883 results match your criteria: "The University of Glasgow Dental Hospital & School[Affiliation]"

In the UK Oral and Maxillofacial Surgery (OMFS) and Oral Surgery (OS) are distinct specialties governed respectively by the General Medical Council (GMC) and General Dental Council (GDC) respectively. There has always been overlap of training and care between both specialties. The OMFS curriculum was updated in 2021 and the Oral Surgery Curriculum in 2023.

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In 2008 the Postgraduate Medical Education and Training Board (PMETB) Review of Oral and Maxillofacial Surgery (OMFS) recommended that OMFS specialty training should start with second-degree studies. This recommendation has not yet happened. Currently, no OMFS controlled places at medical/dental schools are directly linked to OMFS Specialty Training (ST) posts.

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This study was carried out to compare the stability of Le Fort I maxillary advancement between the surgery-first approach (SFA) and the orthodontics-first approach (OFA), and to evaluate the impact of the quality of postoperative occlusion on maxillary stability. In total, 26 patients (13 SFA and 13 OFA) were included in this study. Cone beam computed tomography (CBCT) scans taken at T0 (1 week before surgery), T1 (1 week after surgery), and T2 (6 months after surgery) were used for the assessment of maxillary stability.

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Aims The aim of this study was to evaluate the severity of chronic obstructive pulmonary disease (COPD) using the computed tomography severity index (CTSI) and the modified CTSI (MCTSI) and to assess their correlation with clinical outcome measures. Additionally, the study aimed to compare the diagnostic performance of these indices in predicting moderate to severe COPD, based on patient outcomes. Materials and methods In this prospective study, conducted between November 2023 and March 2024, two radiologists, blinded to clinical outcomes, independently assessed CTSI and MCTSI.

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This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional characterization of mouse and human dendritic cells (DC) from lymphoid organs, and various nonlymphoid tissues. Within this article, detailed protocols are presented that allow for the generation of single-cell suspensions from human nonlymphoid tissues including lung, skin, gingiva, intestine as well as from tumors and tumor-draining lymph nodes with a subsequent analysis of dendritic cells by flow cytometry. Further, prepared single-cell suspensions can be subjected to other applications including cellular enrichment procedures, RNA sequencing, functional assays, etc.

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Background: The facial landmark annotation of 3D facial images is crucial in clinical orthodontics and orthognathic surgeries for accurate diagnosis and treatment planning. While manual landmarking has traditionally been the gold standard, it is labour-intensive and prone to variability.

Objective: This study presents a framework for automated landmark detection in 3D facial images within a clinical context, using convolutional neural networks (CNNs), and it assesses its accuracy in comparison to that of ground-truth data.

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Background Sepsis is a potentially fatal condition that necessitates prompt identification and assessment of its severity for effective management. However, evaluating sepsis severity using the Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores can be complex and costly. This study aimed to assess the association between neutrophil-to-lymphocyte ratio (NLR) and sepsis severity, as well as the role of NLR as a predictive indicator of sepsis severity in ICU patients.

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The Correlation Between Static and Dynamic Facial Asymmetry in Unilateral Cleft Lip and Palate.

Cleft Palate Craniofac J

November 2024

Oral and Maxillofacial Surgery, Scottish Craniofacial Research Group, Glasgow University Dental Hospital and School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Objective: Assess the relationship between static and dynamic facial asymmetry in unilateral cleft lip and palate during maximum smile.

Design: Retrospective cross-sectional study.

Setting: Multidisciplinary dentofacial planning clinic.

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Article Synopsis
  • Approximately 65 million people experience mild traumatic brain injury (mTBI) each year, and fatigue is a significant symptom affecting many of them.
  • The CRASH-3 trial studied the effects of tranexamic acid (TXA) on extreme fatigue in mTBI patients, finding that TXA did not significantly reduce fatigue compared to a placebo group.
  • The results suggest that further research is necessary due to limitations such as non-prespecified analyses and the methods of measuring fatigue, indicating the need for follow-up studies to confirm these findings.
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  • Antibiotic-associated diarrhea (AAD) commonly occurs due to antibiotic treatments disrupting gut microbiota, prompting research into the effectiveness of probiotics to prevent this issue.
  • The study aimed to evaluate how effective probiotics are in reducing AAD symptoms in adults compared to a placebo, enrolling 340 participants across various hospitals.
  • Results showed that the probiotic group had a significantly lower incidence of AAD (18.23%) compared to the placebo group (31.17%), indicating that probiotics may be beneficial in preventing this complication.
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  • This study examined the relationship between facial fractures and traumatic brain injuries in 492 polytrauma patients admitted to an emergency department over four years.
  • The results showed a significant association between facial fractures and brain injuries, with the zygoma bone being the most commonly fractured and subdural hematomas being the most frequent brain injury in patients with facial fractures.
  • Although both groups were similar in demographics and trauma causes, those with facial fractures had notably higher rates of severe brain injuries and were more likely to require intensive care.
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The Effect of Therapeutic Exercise and Local Cryotherapy on Lower Limb Enthesitis in Non-Radiographic Axial Spondyloarthritis: A Case Report.

J Pers Med

September 2024

Research Laboratory in Biomechanics, Rehabilitation and Ergonomics, IRCCS, Istituto Auxologico Italiano, San Giuseppe Hospital, 28824 Verbania, Italy.

Background: Enthesitis is a common feature of spondyloarthritis and can severely impair the patient's quality of life. International guidelines recommend multidisciplinary management of this condition, combining physical and pharmacological interventions. In this case report, we demonstrate clinical and ultrasonographic improvements by prescribing local cryotherapy and therapeutic exercise alone in an adult woman with non-radiographic axial SpA (nRX-AxSpA) complaining of heel enthesitis.

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  • - The study examines COVID-19 patients in ICUs in Pakistan from March 2020 to June 2023, focusing on the prevalence and outcomes of secondary fungal infections among 636 hospitalized patients.
  • - Results show that most patients were over 50 years old, with diabetes being the most common co-morbidity; 63 fungal infections occurred in 53 patients, mainly linked to the use of mechanical ventilation.
  • - The overall mortality rate was 4.9%, with secondary fungal infections significantly increasing the risk; the study emphasizes the need to monitor key factors to improve patient outcomes in future cases.
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  • The 2022 guidelines for fall prevention recommend assessing sensory functions like dizziness, vision, and hearing, but these factors aren't incorporated in current falls risk evaluation tools.
  • A study analyzed data from elderly patients assessed in an emergency department to explore how these sensory impairments might affect falls risk.
  • Findings indicated that most patients fell into high or low-risk categories, highlighting the need to adjust criteria for intermediate risk, particularly since hearing loss and dizziness were linked more strongly to fall incidents than vision or balance.
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  • The study aimed to evaluate hearing outcomes at 24 months for infants with mild congenital cytomegalovirus (cCMV) infection, comparing those who received antiviral treatment to those who did not.
  • Utilizing data from the European Registry of Children with cCMV, researchers included infants diagnosed with cCMV early in life, who had normal physical exams and mild imaging findings.
  • Results showed that 34.7% of the 196 participants received antiviral treatment, but there was no significant difference in hearing loss prevalence between treated (4.6%) and untreated groups (6.3%) after two years.
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  • * Recent efforts to stop smoking haven't been put into action yet, and it’s important to see what could happen if smoking rates stay the same or improve.
  • * Researchers used models to predict health outcomes by 2050 based on different scenarios of smoking rates, showing that cutting smoking could greatly improve health and life expectancy.
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3D Head Shape Feature Analysis of Zika-Infected Children.

Viruses

September 2024

Dental Hospital School, College of MVLS, University of Glasgow, Glasgow G2 3JZ, UK.

Article Synopsis
  • Congenital Zika syndrome (CZS) is a condition caused by Zika virus infection during pregnancy, leading to birth defects like small head size (microcephaly).
  • The study looked at 3D images of the heads of babies with CZS and compared them to babies without the infection to find differences in size and shape.
  • Researchers found that using a specific measurement called the head height to head circumference ratio (HH/HC) is more effective for diagnosing CZS than the usual method of just measuring head size.
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The British Association of Oral and Maxillofacial Surgeons (BAOMS) Quality and Outcomes in Oral and Maxillofacial Surgery (QOMS) reconstructive audit aims to provide surgical teams with risk adjusted comparative performance data. The goal is to enable surgeons to optimise surgical pathways. Risk adjustment requires that data on appropriate predictive variables are collected.

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Objective: To assess research trends and publication patterns of literature related to presurgical infant orthopaedics (PSIO) through a bibliometric analysis of the top 100 most-cited articles.

Material And Methods: The top 100 most-cited articles were identified in the Web of Science (WoS) database using search terms related to PSIO on April 23, 2024, without any restrictions to study design, publication date and language. Standard information about each study was extracted.

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  • Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
  • In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
  • There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
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According to the European Union (EU) Directive 2005/36, the medical specialty of oral and maxillofacial surgery (OMFS) exists with two possible formats: dual degree OMFS called Dental, Oral and Maxillofacial Surgery (DOMFS) - basic medical and basic dental training and single medical degree Maxillofacial Surgery (MFS). Within the EU and across all of Europe, differences in the nature and quality of OMFS training coexist. By implementing the highest possible standards of training, patient care can be improved.

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Introduction: The aim of this study was to evaluate whether a forensic odontologist working remotely could accurately undertake forensic dental identifications using videos produced by non-dental forensic staff operating an intra-oral video camera (IOVC). The study's aims were to assess the accuracy and time taken to perform remote forensic dental identifications in this manner.

Materials And Methods: Eight cadavers from the Centre for Anatomy and Human Identification (CAHID), University of Dundee, UK, were examined by a forensic odontologist via a traditional dental examination.

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Smoking and alcohol by HPV status in head and neck cancer: a Mendelian randomization study.

Nat Commun

September 2024

Department of Biostatistics, Princess Margaret Cancer Centre-University Health Network, University of Toronto, Toronto, Ontario, Canada.

HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are recognized as distinct entities. There remains uncertainty surrounding the causal effects of smoking and alcohol on the development of these two cancer types. Here we perform multivariable Mendelian randomization (MR) to evaluate the causal effects of smoking and alcohol on the risk of HPV-positive and HPV-negative HNSCC in 3431 cases and 3469 controls.

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Background: Traumatic brain injury is conventionally categorised as mild, moderate, or severe on the Glasgow Coma Scale (GCS). Recently developed biomarkers can provide more objective and nuanced measures of the extent of brain injury.

Methods: Exposure-response relationships were investigated in 2479 patients aged ≥16 enrolled in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) prospective observational cohort study.

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