844 results match your criteria: "The University of Iowa Hospitals[Affiliation]"
Safety protocols, precautions, and countermeasures aboard the International Space Station (ISS) to prevent ocular injury.
Surv Ophthalmol
September 2024
Center for Space Medicine, Baylor College of Medicine, Houston, Texas, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas, United States; University of Texas MD Anderson Cancer Center, Houston, Texas, United States; Texas A&M College of Medicine, Texas, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States.
Article Synopsis
- * To protect crew members from ocular injuries, the ISS uses ophthalmic medications, environmental support systems, radiation protection, and conducts thorough preflight screenings.
- * Future missions to the Moon and Mars, including NASA's Gateway Program, will face new challenges for eye health, necessitating ongoing research and improvements in safety protocols for astronauts in extraterrestrial environments.
Nasal Hemianopic Junctional Scotoma of Traquair Secondary to Chordoma.
J Neuroophthalmol
September 2024
School of Medicine (RS), Baylor College of Medicine, Houston, Texas; Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program (TAN), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (SAA, OAD, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (OAD), Hashemite University, Amman, Jordan; Department of Ophthalmology (AGL), Cullen Eye Institute, Baylor College of Medicine, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Ophthalmology, Texas A&M College of Medicine (AGL), Bryan, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Artificial intelligence in corneal diseases: A narrative review.
Cont Lens Anterior Eye
December 2024
The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, TX, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, TX, United States; University of Texas MD Anderson Cancer Center, Houston, TX, United States; Texas A&M College of Medicine, TX, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA, United States.
Article Synopsis
- Corneal diseases are increasingly problematic, especially in areas with limited eye care resources, but AI can help automate their diagnosis and management.
- This review highlights AI’s effectiveness in diagnosing various corneal conditions, showing it often surpasses human accuracy by using combined imaging and clinical data.
- Although there are challenges like diverse patient populations and the complexity of AI models, advancements in explainable AI and better data handling can improve the situation.
Delayed Diagnosis of Thymoma in Ocular Myasthenia Gravis.
J Neuroophthalmol
September 2024
Texas A and M College of Medicine (LN, AGL), Bryan, Texas; Department of Ophthalmology (LH, AGL), University of Texas Medical Branch, Galveston, Texas; Department of Ophthalmology (MP, CC, PWM, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; University of Texas MD Anderson Cancer Center (AGL), Houston, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Simultaneous Fulminant Intracranial and Systemic Hypertension.
J Neuroophthalmol
September 2024
Texas Tech University Health Sciences Center School of Medicine (HDM), Lubbock, Texas; Texas A&M School of Engineering Medicine (ZIR), Houston, Texas; Texas A&M School of Medicine (ZIR, AGL), Bryan, Texas; Department of Ophthalmology (NAL, PADS, PWM, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas Medical Branch, Galveston, Texas; University of Texas MD Anderson Cancer Center (AGL), Houston, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals, Iowa City, Iowa.
Quantification of First Metatarsal Joint Surface Interactions in Hallux Rigidus Using Distance and Coverage Mapping: A Case-Control Study.
Foot Ankle Int
September 2024
Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Background: Weightbearing cone-beam computed tomography (WBCT) has proven useful for analysis of structural changes of the foot and ankle when compared to conventional radiographs. WBCT allows for extraction of distance and coverage mapping metrics, which may provide novel insight into hallux rigidus (HR). This study retrospectively assessed HR joint space using distance and coverage mapping in a case-control study.
View Article and Find Full Text PDFImpedance threshold device as a countermeasure for spaceflight associated neuro-ocular syndrome (SANS): Mitigating mechanisms in proposed pathophysiology.
Life Sci Space Res (Amst)
August 2024
Center for Space Medicine, Baylor College of Medicine, Houston, Texas, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas, United States; University of Texas MD Anderson Cancer Center, Houston, Texas, United States; Texas A&M College of Medicine, Bryan, Texas, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States. Electronic address:
Article Synopsis
- - Long-duration spaceflight (LDSF) poses specific health risks, notably Spaceflight Associated Neuro-ocular Syndrome (SANS), linked to changes in fluid dynamics and increased pressure in the brain due to microgravity.
- - SANS is unique to space environments, as there is no equivalent condition on Earth, although some studies attempt to simulate space conditions through bed rest and head-down tilting.
- - Proposed solutions to combat SANS include using thigh cuffs for blood flow regulation and devices like the impedance threshold device (ITD) to help reduce intracranial pressure.
Lower body negative pressure as a research tool and countermeasure for the physiological effects of spaceflight: A comprehensive review.
Life Sci Space Res (Amst)
August 2024
Center for Space Medicine, Baylor College of Medicine, Houston, TX, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, TX, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, TX, United States; University of Texas MD Anderson Cancer Center, Houston, TX, United States; Texas A&M College of Medicine, TX, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA, United States. Electronic address:
Article Synopsis
- Lower Body Negative Pressure (LBNP) helps shift blood from the upper body to the lower body, potentially helping astronauts deal with fluid redistribution effects in space.
- Over the past 50 years, advancements in LBNP technology have increased our understanding of how spaceflight affects various bodily systems, particularly in reducing bone loss.
- This study aims to review the historical development of LBNP and its potential uses in addressing the diverse physiological challenges astronauts face, while advocating for its broader application in ensuring astronaut health during space missions.
Coordinated lunar time (LTC): Implications of a lunar-centric time zone on astronaut health and space medicine.
Life Sci Space Res (Amst)
August 2024
Center for Space Medicine, Baylor College of Medicine, Houston, TX, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, TX, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, TX, United States; University of Texas MD Anderson Cancer Center, Houston, TX, United States; Texas A&M College of Medicine, TX, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA, United States.
Article Synopsis
- Lunar exploration is crucial for advancing science, economic growth, and the potential for humans to live on multiple planets.
- On April 2, 2024, the Biden-Harris Administration emphasized the need for time standards beyond Earth, proposing the idea of Coordinated Lunar Time (CLT) for the moon.
- CLT would enhance astronaut health and mission efficiency, but requires international cooperation and agreements for its implementation.
Biophysics of ophthalmic medications during spaceflight: Principles of ocular fluid dynamics and pharmacokinetics in microgravity.
Life Sci Space Res (Amst)
August 2024
Texas A&M School of Medicine, Bryan, TX, United States; Center for Space Medicine, Baylor College of Medicine, Houston, Texas, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas, United States; University of Texas MD Anderson Cancer Center, Houston, Texas, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States. Electronic address:
Article Synopsis
- As space travel becomes more accessible, it's important to address eye diseases that may arise in these unique environments.
- This paper examines the treatment methods for ocular diseases, focusing on topical eye drops and intravitreal injections, and how microgravity affects their administration.
- It aims to clarify the relationship between drug delivery, fluid dynamics, and human physiology in zero gravity to develop better solutions for those facing these challenges in space.
Imaging in spaceflight associated neuro-ocular syndrome (SANS): Current technology and future directions in modalities.
Life Sci Space Res (Amst)
August 2024
Human-Machine Perception Laboratory, Department of Computer Science and Engineering, University of Nevada, Reno, Reno, Nevada, United States; Center for Space Medicine, Baylor College of Medicine, Houston, Texas, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, 6560 Fannin St #450, Houston, Texas 77030, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas, United States; University of Texas MD Anderson Cancer Center, Houston, Texas, United States; Texas A&M School of Medicine, Bryan, Texas, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States. Electronic address:
Article Synopsis
- * SANS is characterized by symptoms such as swelling of the optic disc, changes in eye shape, and retinal abnormalities, but its exact cause is still not fully understood and may involve fluid shifts in microgravity and other factors.
- * Advanced imaging techniques, including MRI and optical coherence tomography, are crucial for diagnosing and monitoring SANS, and new methods like near-infrared spectroscopy and diffusion tensor imaging could enhance future research and analysis.
Neurostimulation as a technology countermeasure for dry eye syndrome in astronauts.
Life Sci Space Res (Amst)
August 2024
Center for Space Medicine, Baylor College of Medicine, Houston, Texas, United States; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, United States; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, United States; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York, United States; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas, United States; University of Texas MD Anderson Cancer Center, Houston, Texas, United States; Texas A&M College of Medicine, Texas, United States; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States.
Article Synopsis
- Dry eye syndrome (DES) affects up to 30% of astronauts on the International Space Station due to changes in fluid dynamics caused by microgravity, increasing the risk of corneal abrasions and impairing visual function.
- Current treatments, like artificial tears, face challenges such as fluid dynamics within containers and contamination risks, highlighting the need for better solutions.
- Neurostimulation presents a promising new method for managing DES symptoms by using electrical signals to improve neural function, making it a focus for future space missions such as those to the Moon and Mars.
Cryptococcal Meningitis Presenting With Headache and Visual Aura.
J Neuroophthalmol
August 2024
Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program (TAN), New York City, New York; Department of Ophthalmology (SAA, OAD, NARL, AGL), Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas Medical Branch, Galveston, Texas; University of Texas MD Anderson Cancer Center (AGL), Houston, Texas; Texas A&M College of Medicine (AGL), Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Cerebellopontine angle compression with follicular dendritic cell sarcoma of the skull base.
Can J Ophthalmol
December 2024
Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, USA; Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, USA; Department of Ophthalmology, University of Texas MD Anderson Cancer Center, Houston, TX, USA; Texas A&M College of Medicine, Bryan, TX, USA; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA, USA. Electronic address:
Amyloidosis with optic perineuritis masquerading as giant cell arteritis.
Can J Ophthalmol
December 2024
Weill Cornell Medicine, New York, NY; University of Texas Medical Branch, Galveston, TX; University of Texas MD Anderson Cancer Center, Houston, TX; Texas A and M College of Medicine, Bryan, TX; The University of Iowa Hospitals and Clinics, Iowa City, IA. Electronic address:
Optic neuritis in retinitis pigmentosa.
Can J Ophthalmol
December 2024
Blanton Eye Institute, Houston Methodist Hospital, Houston, TX; Cullen Eye Institute, Baylor College of Medicine, Houston, TX; Weill Cornell Medicine, New York, NY; University of Texas MD Anderson Cancer Center, Houston, TX; Texas A&M College of Medicine, Bryan, TX; The University of Iowa Hospitals and Clinics, Iowa City, IA; Sam Houston State College of Osteopathic Medicine, Houston, TX. Electronic address:
Reversible Nyctalopia and Bilateral Optic Neuropathy due to Combined Vitamin A, Zinc, and Copper Deficiency: A Case Report.
Case Rep Ophthalmol
July 2024
Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA.
Article Synopsis
- A rare case of combined nutritional deficiencies—including vitamin A, zinc, and copper—was reported to cause bilateral central vision loss and nyctalopia in a patient post-bariatric surgery and alcohol use.
- *The patient's vision significantly improved within one month after starting vitamin and mineral supplementation.
- *Clinicians should be aware of the potential for similar vision loss from nutritional deficiencies, especially with increasing rates of bariatric surgery and alcohol consumption.
The natural and artificial intraocular lens in spaceflight.
Eye (Lond)
November 2024
Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA.
The spaceflight contrast sensitivity hypothesis and its role to investigate the pathophysiology of spaceflight-associated neuro-ocular syndrome.
Front Ophthalmol (Lausanne)
September 2023
Center for Space Medicine, Baylor College of Medicine, Houston, TX, United States.
Obesity is associated with muscle atrophy in rotator cuff tear.
BMJ Open Sport Exerc Med
June 2024
Orthopaedics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Article Synopsis
- The study aimed to investigate how Body Mass Index (BMI) affects muscle atrophy in patients with rotator cuff tears.
- Using MRI data from two different patient groups, researchers found that higher BMI is linked to an increased likelihood of muscle atrophy in these individuals.
- Specifically, each 5 kg/m increase in BMI correlated with a 21% rise in muscle atrophy odds for any tear size and 36% for full-thickness tears, indicating a significant relationship that warrants further research.
Intrasaccular Flow Disruption: Examining Global Access and Research Trends.
World Neurosurg
September 2024
Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.
Article Synopsis
- * The WEB has significantly more citations (mean 35.6) compared to other intrasaccular flow disruptors (mean 4.24), with most studies being retrospective reviews and a noticeable lack of contributions from African authors.
- * The analysis highlights that leading countries in WEB research (like France) differ from those contributing to other flow disruptors (like Germany), indicating a skew in global research collaboration and production, primarily concentrated in Europe and North America.
Classifying and quantifying changes in papilloedema using machine learning.
BMJ Neurol Open
June 2024
Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Machine learning (ML) can differentiate papilloedema from normal optic discs using fundus photos. Currently, papilloedema severity is assessed using the descriptive, ordinal Frisén scale. We hypothesise that ML can quantify papilloedema and detect a treatment effect on papilloedema due to idiopathic intracranial hypertension.
View Article and Find Full Text PDFQuantum machine learning in ophthalmology.
Eye (Lond)
October 2024
Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA.
Corneal wound healing in spaceflight: implications of microgravity-induced molecular signaling modulations for corneal health.
Eye (Lond)
October 2024
Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA.