Species in Dromedary Camels () and Ruminants from Somalia.

Ehrlichioses, caused by species, are tick-borne diseases (TBDs) that affect animals and humans worldwide. This study aimed to investigate the molecular occurrence of spp. in 530 animals (155 Dromedary camels, 199 goats, 131 cattle, and 45 sheep) in the Benadir and Lower Shabelle regions of Somalia.

Mixed-Effects Model to Assess the Effect of Disengagements on Speed of an Automated Shuttle with Sensors for Localization, Navigation, and Obstacle Detection.

The focus of this study is to investigate the underexplored operational effects of disengagements on the speed of an automated shuttle, providing novel insights into their disruptive impact on performance metrics. For this purpose, global positioning system data, disengagement records, weather reports, and roadway geometry data from an automated shuttle pilot program, from July to December 2023, at the University of North Carolina in Charlotte, were collected. The automated shuttle uses sensors for localization, navigation, and obstacle detection.

Trauma Survivors Network: history and evolution of a program empowering survivors and families impacted by traumatic injury.

The Trauma Survivors Network (TSN), a program of the American Trauma Society (ATS), has a unique history spanning decades with a vision to continue expanding and strengthening services to support survivors and families impacted by traumatic injury. Since the COVID-19 pandemic, the ATS has adapted TSN services to provide both virtual and in-person services for trauma survivors, increasing equity and inclusion for many survivors to access TSN services for the first time. The recent policy changes in the American College of Surgeons Committee on Trauma provide an impetus for the TSN to grow and expand services in support of a diverse group of trauma survivors and their loved ones.

A Collaborative Online International Learning Experience for Doctoral Nursing Students and Faculty From Three Countries: Reshaping the Educational Landscape.

The COVID-19 pandemic presented opportunities for educational innovations and the development of intercultural learning experiences. A global health assignment guided by a collaborative online international learning pedagogy was assigned to doctoral nursing students from three different countries. Icebreaker activities, along with the Culturally You diagram, commenced the team-building process.

Efficacy of an online self-management program for chronic burn pain: A randomized controlled trial of the Take Charge of Burn Pain program.

This randomized controlled trial investigated the effectiveness of an online self-management program, "Take Charge of Burn Pain (TCBP)," for 96 individuals living with chronic burn pain. Participants were randomly assigned to either the 7-week TCBP program integrating cognitive-behavioral therapy techniques, pain education, and self-management strategies or an attention control group focused on general burn recovery information. Assessments conducted at baseline, post-treatment, and 2- and 5-month follow-ups included measures of pain severity, pain interference, pain self-efficacy, posttraumatic stress disorder symptoms, and depression.

Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.

Proteostasis, the maintenance of cellular protein balance, is essential for cell viability and is highly conserved across all organisms. Newly synthesized proteins, or "clients," undergo sequential processing by Hsp40, Hsp70, and Hsp90 chaperones to achieve proper folding and functionality. Despite extensive characterization of post-translational modifications (PTMs) on Hsp70 and Hsp90, the modifications on Hsp40 remain less understood.

Precision Adverse Drug Reactions Prediction with Heterogeneous Graph Neural Network.

Accurate prediction of Adverse Drug Reactions (ADRs) at the patient level is essential for ensuring patient safety and optimizing healthcare outcomes. Traditional machine learning-based methods primarily focus on predicting potential ADRs for drugs, but they often fall short of capturing the complexity of individual demographics and the variations in ADRs experienced by different people. In this study, a novel framework called Precise Adverse Drug Reaction (PreciseADR) for patient-level ADR prediction is proposed.

Hemoplasma in melon-headed whale (Peponocephala electra, Gray, 1846), Veracruz, Mexico.

Hemoplasmas (HM) infect a wide range of mammals and may cause hemolytic anemia. We detected HM in a melon-headed whale (Peponocephala electra) stranded in Veracruz, Mexico. Sequencing and phylogenetic analysis of 16S and 23S rDNA indicated the presence of a HM that was previously detected in cetaceans from South America.

Serological and molecular detection of Toxoplasma gondii and Neospora caninum in ruminants from Somalia.

Toxoplasma gondii and Neospora caninum infect a wide range of domestic and wild animals, including humans, in the case of T. gondii, and cause economic losses in livestock due to abortion and neonatal mortality. In Somalia, zoonotic diseases are concerning due to cultural practices and livestock's economic importance, but surveillance is limited.

Enhanced pollen tube performance at high temperature contributes to thermotolerant fruit and seed production in tomato.

Rising temperature extremes during critical reproductive periods threaten the yield of major grain and fruit crops. Flowering plant reproduction depends on the ability of pollen grains to generate a pollen tube, which elongates through the pistil to deliver sperm cells to female gametes for double fertilization. We used tomato as a model fruit crop to determine how high temperature affects the pollen tube growth phase, taking advantage of cultivars noted for fruit production in exceptionally hot growing seasons.

Ticks and hemoplasma screening in dromedary camels (Camelus dromedarius) from Somalia.

Hemotropic mycoplasmas (hemoplasmas) are small pleomorphic bacteria that parasitize the surface of red blood cells of mammals. Hemoplasmas have been described in different species from the Camelidae Family, such as llamas and alpacas (South American camelids), but data on dromedary camels (Camelus dromedarius) are limited to a few reports. Somalia has one of the world's largest dromedary camel populations, and studies on hemoplasmas and tick-borne pathogens are lacking.

Single-shot quantitative phase microscopy: a multi-functional tool for cell analysis.

This study showcases the multifunctionality of a single-shot quantitative phase microscopy (QPM) system for comprehensive cell analysis. The system captures four high-contrast images in one shot, enabling tasks like cell segmentation, measuring cell confluence, and estimating cell mass. We demonstrate the usability of the QPM system in routine biological workflows, showing how its integration with computational algorithms enables automated, precise analysis, achieving accuracy scores between 85% and 97% across samples with varying cell densities, even those with low signal-to-noise ratios.

Optimized Fabrication of Dendritic Mesoporous Silica Nanoparticles as Efficient Delivery System for Cancer Immunotherapy.

In the past decade, cancer immunotherapy has revolutionized the field of oncology. Major immunotherapy approaches such as immune checkpoint inhibitors, cancer vaccines, adoptive cell therapy, cytokines, and immunomodulators have shown great promise in preclinical and clinical settings. Among them, immunomodulatory agents including cancer vaccines are particularly appealing; however, they face limitations, notably the absence of efficient and precise targeted delivery of immune-modulatory agents to specific immune cells and the potential for off-target toxicity.

First report of the soft tick Ornithodoros mimon (Ixodida: Argasidae) in Alagoas State, Northeastern Brazil.

The Brazilian tick fauna currently comprises 77 valid species categorized into two families: Ixodidae (53 species) and Argasidae (24 species). In the state of Alagoas, only six Ixodid ticks have been reported to date, with no previous reports of ticks in the Argasidae family. Here, we assessed 33 White-eared Opossum (Didelphis albiventris Lund, 1840) rescued in the metropolitan region of Maceió and referred to the Wild Animal Screening Center (Cetas) in the city.

Quality Measurement of Consumer Health Questions: Content and Language Perspectives.

Background: Health information consumers increasingly rely on question-and-answer (Q&A) communities to address their health concerns. However, the quality of questions posted significantly impacts the likelihood and relevance of received answers.

Objective: This study aims to improve our understanding of the quality of health questions within web-based Q&A communities.

Solvent-mediated oxide hydrogenation in layered cathodes.

Self-discharge and chemically induced mechanical effects degrade calendar and cycle life in intercalation-based electrochromic and electrochemical energy storage devices. In rechargeable lithium-ion batteries, self-discharge in cathodes causes voltage and capacity loss over time. The prevailing self-discharge model centers on the diffusion of lithium ions from the electrolyte into the cathode.

The eukaryome of modern microbialites reveals distinct colonization across aquatic ecosystems.

Protists are less studied for their role and diversity in ecosystems. Notably, protists have played and still play an important role in microbialites. Microbialites, or lithified microbial mats, represent the oldest evidence of fossil biofilms (~3.

Transcriptomic analysis of the spatiotemporal axis of oogenesis and fertilization in .

hermaphrodite presents a unique model to study the formation of oocytes. However, the size of the model animal and difficulties in retrieval of specific stages of the germline have obviated closer systematic studies of this process throughout the years. Here, we present a transcriptomic level analysis into the oogenesis of hermaphrodites.

Mammography and Breast Ultrasonography Services in Ghana, Availability, and Geographic Access.

Purpose: Breast cancer is the leading type of cancer diagnosed and the second leading cause of cancer-related death in Ghana. Mammography and ultrasound have proven benefits in the early detection of breast cancer. This study evaluates mammography, breast ultrasound, and radiology work force availability throughout Ghana.

Hemoplasmas in wild rodents and marsupials from the Caatinga Biome, Brazil.

A total of 231 blood samples from wild mammals belonging to the orders Rodentia (n = 142) and Didelphimorphia (n = 89) were screened by real-time PCR assay (qPCR), being six Rhipidomys sp., 118 Thrichomys laurentius, nine Rattus rattus, four Kerodon rupestris, five Necromys lasiurus, 42 Didelphis albiventris and 47 Monodelphis domestica. Results using qPCR showed that 32 of the total 231 (13.

Fatal crashes involving vehicles with driver warning systems: Identifying risk factors using a correlated random parameters ordered logit modeling approach.

Recent advancements in vehicular technology are expected to enhance traffic safety by either warning the drivers or by automating the tasks related to driving to reduce the human driver's involvement. The driver warning systems (DWSs) are designed to warn drivers in unsafe situations such as forward collision, lane departure, or when changing lanes with vehicles in blind spot areas. Although these features are designed to enhance safety, recent crash data shows vehicles with these features are still getting involved in crashes, making it necessary to identify the contributing factors.

Lightweight Electrolyte Design for Li/Sulfurized Polyacrylonitrile (SPAN) Batteries.

Sulfurized polyacrylonitrile (SPAN) recently emerges as a promising cathode for high-energy lithium (Li) metal batteries owing to its high capacity, extended cycle life, and liberty from costly transition metals. As the high capacities of both Li metal and SPAN lead to relatively small electrode weights, the weight and specific energy density of Li/SPAN batteries are particularly sensitive to electrolyte weight, highlighting the importance of minimizing electrolyte density. Besides, the large volume changes of Li metal anode and SPAN cathode require inorganic-rich interphases that can guarantee intactness and protectivity throughout long cycles.