58 results match your criteria: "The University of Auckland Faculty of Medical and Health Sciences.[Affiliation]"

Background: Falls among older people are a major cause of the global burden of disease. This study investigated the implementation of the Falls and Fracture Prevention Programme, a multicomponent population-based intervention, across diverse districts in New Zealand.

Methods: We conducted a comparative case study through 28 semi-structured interviews with programme coordinators and managers across four districts.

View Article and Find Full Text PDF
Article Synopsis
  • Medical education publishing faces representation gaps due to epistemic injustice, which undermines the voices of certain groups in knowledge creation.
  • A diversity, equity, and inclusion working group has redefined rigor in peer review, aiming for a more equitable research system.
  • The journal's changes led to positive feedback on the peer review process and an increase in submissions from marginalized authors, highlighting the importance of allowing these authors to shape their narratives in knowledge production.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates whether ultrasound detection of monosodium urate crystals can predict the development of symptomatic gout in individuals with elevated urate levels over a five-year period.
  • It involves more than 250 participants with asymptomatic hyperuricemia, assessing various health metrics and using ultrasound imaging to monitor the presence of MSU crystal deposition.
  • The research is ethically approved and aims to share findings through peer-reviewed publications and conferences.
View Article and Find Full Text PDF

Prospective long-term follow-up after grommet insertion: Hearing and functional health outcomes in children.

Int J Pediatr Otorhinolaryngol

November 2024

Health NZ/Te Whatu Ora, Counties Manukau, ORL and Audiology Department, Auckland, New Zealand.

Objectives: To assess hearing levels and functional health outcomes of children two years after routine grommet surgery with standard care follow-up (discharge to General Practitioner (GP) care or Ear Nose and Throat (ENT) clinic appointment at 4-8 weeks).

Methods: Prospective cohort study of 89 children (average age of 7.98 years) recalled for audiological assessment 2 years after grommet surgery in a large ENT outpatient service in South Auckland, New Zealand.

View Article and Find Full Text PDF

Objectives: To evaluate the impact of persistent opioid use (POU) following surgery or trauma on health outcomes using linked data.

Summary Background Data: Surgery and trauma can lead to POU, characterised by continuous opioid consumption following hospital discharge. Outside the US, there is a lack of population-based studies on POU outcomes in opioid-naïve patients following these events.

View Article and Find Full Text PDF

Introduction: Asthma attacks are a leading cause of morbidity and mortality but are preventable in most if detected and treated promptly. However, the changes that occur physiologically and behaviourally in the days and weeks preceding an attack are not always recognised, highlighting a potential role for technology. The aim of this study 'DIGIPREDICT' is to identify early digital markers of asthma attacks using sensors embedded in smart devices including watches and inhalers, and leverage health and environmental datasets and artificial intelligence, to develop a risk prediction model to provide an early, personalised warning of asthma attacks.

View Article and Find Full Text PDF

Background: Māori (the Indigenous people of Aotearoa New Zealand (NZ)) are more likely to experience injury than non-Māori, but less likely to have effective access to publicly funded injury care services. It is unknown if this pattern extends into older age. This retrospective study analysed Accident Compensation Corporation (ACC; national no-fault injury compensation scheme) claims data to investigate ethnic variation in unintentional injury claims and related costs for older adults (≥50 years).

View Article and Find Full Text PDF

Objective: The purpose of this study was to explore the experiences of Māori patients and their families accessing care for an acute out-of-hospital cardiac event and to identify any barriers or enablers of timely access to care.

Design: Eleven interviews with patients and their families were conducted either face-to-face or using online conferencing. Interviews were audio-recorded and transcribed for thematic analysis using Kaupapa Māori methodology.

View Article and Find Full Text PDF

Background: Persistent opioid use (POU) is common after surgery and is associated with an increased risk of mortality and morbidity. There have been no population-based studies exploring POU in opioid-naïve surgical patients in New Zealand (NZ). This study aimed to determine the incidence and risk factors for POU in opioid-naïve patients undergoing surgery in all NZ hospitals.

View Article and Find Full Text PDF

Introduction: The COVID-19 pandemic has had both direct and indirect impacts on the health of populations worldwide. While racial/ethnic health inequities in COVID-19 infection are now well known (and ongoing), knowledge about the impact of COVID-19 pandemic management on non-COVID-19-related outcomes for Indigenous peoples is less well understood. This article presents the study protocol for the Health Research Council of New Zealand funded project 'Mā te Mōhio ka Mārama: Impact of COVID-19 on Māori:non-Māori inequities'.

View Article and Find Full Text PDF

Objective: To investigate the effect of different doses of prophylactic dextrose gel on neurocognitive function and health at 6-7 years.

Design: Early school-age follow-up of the pre-hPOD (hypoglycaemia Prevention with Oral Dextrose) study.

Setting: Schools and communities.

View Article and Find Full Text PDF

A validation of placental pathology reports by ethnicity in New Zealand, through systematic analysis of histological slides.

Placenta

January 2024

Auckland District Health Board LabPlus, Auckland City Hospital, Building 31, Gate 4 Grafton Road, Grafton, Auckland, 1148, New Zealand. Electronic address:

Introduction: Reliability studies of placental examination have shown differing interobserver agreement for certain pathological features, a lack of uniform reporting criteria and variable experience among pathologists. In previous analyses we have shown that placental pathology differs by ethnicity. This validation study was performed to investigate whether bias related to ethnicity is a feature of placental pathology reporting in New Zealand (NZ).

View Article and Find Full Text PDF

Multinodal Cervical Angiomyomatous Hamartoma.

Int J Surg Pathol

September 2024

Department of Pathology, Auckland City Hospital, Auckland, New Zealand.

Angiomyomatous hamartoma (AMH) is a rare benign lesion of the lymph nodes. Angiomyomatous hamartoma tends to be found in inguinal lymph nodes, and usually in a single lymph node. We present a rare care case of a 53-year-old presenting with a neck lump, found to be AMH involving multiple lymph nodes in her neck.

View Article and Find Full Text PDF

Background: Health information technology (HIT) is increasingly used to enable health service/system transformation. Most HIT implementations fail to some degree; very few demonstrate sustainable success. No guidelines exist for health service leaders to leverage factors associated with success.

View Article and Find Full Text PDF

Although tuberous sclerosis (TS) may affect many organs, vascular manifestations involving medium- and large-size vessels are rare. We present a young child with known TS who presented with bilateral posterior circulation infarcts and subsequently was found to have right-hand ischaemia secondary to a thrombosed brachial artery aneurysm. A wound on his right middle finger failed to heal with conservative management, and digital subtraction angiography and MR angiogram demonstrated a lack of bypass target with microcollateral supply of the forearm only.

View Article and Find Full Text PDF

Pontine ischaemic stroke syndromes.

Pract Neurol

November 2023

Department of Neurology, Wellington Regional Hospital, Newtown, New Zealand.

Classic Raymond syndrome is a rare neurological presentation comprising ipsilateral abducens palsy, contralateral facial paresis and contralateral hemiparesis. We present a man in his late 60s who presented with diplopia, dysarthria and right-sided limb weakness. This syndrome is one of a group of 'crossed paralyses' of the caudal pons.

View Article and Find Full Text PDF

Background: International and national New Zealand (NZ) research has identified women of South Asian ethnicity at increased risk of perinatal mortality, in particular stillbirth, with calls for increased perinatal research among this ethnic group. We aimed to analyse differences in pregnancy outcomes and associated risk factors between South Asian, Māori, Pacific and NZ European women in Aotearoa NZ, with a focus on women of South Asian ethnicity, to ultimately understand the distinctive pathways leading to adverse events.

Methods: Clinical data from perinatal deaths between 2008 and 2017 were provided by the NZ Perinatal and Maternal Mortality Review Committee, while national maternity and neonatal data, and singleton birth records from the same decade, were linked using the Statistics NZ Integrated Data Infrastructure for all births.

View Article and Find Full Text PDF
Article Synopsis
  • Sporadic Alzheimer's disease (sAD) is characterized by selective neurodegeneration in specific brain regions, which the authors suggest is influenced by local disruptions in ApoER2-Dab1 signaling rather than the traditional prion-like Tau spread model.
  • The study used various methods to investigate the expression of ApoER2 and components of the RAAAD-P-LTP pathway in neurons, particularly in areas affected by early Tau pathology.
  • Findings indicate that neurons vulnerable to degeneration express high levels of ApoER2 and show accumulation of RAAAD-P-LTP components, which are linked to cognitive deficits and the progression of sAD.
View Article and Find Full Text PDF

The benefits of palliative care programs are well documented. However, the effectiveness of specialist palliative care services is not well established. The previous lack of consensus on criteria for defining and characterizing models of care has restrained direct comparison between these models and limited the evidence base to inform policy makers.

View Article and Find Full Text PDF

Objectives: To describe the incidence of and patterns of 'escalated care' (care in addition to standard treatment with systemic corticosteroids and inhaled bronchodilators) for children receiving prehospital treatment for asthma.

Design: Retrospective observational study.

Setting: State-wide ambulance service data (Ambulance Victoria in Victoria, Australia, population 6.

View Article and Find Full Text PDF

Introduction: New Zealand (NZ) has high rates of pediatric acute hematogenous osteomyelitis (AHO) with males and children of Pasifika and Māori ethnicity overrepresented.

Aims: To update the incidence of Pediatric AHO over 10 years, identifying trends in presentation, organisms, treatment, and outcomes.

Methods: A 10-year retrospective review of children aged 6 weeks to 15 years admitted with Pediatric AHO across two centers from 2008 to 2017.

View Article and Find Full Text PDF

Introduction: Women of South Asian ethnicity are overrepresented in adverse pregnancy outcome across high-income countries, including those related to placental dysfunction. It has been hypothesised that placental aging occurs at earlier gestation in South Asian pregnancies. We aimed to identify differences in placental pathology among perinatal deaths ≥28 weeks gestation, between South Asian, Māori and New Zealand (NZ) European women in Aotearoa NZ, with a focus on women of South Asian ethnicity.

View Article and Find Full Text PDF

Background: Despite numerous echocardiographic screening studies of children in high incidence acute rheumatic fever (ARF)/rheumatic heart disease (RHD) communities, little is known about the prevalence of RHD in adults in these populations.We sought to determine the prevalence of RHD in an urban area of South Auckland, New Zealand, where previous studies had shown the prevalence of RHD in children to be around 2%.

Methods: A cross-sectional screening study was conducted between 2014 and 2016.

View Article and Find Full Text PDF

Placental pathology findings amongst extremely preterm perinatal deaths in Aotearoa New Zealand.

Placenta

June 2023

The University of Auckland Faculty of Medical and Health Sciences, Obstetrics & Gynaecology, Auckland, New Zealand Building 507, 22-30 Park Avenue, Grafton, Auckland, 1023, New Zealand. Electronic address:

Introduction: Women of South Asian ethnicity are overrepresented in adverse pregnancy outcomes across high-income countries, including placental dysfunction and antepartum haemorrhage. As the burden of mortality is highest for extremely preterm infants, we aimed to identify any differences in placental pathology among perinatal deaths from 20 to 27 weeks gestation between South Asian, Māori and New Zealand (NZ) European women in Aotearoa NZ, with a focus on women of South Asian ethnicity.

Methods: Placental pathology reports and clinical data from perinatal deaths between 2008 and 2017 were provided by the NZ Perinatal and Maternal Mortality Review Committee, blinded and analysed by an experienced perinatal pathologist using the Amsterdam Placental Workshop Group Consensus Statement criteria.

View Article and Find Full Text PDF