3 results match your criteria: "The University of Texas at Southwestern Medical School[Affiliation]"

Imaging Phospholipase D Activity with Clickable Alcohols via Transphosphatidylation.

Methods Mol Biol

July 2024

Bascom Palmer Eye Institute, Miami Integrative Metabolomics Research Center, University of Miami Miller School of Medicine, Miami, FL, USA.

Phospholipase D (PLD) is an enzyme with many functions, one of which is the synthesis of phosphatidic acid (PA), a molecule with a myriad of effects on various organ systems and processes. These numerous roles make it hard to understand the true action of PA in cellular and bodily processes. Imaging PLD activity is one way to better understand the synthesis of PA and start to elucidate its function.

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Article Synopsis
  • - Nighttime blood pressure (BP) is more closely linked to heart disease risk than daytime BP, yet its relationship with early heart disease indicators is not well understood.
  • - A study involving 897 participants found that higher nighttime BP was significantly associated with increased levels of heart-related biomarkers, specifically NT-proBNP and hs-cTnT, indicating potential heart issues.
  • - While both nighttime and daytime BP were linked to higher hs-cTnT levels, only nighttime BP showed a strong connection to NT-proBNP levels, suggesting it may be a more important factor in assessing cardiovascular health.
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