368 results match your criteria: "The University of South Carolina[Affiliation]"

Encouraging the Heart: A Leadership Lesson from a Stethoscope.

J Christ Nurs

December 2024

Kimberly A. Taylor, DNP, RN, NEA-BC, CNOR, is a clinical associate professor at the University of South Carolina, College of Nursing.

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Spatial and planar profiling of Rac1/Cdc42 signaling in Alzheimer's disease brain.

J Alzheimers Dis

December 2024

Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.

Article Synopsis
  • - The study focuses on the dysregulation of small GTPases Rac1 and Cdc42 in Alzheimer's disease (AD), which are important for maintaining synaptic structures and could be potential therapeutic targets.
  • - Researchers used specific antibodies to assess the activity levels of Rac1/Cdc42 and their downstream effects in brains from a triple transgenic mouse model and human AD samples.
  • - Results showed that Rac1/Cdc42 activity changes vary across different regions of the brain, with decreased activity in certain areas of AD-affected mice and variations also noted in human AD samples, indicating a complex relationship with the disease's progression.
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A qualitative study about the public's perception of primary care providers.

JAAPA

December 2024

Chris Gillette is a professor in the PA program and the Department of Epidemiology and Prevention at Wake Forest University School of Medicine in Winston-Salem, N.C. Jan Ostermann is an associate professor in the Department of Health Services Policy and Management at the University of South Carolina's Arnold School of Public Health in Columbia, S.C. Sarah Garvick is an associate professor in the PA program at Wake Forest University School of Medicine. Christine M. Everett is chief, director, and professor in the PA program at the Medical College of Wisconsin in Milwaukee, Wisc. Jessica Valente is an assistant professor in the Department of Internal Medicine at Wake Forest University School of Medicine. Aylin Aguilar Aguilar is a qualitative research specialist and lead clinical research coordinator and Kandice Lacci-Reilly is a research associate at Atrium Health Wake Forest Baptist. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Objective: With the growth of physician associates/assistants (PAs) and NPs providing primary care services, we sought to understand the public's perception of the different types of healthcare providers (HCPs) they might encounter in a clinical setting, such as primary care.

Objectives: This study aimed to evaluate public perceptions about various types of primary care providers (PCPs), identify public preferences for PCPs in relation to experience and training, and examine public preferences for PCP credentials.

Methods: We conducted semistructured interviews with adults, and used inductive and deductive coding and reflexive thematic analysis to analyze the data.

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With the number of medical school applicants more than doubling during the past 30 years, there has been an increased need to mentor premedical undergraduate students. The Vertically Integrated Training Program at the University of South Carolina School of Medicine, Columbia, was created to provide direct mentoring for college students interested in a career as a physician. Online surveys were distributed at the beginning and end of the Fall 2023 semester to gain insight into the success of the program's events from the undergraduate perspective.

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Management and Return to Play of the Elite Athlete for Common Sports-Related Injuries About the Foot.

J Am Acad Orthop Surg

October 2024

From the University of South Carolina School of Medicine- Prisma Health, Columbia, SC (Jackson and Gonzalez); Vanderbilt University School of Medicine, Nashville, TN (Strasser)- University of Virginia School of Medicine (Park) - FASSTER Consortium (Jackson III, Dr. Strasser, Gonzalez, Dr. Park).

Article Synopsis
  • Foot injuries are prevalent in collegiate and professional sports, presenting a variety of challenges in diagnosis and treatment due to their complex nature and differences across sports.
  • Advances in diagnostic tools, surgical techniques, and rehabilitation methods have significantly improved the accuracy of diagnoses and treatment outcomes for these injuries.
  • The text aims to offer updated, evidence-based treatment options for common sports-related foot injuries, including preferred methods of treatment and guidelines for when elite athletes can safely return to play.
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Article Synopsis
  • The study investigates low energy availability (LEA) in female collegiate beach volleyball athletes, emphasizing that LEA is a significant risk and often overlooked in long-term assessments.
  • Researchers measured energy availability (EA) at four timepoints: preseason and three times during a 10-week competitive season.
  • Results showed a notable prevalence of LEA among athletes, peaking at 62.5% by week 9, alongside consistently low carbohydrate intake, highlighting the need for individualized nutrition strategies.
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Article Synopsis
  • Distinguishing between benign and potentially malignant skin tumors is crucial in family medicine, and many benign tumors can be diagnosed based on their history, appearance, and growth patterns.
  • Procedures like biopsy or excision may be necessary if there's uncertainty about a diagnosis or if the lesion changes rapidly.
  • Treatment options vary based on the type of lesion and patient preference, with methods like excision, laser therapy, and cryotherapy commonly used; special considerations are needed for patients with darker skin to minimize risks like hypopigmentation.
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Objectives: In response to worldwide shortages of N95 masks during the severe acute respiratory syndrome-coronavirus-2 pandemic, various strategies have been used. The Centers for Disease Control and Prevention recommend several strategies, including simple isolation to reprocessing methods using vaporized hydrogen peroxide to guide reuse of masks up to five times. National Institute for Occupational Safety and Health (NIOSH) quantitative fit testing was performed after five trials of donning and doffing in one cohort of new masks and two cohorts of repeatedly sterilized "duckbill"-type N95 masks.

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Systemic study of pathogenic pathways and interrelationships underlying genes associated with Alzheimer's disease (AD) facilitates the identification of new targets for effective treatments. Recently available large-scale multiomics datasets provide opportunities to use computational approaches for such studies. Here, we devised a novel sease ene entification (digID) computational framework that consists of a semi-supervised deep learning classifier to predict AD-associated genes and a protein-protein interaction (PPI) network-based analysis to prioritize the importance of these predicted genes in AD.

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Aquatic Antagonists: Seaweed Dermatitis (Lyngbya majuscula).

Cutis

May 2024

Dr. Hill is from the University of South Carolina School of Medicine, Greenville. Dr. Fulton is from Spartanburg Regional Medical Center, South Carolina. Dr. McGovern is from Fort Wayne Dermatology Consultants, Indiana.

The cyanobacterium Lyngbya majuscula grows in marine and estuarine environments across the world and produces many biologically active compounds. Direct contact with L majuscula and its dermatoxins can cause seaweed dermatitis, which manifests as a papulovesicular eruption. As oceans warm, L majuscula will bloom more frequently; therefore, public awareness of L majuscula and seaweed dermatitis in oceanside communities can help promote precautions that can reduce the risk for exposure.

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Supporting Sexual and Reproductive Health for Immigrant Families Across the Lifespan.

Acad Pediatr

July 2024

Department of Pediatrics/Children's Health Services Research (TA Wilkinson), Indiana University School of Medicine, Indianapolis, Ind. Electronic address:

The ability to exercise autonomy in achieving reproductive health goals necessitates access to contraceptive and reproductive health information and medical care. Finding trusted, comprehensive, consistent and affordable reproductive care is particularly challenging for immigrants living in the United States, especially for those without legal immigration status and for those who prefer a language other than English. In immigrant communities, sexual and reproductive health (SRH) knowledge, contraceptive choice, and family planning are influenced by many factors including tension between traditional and adopted cultural norms, limited English proficiency, restricted health care access, and structural racism.

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The Association Between Surgeon Volume and Dislocation After Total Hip Arthroplasty: A Nationwide Evaluation of 5,106 Orthopaedic Surgeons.

J Am Acad Orthop Surg

January 2025

From the Department of Orthopaedic Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA (Liu, Richardson, Mayfield, Christ, Lieberman, and Heckmann), the University of South Carolina School of Medicine, Columbia, SC (Gettleman), and the Department of Orthopaedic Surgery, Louisiana State University, New Orleans, LA (Cohen-Rosenblum).

Introduction: The relationship between surgeon volume and risk of dislocation after total hip arthroplasty (THA) is debated. This study sought to characterize this association and assess patient outcomes using a nationwide patient and surgeon registry.

Methods: The Premier Healthcare Database was queried for adult primary elective THA patients from January 1, 2016, to December 31, 2019.

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Knowledge of sediment erosion and deposition can be useful for a variety of engineering, marine science, and environmental applications, but collecting detailed time-series measurements of the sediment-water interface can be challenging, particularly in coastal marine environments. We developed economical and open-source sediment level loggers to record sediment-water interface time-series data with accuracy up to 1 cm. The logger is composed of a programmable Circuit-Python (or Arduino) microcontroller and "breakout boards" that attach to a specially designed printed circuit board (PCB) and an array of evenly spaced photoresistors enclosed in a robust waterproof housing.

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Article Synopsis
  • Interspecific hybridization can result in hybrids that outperform their parent species, particularly in response to climate change and new environmental challenges.* -
  • In a study of the blue mussel complex (genus Mytilus), researchers found that hybrid mussels exhibited unique gene expression responses to temperature changes, with a notable proportion showing transgressive expression plasticity.* -
  • The research indicates that these transgressive hybrids might be crucial for survival as temperatures rise due to climate change, highlighting the need to understand their role in natural ecosystems.*
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Purpose/background: Healthcare providers experience higher rates of workplace burnout, a reality highlighted by the COVID-19 pandemic. In response, small groups, inspired by South African philosophy, , were introduced to decrease burnout and social isolation and build community and belonging. This study examines how participation in these groups can impact these measures.

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Current State of Entry-level Physical Therapy Oncology Curricula in the United States: A Faculty Survey.

J Phys Ther Educ

September 2023

Shana E. Harrington is the Clinical Professor, DPT Program Director in the Department of Exercise Science, Physical Therapy Program at the University of South Carolina, Columbia, SC. Blatt PE Center, 101H, Columbia, SC 29208 Please address all correspondence to Shana E. Harrington.

Introduction: The purpose of this study was to determine the extent of oncology rehabilitation education in current physical therapist educational programs in the United States, including oncology rehabilitation content characteristics, delivery, and instructional resources.

Review Of Literature: By 2030, more than 21 million survivors of cancer in the United States (US) will be living with multisystem side effects depending on the treatment delivered. In addition, the sociopsychological factors associated with cancer treatment require that physical therapists are equipped with a unique body of knowledge, skills, and abilities.

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Dopamine is a versatile neurotransmitter with implications in many domains, including anxiety and effortful control. Where high levels of effortful control are often regarded as adaptive, other work suggests that high levels of effortful control may be a risk factor for anxiety. Dopamine signaling may be key in understanding these relations.

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Disaster management can be difficult to teach in the classroom, yet nurses must be prepared to respond to emergency situations and feel confident doing so. Educators developed a simulated learning activity-a mock disaster drill using live volunteers as patients and emergency medical technicians-to improve disaster management preparedness, confidence, and interdisciplinary teamwork among nursing students. This article details their strategy and experience with this project.

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Cold Ambient Temperature Does Not Alter Subcutaneous Abdominal Adipose Tissue Lipolysis and Blood Flow in Endurance-Trained Cyclists.

Int J Sport Nutr Exerc Metab

May 2024

Department of Nutrition and Integrative Physiology, Institute of Sports Sciences and Medicine, Florida State University, Tallahassee, FL, USA.

This study sought to investigate the effect of cold ambient temperature on subcutaneous abdominal adipose tissue (SCAAT) lipolysis and blood flow during steady-state endurance exercise in endurance-trained cyclists. Ten males (age: 23 ± 3 years; peak oxygen consumption: 60.60 ± 4.

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Pelvic Ring Fracture Management and Subsequent Pregnancy: A Summary of Current Literature.

J Am Acad Orthop Surg Glob Res Rev

February 2024

From the Medical College of Georgia at Augusta University, Augusta, GA (Ms. Lewis); the University of South Carolina School of Medicine, Columbia, SC (Ms. Barker); the Western Orthopaedics, Denver, CO (Dr. Griswold); the Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA (Dr. Blair); and the Department of Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, PA (Dr. Davis).

Introduction: The incidence of pelvic ring injuries is 34.3% per 100,000 capita. No studies have determined the ability of a female patient to have a vaginal delivery after undergoing pelvic fracture fixation.

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Objective: To compare fertility in India to both low-to-middle-income and high-income countries (LMICs and HICs) and describe the patterns that have accompanied India's transition to low fertility.

Methods: We use data from the Demographic and Health Surveys (DHS), the United Nations (UN), and the Organisation for Economic Co-operation and Development (OECD) to observe factors associated with fertility decline in 36 Indian states and 76 countries.

Results: Although fertility in India has declined to levels similar to HICs, women's entry into marriage and initiation of childbearing are more in line with patterns found in LMICs.

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The increased politicization of sexual and reproductive health has created barriers to medically necessary care. In absence of formal health care, social ties become critical sources of information and resources, yet the disclosure of stigmatized health needs carries significant risk. How do people navigate the risks and benefits of disclosure when seeking care for stigmatized needs? Drawing on original survey data (N = 153) and in-depth interviews (N = 55) with women who attempted a self-managed abortion, I first describe the distinct roles of weak and strong ties in women's health-seeking experiences.

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Two Randomized Trials of Low-Dose Calcium Supplementation in Pregnancy.

N Engl J Med

January 2024

From St. John's Research Institute (P.D., R.F.), St. John's Medical College (T.T., J.M.R., A.V.K.), and Bruhat Bengaluru Mahanagara Palike (N.B., R.S.) - all in Bangalore, India; the Africa Academy for Public Health (A.M., S.M.K., M.M.S.), Muhimbili University of Health and Allied Sciences (M.B., A.B.P.), Dar es Salaam Regional Medical Office of Health (N.O.S.), and Ifakara Health Institute (H.M.M.) - all in Dar es Salaam, Tanzania; the Harvard T.H. Chan School of Public Health (C.R.S., M.W., N.P., C.P.D., W.W.F.), Harvard Medical School (M.W., C.P.D.), and Boston Children's Hospital (C.P.D.) - all in Boston; Columbia University Medical Center, New York (B.J.W.); and the University of South Carolina, Columbia (N.P.).

Background: The World Health Organization recommends 1500 to 2000 mg of calcium daily as supplementation, divided into three doses, for pregnant persons in populations with low dietary calcium intake in order to reduce the risk of preeclampsia. The complexity of the dosing scheme, however, has led to implementation barriers.

Methods: We conducted two independent randomized trials of calcium supplementation, in India and Tanzania, to assess the noninferiority of a 500-mg daily dose to a 1500-mg daily dose of calcium supplementation.

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