497 results match your criteria: "The University of Louisville[Affiliation]"

Introduction: Empathy is a fundamental element of high-quality healthcare, though it has been shown to be in decline among medical students and residents. Appeals have therefore been made for the development of evidence-based empathy-enhancing experiential learning and training models. Bringing Art to Life (BATL) is a service-learning program designed within experiential learning pedagogy for psychology and pre-healthcare students.

View Article and Find Full Text PDF

A Longitudinal Analysis of Long Working Hours and the Onset of Psychological Distress.

J Occup Environ Med

January 2025

From the University of Louisville, Louisville, Kentucky (E.E., S.K., D.L., D.A.); and Georgia State University, Atlanta, Georgia (C.J.).

Objectives: There is a paucity of longitudinal studies examining the relationship between working hours and the development of psychological distress (PD) among US workers. This study utilized a longitudinal approach to examine this relationship.

Methods: The 2010-2019 Medical Expenditure Panel Survey (MEPS) data was utilized.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how race and ethnicity influence antibiotic usage among hospitalized children, utilizing data from over 846,000 inpatient visits in 2022 across the Pediatric Health Information System.
  • Findings indicate that Non-Hispanic Black children were less likely to receive antibiotics compared to Non-Hispanic White children, while Non-Hispanic Native Hawaiian/Other Pacific Islander children had a higher likelihood of receiving them.
  • The authors suggest that hospitals should re-evaluate their policies regarding antibiotic prescriptions to address these disparities, and further research is needed to better understand the factors contributing to these variations in treatment.
View Article and Find Full Text PDF

Use of radiofrequency ablation of the vaginal canal for genitourinary syndrome of menopause.

J Sex Med

January 2025

Division of Female Pelvic Medicine and Reconstructive Surgery, The Christ Hospital, 6939 Cox Rd, Suite 271, Liberty Township, OH, United States.

Background: Genitourinary syndrome of menopause (GSM) is a prevalent condition with a constellation of symptoms including burning, dryness, dyspareunia, and irritative lower urinary tract symptoms that result from vulvovaginal atrophic changes. Though hormonal therapy is a mainstay of treatment in GSM, some patients may pursue nonhormonal therapies.

Aim: To determine the efficacy of radiofrequency ablation of the vaginal canal with the MorpheusV applicator in reducing the symptoms of GSM.

View Article and Find Full Text PDF

Purpose: The purpose of this study was to examine dimensions of the perioperative work environment and their associations with the operating room (OR) culture of safety and high-reliability characteristics.

Design: A predictive correlational design using a cross-sectional survey was used.

Methods: A convenience sample of perioperative nurses (N = 96) was used to evaluate strength of associations of their work environment with OR safety culture and high-reliability organizational culture.

View Article and Find Full Text PDF

Obesity Management in Women.

Nurs Clin North Am

December 2024

Obstetrics and Gynecology, Alum of the University of Louisville, 252 Whittington Parkway, Louisville, KY 40222, USA. Electronic address:

Article Synopsis
  • - Obesity is a chronic disease with various causes, and effective weight loss requires addressing all contributing factors.
  • - Women are particularly affected by obesity, especially from puberty, and face challenges due to metabolic and hormonal changes that make weight regain likely.
  • - Creating an energy deficit is crucial for treating obesity, with physical activity playing a key role in maintaining weight loss; medications can also help by reducing food intake if appropriate.
View Article and Find Full Text PDF

The purpose of this research was to test the impact of seeding a hydrogel chitosan scaffold (HCS) with human adipose-derived stem cells (hADSCs) under the influence of photobiomodulation (PBM) on the remodeling step on the wound repairing process in mice. Thirty mice were randomly assigned to five groups (n=6 per group ): The control group (group 1) consisted of mice without any intervention. In group 2, an HCS was implanted into the wound.

View Article and Find Full Text PDF

Invasive meningococcal disease (IMD) is an uncommon but serious and potentially fatal condition that can result in reduced life expectancy and a broad spectrum of sequelae, many of which may be lifelong and devastating for those who survive the acute disease period. In the United States of America (USA), vaccination is available against the five meningococcal serogroups (A, B, C, W, and Y), but meningococcal vaccination rates among healthy USA adolescents and individuals at high risk because of medical conditions are low, rendering them vulnerable to IMD and its sequelae. Despite the severity of the disease, the clinical impact and rates of IMD sequelae in the USA are poorly understood, as USA-specific data are limited, and the methodology of existing research is heterogenous.

View Article and Find Full Text PDF

Background: The literature on the ethics of biobanking often overlooks the practical operations of biobanks. The ethics of stewardship requires that biobank resources are used to conduct beneficial science. Networked biobanks have emerged to increase the scientific benefit of biobank resources, but little is known about whether and how operations of networking may accomplish this goal.

View Article and Find Full Text PDF
Article Synopsis
  • In 2005, routine vaccination against invasive meningococcal disease (IMD) was recommended for 11-12-year-olds and high-risk children aged 2-10, followed by a 2010 booster for 16-year-olds.
  • Optional vaccination against serogroup B was introduced in 2015, with a new combined vaccine (MenABCWY) for five serogroups available in 2023.
  • The review discusses how these policy changes aim to improve vaccination coverage and efficiency while addressing disparities in immunization.
View Article and Find Full Text PDF

Childhood health disparities by race have been found. Neighborhood disadvantage, which may result from racism, may impact outcomes. The aim of the study is to describe the distribution of mental health (MH) and developmental disabilities (DD) diagnosis across Child Opportunity Index (COI) levels by race/ethnicity.

View Article and Find Full Text PDF

Purpose: As population-based screening programs to identify genetic conditions in adults using genomic sequencing (GS) are increasingly available, validated patient-centered outcome measures are needed to understand participants' experience. We aimed to develop and validate an instrument to assess the perceived utility of GS in the context of adult screening.

Methods: Informed by a 5-domain conceptual model, we used a 5-step approach to instrument development and validation: (1) item writing, (2) cognitive testing, (3) pilot testing and item reduction, (4) psychometric testing, and (5) evaluation of construct validity.

View Article and Find Full Text PDF

Editorial: Cardiovascular diseases related to diabetes and obesity - volume IV.

Front Endocrinol (Lausanne)

August 2024

Pediatric Research Institute, Departments of Pediatrics, Radiation Oncology, Pharmacology and Toxicology, the University of Louisville School of Medicine, Louisville, KY, United States.

View Article and Find Full Text PDF

Purpose: Understanding drivers of antibiotic use is key to limiting the development of antimicrobial resistance. Outpatient antibiotic prescribing rates vary substantially across and within states. Kentucky is one of the highest prescribing states, and the southeastern region has rates that are drastically higher than the national average and urban areas of the state.

View Article and Find Full Text PDF

To test the hypothesized crucial role of microglia in the developmental refinement of neural circuitry, we depleted microglia from mice of both sexes with PLX5622 and examined the experience-dependent maturation of visual circuitry and function. We assessed retinal function, receptive field tuning of visual cortex neurons, acuity and experience-dependent plasticity. None of these measurements detectibly differed in the absence of microglia, challenging the role of microglia in sculpting neural circuits.

View Article and Find Full Text PDF
Article Synopsis
  • A 45-year-old woman with a history of alcoholism experienced a proximal humerus fracture and initially underwent surgery using a lateral locking plate but faced complications due to falls caused by delirium tremens.
  • After her condition worsened, she required revision surgery where the previous hardware was removed and a new fixation was done with the addition of a UV-activated intramedullary cement implant.
  • This case is notable as it is the first reported use of UV-activated cement to strengthen the fixation for such fractures, addressing issues of non-compliance that could lead to surgical failure.
View Article and Find Full Text PDF

Manganese is an essential element but can be neurotoxic if overexposed. Our previous study found that a higher level of manganese in nail biomarkers from children living near coal ash storage sites was associated with poorer neurobehavioral function. Children living near this type of pollution may be exposed to other metal neurotoxicants and a better understanding of manganese in the context of multiple exposures is needed.

View Article and Find Full Text PDF

Sexual violence (SV) can deeply impact victims' physical and psychosocial well-being. Yet many healthcare providers, including registered nurses (RNs), hesitate to screen patients due to a lack of confidence and knowledge. The SATELLITE Sexual Violence Assessment and Care Guide was developed to address this gap; however, the guide's educational effectiveness remained untested.

View Article and Find Full Text PDF

The Utility of BIS™ Monitoring in Anesthesia for Elderly Patients.

AANA J

June 2024

is the Director of Professional Practice, American Association of Nurse Anesthesiology, Rosemont, Illinois. Email:

Aging leads to anatomic and physiologic changes in the brain, making it more sensitive to the depressant effects of anesthetic medications and increasing the risk of postoperative neurocognitive complications such as postoperative delirium and postoperative cognitive dysfunction. This article explores the implications of anesthesia on elderly patients' brain health, emphasizing the heightened risk of postoperative neurocognitive disorders, and describes the BIS™ Monitoring System as a neuromonitoring tool for anesthesia professionals to assess the depth of anesthesia. The integration of the BIS Monitoring System into clinical practice can contribute to a more tailored and patient-centered approach to anesthesia management, ultimately improving perioperative outcomes and safety.

View Article and Find Full Text PDF

Purpose: Measuring the effects of genomic sequencing (GS) on patients and families is critical for translational research. We aimed to develop and validate an instrument to assess parents' perceived utility of pediatric diagnostic GS.

Methods: Informed by a 5-domain conceptual model, the study comprised 5 steps: (1) item writing, (2) cognitive testing, (3) pilot testing and item reduction, (4) psychometric testing, and (5) evaluation of construct validity.

View Article and Find Full Text PDF