A PHP Error was encountered

Severity: 8192

Message: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated

Filename: helpers/my_audit_helper.php

Line Number: 8900

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 8900
Function: str_replace

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3362
Function: formatAIDetailSummary

File: /var/www/html/application/controllers/Search.php
Line: 168
Function: pubMedSearch_Global

File: /var/www/html/index.php
Line: 316
Function: require_once

The University of North Carolina At Cha... Publications | LitMetric

6,832 results match your criteria: "The University of North Carolina At Chapel Hill[Affiliation]"

'Biological aging clocks' - composite molecular markers thought to capture an individual's biological age - have been traditionally developed through bulk-level analyses of mixed cells and tissues. However, recent evidence highlights the importance of gaining single-cell-level insights into the aging process. Microglia are key immune cells in the brain shown to adapt functionally in aging and disease.

View Article and Find Full Text PDF

Background: High-grade gliomas (HGGs) are the most aggressive type of gliomas and have the poorest outcomes. Chromatin remodeling (CR) genes have been implicated in multiple oncogenic pathways in numerous cancer types. In gliomagenesis, CR genes have been implicated in regulating the stemness of glioma cells, the tumor microenvironment (TME), and resistance to therapies.

View Article and Find Full Text PDF

Introduction: Abdominal binders consist of a wide compression belt that encircles the abdomen, theoretically supporting the abdominal wall. However, their use after ventral hernia repair is debated. Therefore, this meta-analysis evaluates their efficacy.

View Article and Find Full Text PDF

Low racial/ethnic diversity among public health academics undermines our research, teaching, and practice. One important step for addressing this problem is to increase the diversity of applicant pools for open faculty positions. In this commentary, we share our experience conducting a tenure-track faculty search at a large public university.

View Article and Find Full Text PDF

Glioblastoma (GBM) is the most common primary malignant brain tumor diagnosed in adults, carrying with it an extremely poor prognosis and limited options for effective treatment. Various cell therapies have emerged as promising candidates for GBM treatment but fail in the clinic due to poor tumor trafficking, poor transplantation efficiency, and high systemic toxicity. In this study, we design, characterize, and test a 3D-printed cell delivery platform that can enhance the survival of therapeutic cells implanted in the GBM resection cavity.

View Article and Find Full Text PDF
Article Synopsis
  • Empirical research indicates strong links between teasing about weight and muscularity and eating behaviors in men, but most studies have overlooked the impact of different types of teasing.
  • This study analyzed 596 Chinese adult men to explore how four teasing categories—high weight, low weight, high muscularity, and low muscularity—affect eating disorder symptoms and intuitive eating through various statistical approaches.
  • Results revealed that the "Low Teasing" group experienced the least eating disorder issues and the most intuitive eating, while the "High Weight-High Muscularity" group had the most severe eating disorder symptoms, emphasizing the need for targeted interventions for men facing different teasing experiences.
View Article and Find Full Text PDF

Fires at the wildland-urban interface (WUI) are increasing in magnitude and frequency, emitting organic aerosol (OA) with unknown composition and atmospheric impacts. In this study, we investigated the chemical composition of OA produced through the 600 °C pyrolysis of ten urban materials in nitrogen, which were subsequently aged under UV light for 2 h. The analysis utilized ultrahigh-performance liquid chromatography (UHPLC) separation, coupled with a photodiode array (PDA) detector and a high-resolution mass spectrometer (HRMS) for molecular characterization.

View Article and Find Full Text PDF

Fast and accurate assessment of skin mechanics holds great promise in diagnosing various epidermal diseases, yet substantial challenges remain in developing simple and wearable strategies for continuous monitoring. Here, we present a design concept, named active near-infrared spectroscopy patch (ANIRP) for continuously mapping skin mechanics. ANIRP addresses these challenges by integrating near-infrared (NIR) sensing with mechanical actuators, enabling rapid measurement (<1 s) of Young's modulus, high spatial sensing density (~1 cm), and high spatial sensitivity (<1 mm).

View Article and Find Full Text PDF

The Duke University Clinical and Translational Science Institute Community Engaged Research Initiative (CERI) created an e-Library in 2018. This e-Library was developed in response to requests from academic researchers and the community for reliable, easily accessible information about community-engaged research approaches and concepts. It was vetted by internal and external partners.

View Article and Find Full Text PDF

Alcoholic ketoacidosis: confused diagnosis.

BMJ Case Rep

November 2024

Family Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

A woman in her 30s presented with a 3-day history of nausea, vomiting and abdominal pain. She was found to be in ketoacidosis with an elevated serum glucose level of 18.2 mmol/L (328 mg/dL).

View Article and Find Full Text PDF

Objective: This study examined cross-sectional and longitudinal associations of intermittent fasting (IF) engagement with body mass index (BMI), both thinness-oriented and muscularity-oriented eating disorder (ED) psychopathology, eating-related psychosocial impairment, and intuitive eating.

Method: Using a longitudinal design, 491 Chinese adults (M = 30.33 years, SD = 7.

View Article and Find Full Text PDF

Background: Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is a minimally invasive technique for treating gastric outlet obstruction (GOO). The aim of this study was to assess the outcomes of EUS-GE in managing benign GOO caused by duodenal stenosis in patients with acute pancreatitis.

Methods: This international retrospective study analyzed patients treated with EUS-GE for GOO caused by acute pancreatitis until December 2023, evaluating technical and clinical success, adverse events, and reintervention.

View Article and Find Full Text PDF

Background: The number of older adults with type 1 diabetes (T1D) is increasing. Use of automated insulin delivery (AID) may influence nutrition and eating behaviors. We explored how three eating styles (restrained, external, emotional) differ between older adults with T1D who use and do not use AID.

View Article and Find Full Text PDF

Early degenerative changes are different between partial and complete anterior cruciate ligament injury and associate with joint instability in a skeletally immature porcine model.

Osteoarthritis Cartilage

November 2024

Joint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina at Chapel Hill, Raleigh, NC 27695, USA; Comparative Medicine Institute, North Carolina State University, Raleigh, NC 27607, USA; Department of Orthopaedics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

Objective: Anterior cruciate ligament (ACL) injuries are a major problem in the pediatric and adolescent populations. Some of these injuries are only partial; yet, there is limited data to inform clinical treatment of such partial tears. It is unknown how injury partial injury impacts long-term degenerative changes in the joint relative to complete injury.

View Article and Find Full Text PDF

Systematic Review of Obstetric and Child Outcomes of Prenatal Exposure to Inhalants in the Context of a Use Disorder.

J Addict Med

November 2024

From the University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC (ESK); Addiction Medical Services of Wisconsin, Onalaska, WI (CWS); Health Sciences Library, University of North Carolina at Chapel Hill, Chapel Hill, NC (JLC); and Horizons Division and Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, and Departments of Psychiatry and Behavioral Sciences and Obstetrics and Gynecology, School of Medicine, Johns Hopkins University, Baltimore, MD (HEJ).

Objectives: Inhalants are often used for their psychoactive effects, producing feelings of euphoria. Inhalant and solvent use is a serious public health concern, yet little is known about their effects on perinatal, fetal, and child outcomes. The aim of our review is to evaluate the impact of inhalant use by pregnant people on maternal, fetal, neonatal, and early childhood outcomes.

View Article and Find Full Text PDF

Risk of Recurrent Prolapse by Extent of Mesh Excision Procedures: A Multicenter Study.

Urogynecology (Phila)

November 2024

From the Division of Urogynecology, Department of Obstetrics & Gynecology, Alpert Medical School of Brown University, Providence, RI.

Importance: There is limited evidence guiding surgeons in how much mesh to resect when treating mesh complications.

Objective: The aim of the study was to compare rates of recurrent prolapse after mesh excisional surgical procedures for prolapse mesh complications.

Study Design: This multicenter, retrospective cohort study included patients, identified by Current Procedural Terminology codes, who were treated surgically for prolapse mesh complications at 8 institutions between 2010 and 2019.

View Article and Find Full Text PDF

Theoretical models and empirical research have highlighted the impact of economic disadvantage on children's psychosocial development broadly and the onset, maintenance, and treatment of early-onset (3-8 years) behavior disorders (BDs) more specifically. In the context of intervention, evidence suggests that economic disadvantage may pose risk for diminished parent-mediated treatment efficacy (e.g.

View Article and Find Full Text PDF

Subclinical malaria among pregnant women living in refugee settlements in Northern Uganda.

Ther Adv Infect Dis

November 2024

Department of Environmental Sciences and Engineering, the University of North Carolina at Chapel Hill, 0300 Michael Hooker Research Center, 135 Dauer Drive, Campus Box # 7431, Chapel Hill, NC 27599, USA.

Background: Malaria during pregnancy contributes to significant perinatal morbidity and mortality, accounting for almost 25% of global maternal mortality. However, the epidemiology and risk factors for subclinical malaria among pregnant women living in refugee settlements is poorly understood.

Objective: To determine the prevalence and predictors of subclinical malaria among pregnant women in refugee settlements in Northern Uganda.

View Article and Find Full Text PDF

Prior research demonstrates positive associations between muscularity dissatisfaction and an array of negative health outcomes, including muscularity-oriented disordered eating, eating-related psychosocial impairment, and psychological distress. However, muscularity dissatisfaction differs by gender and is not always linked to these outcomes, indicating the existence of moderators of these associations. We proposed and examined muscularity bias internalization (MBI) as a moderator of these associations.

View Article and Find Full Text PDF

Climate change has been repeatedly linked to phenological shifts in many taxa, but the factors that drive variation in phenological sensitivity remain unclear. For example, relatively little is known about phenological responses in areas that have not exhibited a consistent warming trend, making it difficult to project phenological responses in response to future climate scenarios for these regions. We used an extensive community science dataset to examine changes in the adult flight onset dates of 38 butterfly species with interannual variation in spring temperatures in the Piedmont region of North Carolina, a region that did not experience a significant overall warming trend in the second half of the 20th century.

View Article and Find Full Text PDF
Article Synopsis
  • The perinatal period involves significant changes for women, including psychological and social stressors, which heighten vulnerabilities and impact mental health during and after pregnancy.
  • A systematic review was conducted on English-language publications, focusing on randomized controlled trials that assessed postpartum mental health using the Edinburgh Postnatal Depression Scale.
  • The review found that higher physical activity levels during pregnancy are linked to better mental health outcomes postpartum, with low-intensity exercises like yoga being particularly effective in reducing depressive symptoms.
View Article and Find Full Text PDF

Usability of Light-Linking Technology for Infusion Line Identification: A Simulation Study With ICU Nurses.

J Infus Nurs

November 2024

Author Affiliations: Department of Implementation Science (Huffman and Munn), Center for Experiential and Applied Learning (Saunders), and Department of Biostatistics and Data Science (Russell), Wake Forest University School of Medicine (Gonzales), Winston-Salem, North Carolina; Center for Nursing Research (Huffman) and Comprehensive Cancer Center (Butcher), Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina (Hampton).

Critical care nurses are faced with increasing task loads due to increasing patient complexity. In addition to this complexity, most critical care patients have a maze of infusion and monitoring lines that must be navigated when administering medications. Task load is escalated when a nurse must identify an injection port and administer a medication rapidly.

View Article and Find Full Text PDF

Simulations are an essential tool in all areas of population genetic research, used in tasks such as the validation of theoretical analysis and the study of complex evolutionary models. Forward-in-time simulations are especially flexible, allowing for various types of natural selection, complex genetic architectures, and non-Wright-Fisher dynamics. However, their intense computational requirements can be prohibitive to simulating large populations and genomes.

View Article and Find Full Text PDF

The Community Multiscale Air Quality Model (CMAQ) is a local- to hemispheric-scale numerical air quality modeling system developed by the U.S. Environmental Protection Agency (USEPA) and supported by the Community Modeling and Analysis System (CMAS) center.

View Article and Find Full Text PDF