Mental health care for parents of babies with congenital heart disease during intensive care unit admission: Systematic review and statement of best practice.

Introduction: Congenital heart disease (CHD) is one of the most common causes of infant admission to pediatric intensive care and is associated with profound psychological stress for mothers, fathers and their infants. Intensive care unit admission represents an opportunity to offer evidence-based strategies to prevent or minimize severe psychological distress and promote secure bonding and attachment, alongside high-quality infant medical care.

Objectives: We aimed to identify, synthesize and critically appraise published evidence on the efficacy and cost-effectiveness of mental health interventions delivered in neonatal, pediatric or cardiac intensive care units for parents of infants with CHD.

Peptide-Mediated Liposome Fusion as a Tool for the Detection of Matrix Metalloproteinases.

Biological cells continue to inspire the development of technologies toward rapid, sensitive, and selective detection of analytes. Membrane fusion is a key biological event in living cells that involves a highly selective recognition mechanism controlled by different functional proteins. Herein, liposome-liposome fusion mediated by coiled-coil forming peptides JR2EC and JR2KC to mimic biological membrane fusion is reported.

Multicompartmentalized Microreactors Containing Nuclei and Catalase-Loaded Liposomes.

Multicompartmentalized microreactors are considered as cell mimics with hierarchical structures inspired by mammalian cells. We report the successful assembly and encapsulation of purified nuclei from RAW 264.7 cells (pNuc) into alginate-based microreactors.

Oxygen-deficient bismuth tungstate and bismuth oxide composite photoanode with improved photostability.

A homogeneous layer of BiO-BiWO composite (BWO/BiO) thin film was fabricated using a combination of electrodeposition and thermal treatment. The evenly distributed BiWO component within the BiO layer was found to be important in stabilising the photoelectrochemical performances of BiO photoanode by promoting the photoelectron transport. The unmodified BiO suffered from severe photocorrosion as proven by X-ray diffraction (XRD) and inductively coupled plasma (ICP) analyses while the composite thin film was active without noticeable activity decay for at least 3 h of illumination.

Progress and Promise of Nitric Oxide-Releasing Platforms.

Nitric oxide (NO) is a highly potent radical with a wide spectrum of physiological activities. Depending on the concentration, it can enhance endothelial cell proliferation in a growth factor-free medium, mediate angiogenesis, accelerate wound healing, but may also lead to tumor progression or induce inflammation. Due to its multifaceted role, NO must be administered at a right dose and at the specific site.

The Isolation of Pure Populations of Neurons by Laser Capture Microdissection: Methods and Application in Neuroscience.

In mammals, the central nervous system (CNS) is constituted of various cellular elements, posing a challenge to isolating specific cell types to investigate their expression profile. As a result, tissue homogenization is not amenable to analyses of motor neurons profiling as these represent less than 10% of the total spinal cord cell population. One way to tackle the problem of tissue heterogeneity and obtain meaningful genomic, proteomic, and transcriptomic profiling is to use laser capture microdissection technology (LCM).

Do electronic discharge summaries contain more complete medication information? A retrospective analysis of paper versus electronic discharge summaries.

Complete, accurate and timely hospital discharge summaries are important for continuity of care. The aim of this study was to evaluate the effectiveness of an electronic discharge summary system in improving the medication information provided compared to the information in paper discharge summaries. We conducted a retrospective audit of 199 paper and 200 electronic discharge summaries from a 350-bed teaching hospital in Sydney, Australia.