5 results match your criteria: "The Wuxi Fifth Affiliated Hospital of Jiangnan University[Affiliation]"

Background: To systematically evaluate the survival rate and postoperative adverse reactions of patients with hepatocellular carcinoma treated with traditional Chinese medicine combined with TACE by meta-analysis.

Methods: Four major literature databases (Cochrane Library, Embase, PubMed, and Web of Science) were retrieved to collect published English articles since 2009. After determining the random effect model or fixed utility model based on a heterogeneity test, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.

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Article Synopsis
  • - The study examines how interleukin-21 (IL-21) levels relate to the recurrence of hepatitis B virus (HBV) after stopping entecavir treatment in patients with chronic hepatitis B (CHB) who test positive for HBeAg.
  • - Blood samples from 112 CHB patients were taken at various intervals after stopping treatment, and results showed that IL-21 levels were significantly higher in patients who maintained durable virological remission compared to those who experienced relapse.
  • - The findings suggest that IL-21 levels can serve as an independent indicator for the risk of CHB relapse after treatment discontinuation, highlighting its role in the immune response for patients post-ETV therapy.
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Article Synopsis
  • A study was conducted to investigate single-nucleotide polymorphisms (SNPs) that could indicate a person's susceptibility to herb-induced liver injury (PM-DILI) in China, where this is a significant health issue.
  • Researchers analyzed genetic data from 382 participants, including patients with PM-DILI, other types of drug-induced liver injury, and healthy controls, to identify SNPs associated with PM-DILI.
  • Results revealed three SNPs, particularly rs1055348, had significantly higher frequencies in PM-DILI patients and may serve as a specific risk factor for this condition, suggesting its potential as a biomarker for both PM-DILI and other drug-induced liver injuries.
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Objectives: To assess off-treatment virological relapse rates and to determine the role of hepatitis B surface antigen (HBsAg) quantification in predicting virological relapse after stopping entecavir (ETV) treatment in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB).

Methods: One hundred and twelve CHB patients for whom ETV was stopped in accordance with the Asian Pacific Association for the Study of the Liver guidelines stopping rules were enrolled. Patient HBsAg and HBV DNA levels were monitored every 4-12 weeks during ETV treatment and after ETV cessation.

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