5 results match your criteria: "The University of Texas MD Anderson Cancer Center Division of Radiation Oncology[Affiliation]"
BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1.
J Immunother Cancer
March 2024
STCube Pharmaceuticals, Inc, Gaithersburg, Maryland, USA
Background: While Programmed cell death protein 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) blockade is a potent antitumor treatment strategy, it is effective in only limited subsets of patients with cancer, emphasizing the need for the identification of additional immune checkpoints. Butyrophilin 1A1 (BTN1A1) has been reported to exhibit potential immunoregulatory activity, but its ability to function as an immune checkpoint remains to be systematically assessed, and the mechanisms underlying such activity have yet to be characterized.
Methods: BTN1A1 expression was evaluated in primary tumor tissue samples, and its ability to suppress T-cell activation and T cell-dependent tumor clearance was examined.
Chemoradiation versus radiation alone in stage IIIB cervical cancer patients with or without human immunodeficiency virus.
Int J Gynecol Cancer
September 2021
Botswana-University of Pennsylvania Partnership, Philadelphia, Pennsylvania, USA.
Article Synopsis
- Cervical cancer is a big problem for women in sub-Saharan Africa and can be deadly, especially for those with HIV.
- Researchers studied 187 patients to see if combining chemotherapy with radiation helps them live longer compared to just using radiation.
- The results showed that women who received chemoradiation had a better chance of surviving for two years, regardless of their HIV status, especially if they didn’t get a lot of radiation.
While pre-existing cardiovascular disease (CVD) appears to be associated with poor outcomes in patients with Coronavirus Disease 2019 (COVID-19), data on patients with CVD and concomitant cancer is limited. Evaluate the effect of underlying CVD and CVD risk factors with cancer history on in-hospital mortality in those with COVID-19. Data from symptomatic adults hospitalized with COVID-19 at 86 hospitals in the US enrolled in the American Heart Association’s COVID-19 CVD Registry was analyzed.
View Article and Find Full Text PDFDefinitive radiation therapy for hepatocellular carcinoma with portal vein tumor thrombus.
Clin Transl Radiat Oncol
June 2017
The University of Texas MD Anderson Cancer Center Division of Radiation Oncology, Houston, TX, United States.
Background: The purpose of this study is to review the results of radiation therapy (RT) for hepatocellular carcinoma (HCC) with portal venous tumor thrombus (PVTT) in a Western patient population.
Methods: Thirty-four patients with HCC PVTT treated from 2007 to 2014 with RT were identified. Biologically effective dose (BED) was calculated for each patient, and greater than the median dose delivered (75 Gray (Gy)) was evaluated as a potential prognostic factor.
Relationship between fatigue, sleep quality and inflammatory cytokines during external beam radiation therapy for prostate cancer: A prospective study.
Radiother Oncol
January 2016
The University of Texas MD Anderson Cancer Center Division of Radiation Oncology, Houston, United States; Massachussettes General Hospital Institute of Health Professions, Boston, United States. Electronic address:
Background And Purpose: Mechanisms of fatigue reported during radiotherapy are poorly defined but may include inflammatory cytokines and/or sleep disturbances. This prospective, longitudinal, phase II study assessed fatigue, sleep, and serum cytokine levels during radiotherapy for early-stage prostate cancer (PCa).
Material And Methods: Twenty-eight men undergoing radiotherapy for early-stage PCa wore an Actiwatch Score to record fatigue level, sleep time, onset latency, efficiency and wake after sleep onset.