Diabetes Educ
August 2014
The Center for Excellence in Primary Care, Department of Family and Community Medicine, University of California, San Francisco, California (Ms Ghorob, Dr Bodenheimer)
Purpose: The purpose of the study was to explore the perspectives and roles of peer coaches, who are patients with diabetes trained to provide diabetes self-management support (DSMS) to other patients.
Methods: A focus group and 17 qualitative semi-structured interviews were conducted with community-based peer coaches in San Francisco in order to better understand the process by which these coaches engaged with their patients. Transcripts were coded and analyzed using methods based on grounded theory to develop a theoretical model of peer coach roles.
Science
August 2010
Energy Biosciences Institute, the University of California Berkeley, Berkeley, CA 94720, USA.
In 2008, the world produced approximately 87 gigaliters of liquid biofuels, which is roughly equal to the volume of liquid fuel consumed by Germany that year. Essentially, all of this biofuel was produced from crops developed for food production, raising concerns about the net energy and greenhouse gas effects and potential competition between use of land for production of fuels, food, animal feed, fiber, and ecosystem services. The pending implementation of improved technologies to more effectively convert the nonedible parts of plants (lignocellulose) to liquid fuels opens diverse options to use biofuel feedstocks that reach beyond current crops and the land currently used for food and feed.
View Article and Find Full Text PDFGenes Immun
September 2007
Department of Molecular and Cell Biology, The University of California Berkeley, Berkeley, CA 94720-3202, USA.
The pathogenic fungus Histoplasma capsulatum causes disease ranging from mild to fatal in healthy and immunocompromised humans. Infection rates reach 80% in endemic areas, including the Midwestern United States. We used inbred mice to identify a 300-fold difference in fungal burden.
View Article and Find Full Text PDFSoc Sci Med
September 2007
The University of California--Berkeley/San Francisco, Center for Health and Community, 3333 California Street, Suite 465, Campus Box 0844, San Francisco, CA 94118, USA.
This study examines gender differences in the association between symptoms of depression and substance use during the transition from adolescence to young adulthood. Data are from three waves of the US-based National Longitudinal Study of Adolescent Health (n=10,828). Results from latent growth curve analysis demonstrate that the association between depressive symptomatology and substance use is bi-directional.
View Article and Find Full Text PDFCurr Opin Microbiol
December 2006
The Plant and Microbial Biology Department, The University of California Berkeley, CA 94720-3102, USA.
Non-self recognition resulting in programmed cell death is a ubiquitous phenomenon in filamentous ascomycete fungi and is termed heterokaryon incompatibility (HI). Recent analyses show that genes containing predicted HET domains are often involved in HI; however, the function of the HET domain is unknown. Autophagy is induced as a consequence of HI, whereas the presence of a predicted transcription factor, VIB-1, is required for HI.
View Article and Find Full Text PDFBiotechnol Bioeng
July 2004
Department of Chemical Engineering, The University of California Berkeley, California 94720-1462, USA.
Mono- and diterpenoids are of great industrial and medical value as specialty chemicals and pharmaceuticals. Production of these compounds in microbial hosts, such as Escherichia coli, can be limited by intracellular levels of the polyprenyl diphosphate precursors, geranyl diphosphate (GPP), and geranylgeranyl diphosphate (GGPP). To alleviate this limitation, we constructed synthetic operons that express three key enzymes for biosynthesis of these precursors: (1).
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