1 results match your criteria: "The University of Sydney and Royal Prince Alfred Hospital Sydney[Affiliation]"
Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers.
Vasc Health Risk Manag
October 2008
Discipline of Medicine and Department of Endocrinology, The University of Sydney and Royal Prince Alfred Hospital Sydney, New South Wales, 2006, Australia.
Diabetes mellitus is characterized by a lack of insulin causing elevated blood glucose, often with associated insulin resistance. Over time, especially in genetically susceptible individuals, such chronic hyperglycemia can cause tissue injury. One pathological response to tissue injury is the development of fibrosis, which involves predominant extracellular matrix (ECM) accumulation.
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