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Am J Cancer Res
December 2017
Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer CenterTX 77030, Houston, USA.
Arginine methylation of the epidermal growth factor receptor (meEGFR) increases the binding affinity of EGFR ligands and is reported to have a role in predicting response to anti-EGFR agents. This study investigated the predictive impact of meEGFR in metastatic colorectal cancer (mCRC) patients treated with anti-EGFR agents. Two patient cohorts were evaluated.
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