD analysis reveals the deposition of CuO thin film on ITO substrates, which is monoclinic.

Early detection of autism spectrum disorder using explainable AI and optimized teaching strategies.

Autism spectrum disorder (ASD) is defined by the deficits of social relating, language, object use and understanding, intelligence and learning, and verbal and nonverbal communication. Most of the individuals with ASD have genetic conditions; however, early identification and intervention reduce the use of health services and other diagnostic procedures. The varied nature of ASD is widely acknowledged, with each affected individual displaying distinct traits.

Garlic stalk waste and arbuscular mycorrhizae mitigate challenges in continuously monocropping eggplant obstacles by modulating physiochemical properties and fungal community structure.

Background And Aims: Continuous vegetable production under plastic tunnels faces challenges like soil degradation, increased soil-borne pathogens, and diminished eggplant yield. These factors collectively threaten the long-term sustainability of food security by diminishing the productivity and resilience of agricultural soils. This research examined the use of raw garlic stalk (RGS) waste and arbuscular mycorrhizal fungi (AMF) as a sustainable solution for these issues in eggplant monoculture.

Melatonin Ameliorates Cadmium Toxicity in Tobacco Seedlings by Depriving Its Bioaccumulation, Enhancing Photosynthetic Activity and Antioxidant Gene Expression.

Soil remediation for cadmium (Cd) toxicity is essential for successful tobacco cultivation and production. Melatonin application can relieve heavy metal stress and promote plant growth; however, it remains somewhat unclear whether melatonin supplementation can remediate the effects of Cd toxicity on the growth and development of tobacco seedlings. Herein, we evaluated the effect of soil-applied melatonin on Cd accumulation in tobacco seedlings, as well as the responses in growth, physiological and biochemical parameters, and the expression of stress-responsive genes.

BrainNet: an automated approach for brain stress prediction utilizing electrodermal activity signal with XLNet model.

Brain stress monitoring has emerged as a critical research area for understanding and managing stress and neurological health issues. This burgeoning field aims to provide accurate information and prediction about individuals' stress levels by analyzing behavioral data and physiological signals. To address this emerging problem, this research study proposes an innovative approach that uses an attention mechanism-based XLNet model (called BrainNet) for continuous stress monitoring and stress level prediction.

Isolation, identification and optimization for tyrosinase production by banana peel waste for industrial application.

The study aimed to isolate, purify and optimise tyrosinase from banana peel waste for industrial use. Tyrosinase was extracted from banana peel using phosphate buffer. Purification initiated with centrifugation followed by ammonium sulphate precipitation.

Determination of Biodegradation Potential of , , and on Polyethylene, Polyethylene Terephthalate, and Polystyrene Microplastics.

Plastics are used widely in almost every field of life, but their synthetic and persistent nature makes them harmful for the environment. The aim of this research was to evaluate the degradation abilities of , , and on microplastics (MPs). MP pieces of 4 ± 1 mm, including polyethylene, polyethylene terephthalate, and polystyrene, were incubated with fungal inoculums for 30 days.

Plant growth regulators improve the yield of white lupin (Lupinus albus) by enhancing the plant morpho-physiological functions and photosynthesis under salt stress.

Background: White lupin (Lupinus albus L.) is a multi-purpose, climate resilient, pulse crop with exceptionally high protein content that makes it a suitable alternative of soybean in livestock feed. Although white lupin grows well on marginal sandy soils, previous studies have reported its sensitivity towards salinity stress.

Scientific Insights into the Quantum Dots (QDs)-Based Electrochemical Sensors for State-of-the-Art Applications.

Size-dependent optical and electronic properties are unique characteristics of quantum dots (QDs). A significant advantage is the quantum confinement effect that allows their precise tuning to achieve required characteristics and behavior for the targeted applications. Regarding the aforementioned factors, QDs-based sensors have exhibited dramatic potential for the diverse and advanced applications.

Data-centric automated approach to predict autism spectrum disorder based on selective features and explainable artificial intelligence.

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by notable challenges in cognitive function, understanding language, recognizing objects, interacting with others, and communicating effectively. Its origins are mainly genetic, and identifying it early and intervening promptly can reduce the necessity for extensive medical treatments and lengthy diagnostic procedures for those impacted by ASD. This research is designed with two types of experimentation for ASD analysis.