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Bilateral brain abnormalities associated with dominantly inherited verbal and orofacial dyspraxia.
Hum Brain Mapp
March 2003
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, Great Ormond Street Hospital for Children, NHS Trust, The Wolson Centre, Mecklenburgh Square, London, United Kingdom.
The KE family is a large three-generational pedigree in which half of the members suffer from a verbal and orofacial dyspraxia in association with a point mutation in the FOXP2 gene. This report extends previous voxel-based morphometric analyses of magnetic resonance imaging (MRI) scans (Watkins et al. [2002] Brain 125:465-478) using a bilateral conjunction analysis.
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