792 results match your criteria: "The University of Iowa Hospitals and Clinics.[Affiliation]"

Background: Previous studies have shown that when thrombectomy has failed, rescue intracranial stenting is associated with better clinical outcomes compared with failed reperfusion. However, comparative data regarding stent type are lacking.

Objective: To compare the procedural and clinical outcomes of balloon-mounted stents (BMS) with those of self-expandable stents (SES).

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We present a case of Acute Angle-Closure Crisis (AACC) precipitated by primary transient psychogenic polydipsia; we believe that our case is the first of its kind to be reported. A 74-year-old male presented to the emergency department with altered mental status due to acute-onset hyponatremia. Six days after admission, the patient noticed painful loss of vision in his right eye and an ipsilateral headache lasting 10-15 minutes.

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The hypercapnic environment on the International Space Station (ISS): A potential contributing factor to ocular surface symptoms in astronauts.

Life Sci Space Res (Amst)

February 2025

Center for Space Medicine, Baylor College of Medicine, Houston, Texas, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas, United States; University of Texas MD Anderson Cancer Center, Houston, Texas, United States; Texas A&M College of Medicine, Texas, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, United States.

With increasing advancements and efforts towards space exploration, there is a pressing need to understand the impacts of spaceflight on astronauts' health. Astronauts have reported signs and symptoms of dry eye disease upon traveling to the International Space Station (ISS), thus necessitating an evaluation of the factors that contribute to the onset of spaceflight associated dry eye disease. Prior literature describes the hypercapnic environment of the ISS; however, the link between the high CO levels and astronauts' symptoms of dry eye disease remains unexplored.

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Left homonymous hemianopsia secondary to intravenous tenecteplase.

Can J Ophthalmol

January 2025

Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, USA; University of Texas Medical Branch, Galveston, Texas, USA; Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA; Weill Cornell Medicine, New York, New York, USA; University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Texas A&M College of Medicine, Bryan, Texas, USA; The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

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The National Aeronautics and Space Administration (NASA) in the United States has been studying a fascinating and unique constellation of neuro-ophthalmic findings collectively known as Spaceflight Associated Neuro-Ocular Syndrome (SANS). SANS is unique to the space environment of microgravity and produces novel physiological and pathological findings that have no direct terrestrial equivalent. The neuro-ophthalmic phenomenon is a major physiologic barrier to future planetary spaceflight.

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Pleomorphic adenoma of the lacrimal gland (PALG) is a benign neoplasm typically presenting with gradual, painless globe displacement and/or lid swelling. We report an atypical case of PALG in a 53-year old male presenting acutely, mimicking orbital cellulitis. Imaging demonstrated an extraconal rim-enhancing soft-tissue lesion medial to the left lacrimal gland, involving superior rectus and levator palpebrae superioris.

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Assessing the Risk of Kidney Stone Development in Patients With Idiopathic Intracranial Hypertension Treated With Carbonic Anhydrase Inhibitors.

J Neuroophthalmol

December 2024

College of Medicine (JM, AGL), Texas A&M University, Houston, Texas; Department of Ophthalmology (SAA, OAD, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (OAD), Hashemite University, Amman, Jordan; Department of Ophthalmology (AL, AGL), Cullen Eye Institute, Baylor College of Medicine, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas MD Anderson Cancer Center, Houston, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Background: The prevalence of idiopathic intracranial hypertension (IIH) is rising with the global obesity epidemic. Carbonic anhydrase inhibitors (CAIs), such as acetazolamide, have been shown to be effective in IIH but can also lead to kidney stone formation. This study evaluates the risk of kidney stone development in patients with IIH treated with CAIs.

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Purpose: Herpes zoster ophthalmicus (HZO) following COVID-19 vaccination has been reported previously but the clinical characteristics, onset, treatment, and outcomes of these cases have not been previously systematically reviewed.

Methods: A systematic review, guided by PRISMA guidelines, surveyed PubMed and Embase databases from April 2021 to June 2023 for case reports and series detailing HZO following COVID-19 vaccination. Studies excluded were abstracts, reviews, and clinical trials.

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Ophthalmoplegia in Seropositive Myasthenia Gravis and Concomitant Seropositive Anti-GQ1b Disease.

J Neuroophthalmol

December 2024

Departments of Neurology and Neuro-Ophthalmology (AV), Valley Hospital Medical Center, Las Vegas Neurology Center, Las Vegas, Nevada; University of Nevada Las Vegas School of Medicine (CD), Las Vegas, Nevada; Departments of Neurology (CN, PJ), Valley Hospital Medical Center, Las Vegas Neurology Center, Las Vegas, Nevada; McGovern Medical School (MYZ), University of Texas at Houston Health Science Center, Houston, Texas; Department of Ophthalmology (RI), University of Texas Medical Branch, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (SAA, AGL), Houston Methodist Hospital, Houston, Texas; Ophthalmology (AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Ophthalmology (AGL), UTMB Galveston, Texas A and M College of Medicine, and the UT MD Anderson Cancer Center, Houston, Texas; and Ophthalmology (AGL), Baylor College of Medicine, The University of Buffalo, Buffalo, New York, and the University of Iowa Hospitals and Clinics (AGL), Houston, Texas.

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Antiphospholipid Antibody Syndrome: Concurrent Retinal Vein Occlusion and Homonymous Hemianopia From Ischemic Stroke.

J Neuroophthalmol

December 2024

John Sealy School of Medicine (HJY), University of Texas Medical Branch, Galveston, Texas; Department of Ophthalmology and Visual Sciences (CK), University of Texas Medical Branch, Galveston, Texas; Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program (TAN, GD), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (SAA, OAD, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (OAD), Hashemite University, Amman, Jordan; Department of Ophthalmology (AGL), Cullen Eye Institute, Baylor College of Medicine, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas MD Anderson Cancer Center, Houston, Texas; Texas A&M College of Medicine (AGL), Bryan, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.

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Influence of Common Medications on Diabetic Macular Edema in Type 2 Diabetes Mellitus.

Ophthalmol Retina

December 2024

Ruiz Department of Ophthalmology and Visual Science, University of Texas Health Science Center, Houston, Texas. Electronic address:

Purpose: This study aimed to assess the impact of systemic medications, including glucagon-like peptide-1 receptor agonists (GLP-1 RAs), fenofibrates, thiazolidinediones (TZDs), and calcium channel blockers (CCBs), on the risk of developing diabetic macular edema (DME) in patients with type 2 diabetes mellitus (T2DM).

Design: A retrospective cohort study was conducted using electronic medical records (EMR) data from the TriNetX health research network, covering a period from October 2004 to 2024.

Participants: The study population comprised patients diagnosed with T2DM who were newly initiated on GLP-1 RAs, fenofibrates, TZDs, or CCBs.

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Visual processing involves numerous neuro-ophthalmic pathways that enable humans to perceive and interact with the world. These visual pathways can negatively impact visual perception and decision-making. The Vestibulo-Ocular Reflex (VOR) is a compensatory mechanism that stabilizes gaze on a target during head movement, such as running or turning.

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Purpose Of Review: Spaceflight-associated neuro-ocular syndrome (SANS) encompasses a unique constellation of neuro-ocular findings in astronauts, including optic disc edema (ODE), globe flattening, chorioretinal folds, and hyperopic refractive shift. Although there are numerous neuro-ocular findings in SANS, the purpose of this review is to describe the novel, emerging concepts of the pathogenesis for the ODE specifically in SANS.

Recent Findings: While the initial hypotheses on the pathogenesis of ODE in SANS focused on possible elevated intracranial pressures (i.

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Dural arteriovenous fistulas (DAVFs) are rare but significant intracranial vascular malformations that are usually idiopathic and can lead to severe complications like venous hypertension and intracranial hemorrhage. We present 2 cases of DAVF occurring after venous sinus stenting (VSS) for presumed idiopathic intracranial hypertension (IIH) in a 51-year-old and a 52-year-old female. In both patients, Cognard type 1 DAVF was detected by Catheter angiography and successfully obliterated with Onyx™ embolization.

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In post-liver transplant patients, esophagitis presents a diagnostic and management challenge due to the potential for opportunistic infections. This case describes a 59-year-old female with primary sclerosing cholangitis who underwent orthotopic liver transplantation six years prior. She presented with dysphagia, and her medical history included immunosuppression with prednisone, tacrolimus, and mycophenolate and a history of achalasia treated with esophageal peroral endoscopic myotomy.

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In this study, it was aimed to assess the microstructural changes in the main central auditory pathway in cases with subjective tinnitus. In total, 101 subjects (52 cases with bilateral subjective non-pulsatile tinnitus and 49 healthy cases as the control group) were included in the study. Participants underwent pure tone audiogram and Diffusion Tensor Imaging-Magnetic Resonance Imaging (DTI-MRI) examination with a 3 Tesla MRI device.

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Spaceflight associated dry eye syndrome (SADES): Radiation, stressors, and ocular surface health.

Life Sci Space Res (Amst)

November 2024

Center for Space Medicine, Baylor College of Medicine, Houston, TX, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, TX, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, TX, United States; University of Texas MD Anderson Cancer Center, Houston, TX, United States; Texas A&M School of Medicine, Bryan, TX, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA, United States.

Article Synopsis
  • Crewed spaceflight missions present health risks, notably changes to astronauts' tear film lipid layer, which can lead to complications like dry eye syndrome.
  • The review focuses on existing studies related to tear film biophysics and the specific symptoms associated with spaceflight-associated dry eye syndrome (SADES).
  • The insights gained can help address ocular health during long-duration missions, such as those planned for the Moon and Mars.
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Objective: Macular retinal nerve fibre layer (mRNFL) and ganglion cell-inner plexiform layer thickness (GC-IPL) measurements are important markers of diabetic retinal neurodegeneration (DRN). In this cross-sectional study, we aimed to quantify the contribution of total retinal thickness (TRT) and other factors in the variation of mRNFL and GC-IPL thickness among participants with diabetes.

Methods And Analysis: We used macular-centred spectral domain-optical coherence tomography scans from participants with diabetes in the UK Biobank.

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Background And Objectives: First-line therapy for most intracranial dural arteriovenous fistulas (dAVFs) is endovascular embolization, but some require microsurgical ligation due to limited endovascular accessibility, anticipated lower cure rates, or unacceptable risk profiles. We investigated the most common surgically treated dAVF locations and the approaches and outcomes of each.

Methods: The Consortium for Dural Arteriovenous Fistula Outcomes Research database was retrospectively reviewed.

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Poststrangulation hypoxic-ischemic encephalopathy.

Can J Ophthalmol

October 2024

Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA; Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA; Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, USA; University of Texas MD Anderson Cancer Center, Houston, TX, USA; Texas A&M College of Medicine, Bryan, TX, USA; The University of Iowa Hospitals and Clinics, Iowa City, IA, USA. Electronic address:

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Transient Eruption of Verrucous Keratoses During Encorafenib Therapy: Adverse Event or Paraneoplastic Phenomenon?

Cutis

September 2024

Alex A. Marti is from the Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City. Drs. Willis and Liu are from the Department of Dermatology, The University of Iowa Hospitals and Clinics, Iowa City.

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