420 results match your criteria: "The University of Kansas School of Medicine[Affiliation]"

Home- and community-based services (HCBS) are increasingly favored over nursing home care by older consumers and by policymakers. Consumer-reported unmet service needs in HCBS are important service quality and person-centeredness indicators. Yet, we know little about consumer-reported unmet needs among HCBS users.

View Article and Find Full Text PDF
Article Synopsis
  • Alcohol-related liver disease (ALD) is a growing public health issue, especially among people under 55, leading to an increase in alcohol-attributable deaths that are projected to rise further by 2030.
  • Data from the CDC revealed a significant increase in mortality rates, particularly in the 25-34 age group, with rates climbing from 3.9 per 100,000 in 1999 to an expected 14.4 per 100,000 by 2030.
  • This upward trend highlights the urgent need for public health interventions to address and reduce ALD mortality rates in younger populations.
View Article and Find Full Text PDF

Non-alcoholic liver disease (NAFLD) may be associated with cardiovascular diseases; however, only a few studies have analyzed this relationship. We aimed to assess the epidemiologic data and the association between NAFLD and acute myocardial infarction (AMI) in the United States. The National Inpatient Sample (NIS) database 2016-2019 was queried using ICD10-CM diagnostic codes to identify hospitalizations of AMI + NAFLD.

View Article and Find Full Text PDF

Racial Disparities in Inpatient Hospital Outcomes of Primary Sclerosing Cholangitis in United States: Nationwide Analysis.

Diagnostics (Basel)

November 2024

Parkview Cancer Institute, Advanced Interventional Endoscopy & Endoscopic Oncology (IOSE) Division, GI Oncology Program, 11104 Parkview Circle, Suite 310, Fort Wayne, IN 46845, USA.

Article Synopsis
  • Primary sclerosing cholangitis (PSC) is a liver disease linked to inflammatory bowel disease and can cause serious liver complications; this study investigates trends in healthcare usage and mortality related to PSC in the U.S. from 2008 to 2017.
  • The analysis of the Nationwide Inpatient Sample reveals that while hospital charges for PSC patients rose by 32.2%, the average length of hospital stays decreased during the study period, indicating changes in healthcare practices.
  • Additionally, there was a notable increase in the severity of illness and risk of death among PSC patients, with a rise in cases of hepatocellular carcinoma (HCC), while cases of cholangiocarcinoma (CCA) saw a decline.
View Article and Find Full Text PDF

Background: Left atrial appendage (LAA) occlusion (LAAO) is performed to prevent LAA thrombus in patients with atrial fibrillation (AF). The risk of device-related thrombus (DRT) on the atrial side of the LAAO device is approximately 4%. Identifying patients at high risk of DRT would enable closer surveillance and more-aggressive anticoagulation to prevent post-LAAO DRT-related stroke.

View Article and Find Full Text PDF

Background: The purpose of this study was to determine the clinical outcomes of mucous cystectomy and osteophytectomy using a random nonadvancement flap technique.

Methods: This was a therapeutic outcomes study of patients who underwent mucous cystectomy under local anesthesia by 1 of 2 hand fellowship-trained surgeons between 2012 and 2022. The key features of the surgical technique include designing a random nonadvancement flap with the cyst at its base; transecting the cyst pedicle as the flap is elevated; resecting the cyst wall from the undersurface of the reflected flap; decompressing the distal joint by removing marginal osteophytes; and insetting the flap without advancement.

View Article and Find Full Text PDF

Background/objectives: Predicting inpatient mortality for acute pancreatitis (AP) patients in the ICU is crucial for optimal treatment planning. This study aims to develop a concise risk score model for this purpose, enhancing the predictability and management of AP in ICU settings.

Methods: We included 380 patients in our training set.

View Article and Find Full Text PDF

We assessed the impact of frailty on outcomes of endoscopic retrograde cholangiopancreatography (ERCP) in the United States. The National Readmission Database (2016-2020) was used to identify index and 30-day ERCP readmissions, which were categorized into low-frailty, intermediate-frailty, and high-frailty groups based on the Hospital Frailty Risk Score (HFRS). Outcomes were then compared.

View Article and Find Full Text PDF

Safety and Efficacy of Endoscopic Submucosal Dissection for Rectal Neoplasms Extending to the Dentate Line: A Systematic Review and Meta-analysis.

J Clin Gastroenterol

October 2024

Department of Interventional Oncology and Surgical Endoscopy - IOSE, Peak Gastroenterology and Gastrocare Partners, Colorado Springs, CO.

Objective: Endoscopic submucosal dissection (ESD) is a superior, minimally invasive technique compared with other snare-based endoscopic resection techniques for rectal neoplasms extending to the dentate line (RNDLs). However, performing a successful ESD in the anal canal can be challenging due to vascularity and limited scope stability. In this meta-analysis, we aim to evaluate the safety and efficacy of ESD for RNDLs.

View Article and Find Full Text PDF

Background And Aims: Effect of underwater endoscopic submucosal dissection (UESD) on clinical outcomes as compared with conventional ESD (CESD) remains unclear. We conducted a meta-analysis of the available data.

Methods: Online databases were searched for studies comparing UESD with CESD for colorectal lesions.

View Article and Find Full Text PDF
Article Synopsis
  • Atrial fibrillation (AF) can weaken the left atrial appendage, increasing the risk of stroke, which can be measured through left atrial appendage emptying velocity (LAAev) via transesophageal echocardiogram (TEE).
  • A study evaluated factors that lead to reduced LAAev (<30 cm/s) in patients with AF, using logistic regression to create a risk prediction model called the CHIRPM score based on various clinical and echocardiographic traits.
  • The model was validated against a dataset, showing that both low and high CHIRPM scores significantly correlated with LAAev levels, offering a new way to assess stroke risk among individuals with AF.
View Article and Find Full Text PDF

Introduction: Effective, evidence-based obesity treatment is needed, which often involves use of anti-obesity medications (AOMs). Data on the breadth and quality of guideline-directed obesity treatment implementation in primary care remain limited. This study aimed to assess primary care clinicians' agreement with and knowledge of guideline-directed obesity treatment, as well as to assess the health status of persons with obesity and their use of AOMs.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of standard ECG criteria for diagnosing left ventricular hypertrophy (LVH) in patients with left bundle branch block (LBBB) and finds that QRS duration is a more reliable indicator than traditional criteria.
  • Researchers included 413 adults with LBBB and compared the predictive power of QRS duration to established LVH criteria by assessing LV mass and volume through echocardiograms.
  • Results showed that QRS duration had higher diagnostic accuracy for LVH and dilation in both men and women compared to any other ECG criteria, establishing it as a better predictor in these patients.
View Article and Find Full Text PDF

Impact of GLP-1 Receptor Agonists in Gastrointestinal Endoscopy: An Updated Review.

J Clin Med

September 2024

Gastroenterology Unit, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become one of the most popular medications for patients with diabetes and obesity. Due to their effects on gut motility via central or parasympathetic pathways, there have been concerns about an increased incidence of retained gastric contents and risk of aspiration in the perioperative period. Hence, the American Society of Anesthesiologists (ASA) recommends holding GLP-1 RAs on the procedure day or a week before the elective procedure based on the respective daily or weekly formulations, regardless of the dose, indication (obesity or diabetes), or procedure type.

View Article and Find Full Text PDF
Article Synopsis
  • Acute necrotizing pancreatitis is a serious condition that challenges healthcare providers due to potential complications, with various necrosectomy procedures available but no clear consensus on the best timing for the operation.
  • A national study analyzed data from 2016-2019 to assess the effects of timely necrosectomy (within 48 hours) vs. delayed necrosectomy on patient outcomes, focusing on readmission rates, healthcare use, and mortality.
  • Results showed that early necrosectomy had lower readmission rates, reduced need for mechanical ventilation and septic shock, decreased in-hospital mortality, and resulted in lower healthcare costs and shorter hospital stays compared to delayed interventions.
View Article and Find Full Text PDF
Article Synopsis
  • In 2013, the SPIRIT group introduced guidelines to enhance reporting quality in randomized controlled trials (RCTs), specifically targeting studies on endoscopic colorectal cancer screening.
  • A review of five RCTs showed adherence to SPIRIT guidelines between 82.4% to 92.2%, with significant gaps in trial registration and informed consent reporting.
  • Overall, 37% of participants invited to screening actually underwent the procedure, highlighting discrepancies in protocol adherence, particularly with one trial showing notably lower rates.
View Article and Find Full Text PDF

Background: Various endoscopic techniques are employed to achieve biliary cannulation when confronted with difficult biliary access. Every procedure carries its own risk in terms of bleeding, infection, pancreatitis, and cholangitis. Our meta-analysis aimed to compare pre-cut papillotomy and endoscopic ultrasound (EUS)-rendezvous in terms of technical success rates, and post-procedure pancreatitis and bleeding.

View Article and Find Full Text PDF

Pancreatic cancer is a rare but lethal cancer due to its biologically aggressive nature, advanced stage at the time of diagnosis, and poor response to oncologic therapies. The risk of pancreatic cancer is significantly higher to 5% in certain high-risk individuals with inherited genetic susceptibility. Screening for pancreatic cancer in these individuals from high-risk groups can help with the early detection of pancreatic cancer as well as the detection of precursor lesions leading to early surgical resection and improved overall outcomes.

View Article and Find Full Text PDF