Infantile Frey's syndrome.

Frey's syndrome in children is rare and often erroneously attributed to food allergy. Here we describe a case of Frey's syndrome in an infant and provide a review of the literature. Awareness of this condition is important for the Otolaryngologist in order to avoid unnecessary medical costs and procedures and provide reassurance to both parents and primary care providers in the setting of this benign condition.

Cardiac arrest in the PACU: an analysis of evolving challenges for perianesthesia nursing.

Cardiac arrest in the PACU is a rare and poorly described event, with attendant limitations to experiential learning for the perianesthesia nurse. Good outcome from in-hospital cardiac arrest events differs partly because of variability in direct causes and clinical responses. Development of in-house training programs tailored to retain basic and advanced life support skills and enhance perianesthesia nurse responses to PACU arrests are essential to improving outcomes.

Anal intraepithelial neoplasia in women with genital intraepithelial neoplasia.

Objective: To estimate the prevalence of anal intraepithelial neoplasia in heterosexual women with genital intraepithelial neoplasia, and to compare anal cytology with colposcopy for their effectiveness in anal intraepithelial neoplasia screening.

Methods: Women with confirmed intraepithelial neoplasia on the cervix, vagina, or vulva were referred for gynecologic oncology care. All patients underwent anal cytology and high-resolution anoscopy.

Impact of patient financial incentives on participation and outcomes in a statin pill-splitting program.

Objectives: To examine willingness to participate in a pill-splitting program and the impact of pill splitting on patients' adherence and lipid control.

Study Design: Nested randomized trial.

Methods: A total of 200 patients who used statins and were candidates for a pill-splitting regimen were identified from a large university-based health plan.

Home study course: spring 2001.

Objective: The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his or her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management or that demonstrate new and important knowledge in the area of colposcopy or pathology. Participants may benefit from reading and studying the material or from testing their knowledge by answering the questions.

Vulvar lichen sclerosus : pathophysiology and treatment.

Lichen sclerosus is a chronic disorder of the skin and mucosal surfaces, and is most commonly seen on the female genital skin. It also occurs on other areas of the body. Any age group may be affected, although it is seen more often in elderly women.

Attenuation correction for single photon emission computed tomography myocardial perfusion imaging.

The specificity of cardiac single photon emission computed tomography (SPECT) perfusion imaging is significantly affected by internal photon absorption. Commonly referred to as anterior wall breast and inferior wall diaphragm attenuation artifacts, even when following characteristic patterns in women and men, the reduced activity produced can be difficult to differentiate from real perfusion defects. Unfortunately, wide variations in body habitus result in unpredictable variations in tissue attenuation and the specificity of uncorrected SPECT is unacceptably low in many laboratories.

Premenarchal vaginal discharge: findings of procedures to rule out foreign bodies.

Study Objective: Vaginal discharge in children is a common gynecologic complaint and may be resistant to symptomatic and/or antibiotic treatment. In recurrent or unresponsive patients, an evaluation to rule out a foreign body is traditionally recommended. The objective of this study is to review cases of vaginal discharge referred to our institution and assess outcome and diagnosis in those who required irrigation or vaginoscopy to rule out a foreign body.

The role of arthroscopic synovectomy in the management of hemarthrosis in hemophilia patients: financial perspectives.

Purpose: The purpose of this study was to determine the financial efficacy of arthroscopic synovectomy in hemophilia patients with recurrent hemarthroses.

Type Of Study: Cost-benefit analysis.

Methods: A retrospective chart review from 1993 through 1999 yielded 11 cases of arthroscopic synovectomies performed for recurrent hemarthroses at the University of Michigan.

Prognostic factors in malignant mixed tumors of the salivary gland: correlation of immunohistochemical markers with histologic classification.

Malignant mixed tumor of salivary glands is a rare tumor whose variable behavior and prognosis are related for the most part to the clinical stage and histologic grade of the carcinomatous component. The purpose of this study is to predict prognosis by comparing the histologic grading and subclassification of the carcinomatous component with the immunohistochemical reactivity for E-cadherin, P53 mutation protein, and cellular proliferation (Ki67). Stains were performed on formalin-fixed paraffin-embedded tissue sections from 18 cases of malignant mixed tumor.

Mitral valve surgery in the patient with left ventricular dysfunction.

Mitral regurgitation (MR) is a frequent complication of end-stage cardiomyopathy. Historically, these patients were managed either medically or with mitral valve replacement, both associated with poor outcomes. We studied 125 patients with cardiomyopathy and severe MR who were managed with mitral reconstruction.

The relationship between Parson's tubercle and the insertion of the anterior horn of the medial meniscus.

Purpose: The purpose of this investigation was to correlate the anatomic characteristics of the third intercondylar tubercle of Parsons (TITP) with the insertional variations of the anterior horn of the medial meniscus using precise measurements in an anatomic cadaver study. Our hypothesis was that the height of the TITP would correlate with the degree of inferior insertion of the medial meniscus.

Type Of Study: A cadaver study using a convenience sample.

Prolonged partial liquid ventilation in spontaneously breathing awake animals.

Objective: To date, studies of partial liquid ventilation (PLV) have examined its effects acutely in anesthetized and mechanically ventilated subjects. We set out to develop a model of prolonged PLV in awake, spontaneously breathing animals.

Design: Animal case series

Setting: Cardiopulmonary physiology laboratory.

Surgical delay for acute type A dissection with malperfusion.

Background: An acute type A aortic dissection is considered a surgical emergency. Review of the risk factors for a type A dissection showed that preoperative malperfusion was associated with a 22% (2/9) intraoperative mortality and an 89% (8/9) hospital mortality. Intraoperative deaths were secondary to pulmonary failure resulting from capillary leak; the remaining patients died of multiorgan failure resulting from reperfusion injury.

Reperfusion adequacy and functional recovery.

Ischemic myocardium undergoes many physiologic changes, including alterations in contractile function, histologic condition, and oxygen utilization. Reperfusion of ischemic myocardium may reverse some of these changes; however, the level of reperfusion needed for adequate functional recovery, as opposed to myocyte salvage, remains controversial. This study examines the effects of varying levels of reperfusion following ischemia on functional parameters of recovery.

MR imaging of the brain in five members of a family with Pelizaeus-Merzbacher disease.

MR imaging was performed in five members of a family afflicted with Pelizaeus-Merzbacher disease. The individuals imaged included a male proband, his mother, and three maternal uncles. Clinically affected members showed generalized white matter signal aberration consistent with dys- and demyelination, basal ganglia, and thalamic signal aberration suggestive of pathologic iron storage and diffuse brain atrophy.

Determinants of platelet catecholamine content: uptake and retention of catecholamines by human platelets in vitro.

The utility of platelet catecholamine determination in assessing sympathetic nervous system activity depends on the extent to which transient fluctuations of plasma catecholamine concentration can affect platelet catecholamine content. In order to quantitate the relationship between plasma and platelet catecholamine content, the concentrations of norepinephrine, epinephrine and dopamine needed to produce an increase in platelet catecholamines in vitro were determined. The threshold for epinephrine accumulation was 10(-9)M while the thresholds for norepinephrine and dopamine were an order of magnitude higher.