HPV32-related Heck's disease in a chronic graft-versus-host disease patient with long-term successful KTP laser treatment: A rare case report.

We recently identified and treated a rare case of oral focal epithelial hyperplasia (FEH) in an adult patient with chronic graft-vs-host disease. This is the first report linking KTP laser therapy to successful long-term treatment HPV32 FEH.

Zinc allocation to and within seeds: Different strategies of metal homeostasis in accessions under divergent selection pressure.

Vegetative tissues of metal(loid)-hyperaccumulating plants are widely used to study plant metal homeostasis and adaptation to metalliferous soils, but little is known about these mechanisms in their seeds. We explored essential element allocation to seeds, a species that faces a particular trade-off between meeting nutrient requirements and minimizing toxicity risks.Combining advanced elemental mapping (micro-particle induced X-ray emission) with chemical analyses of plant and soil material, we investigated natural variation in Zn allocation to seeds from non-metalliferous and metalliferous locations.

Empowering Clinician Education With Patient-outcome Feedback.

Emergency physicians (EPs) often lack the information they need about their patients' outcomes so that they can both optimally adjust and refine their diagnostic and treatment processes and recognize their clinical errors. Patient-outcome feedback (POF) provides that information by informing clinicians about a patient's clinical course after that clinician's evaluation and treatment. This feedback may encompass the period after the EP has transferred a patient's care to another EP or after the patient has left the ED or hospital.

Correction to: Cluster identification, selection, and description in Cluster randomized crossover trials: the PREP-IT trials.

An amendment to this paper has been published and can be accessed via the original article.

Cluster identification, selection, and description in cluster randomized crossover trials: the PREP-IT trials.

Background: In cluster randomized crossover (CRXO) trials, groups of participants (i.e., clusters) are randomly allocated to receive a sequence of interventions over time (i.

Evaluation of Gender Differences in Ultrasound Milestone Evaluations During Emergency Medicine Residency Training: A Multicenter Study.

Objectives: Prior literature has demonstrated incongruities among faculty evaluation of male and female residents' procedural competency during residency training. There are no known studies investigating gender differences in the assessment of procedural skills among emergency medicine (EM) residents, such as those required by ultrasound. The objective of this study was to determine if there are significant gender differences in ultrasound milestone evaluations during EM residency training.

Robust Remote Sensing of Trace-Level Heavy-Metal Contaminants in Water Using Laser Filaments.

Water is the major natural resource that enables life on our planet. Rapid detection of water pollution that occurs due to both human activity and natural cataclysms is imperative for environmental protection. Analytical chemistry-based techniques are generally not suitable for rapid monitoring because they involve collection of water samples and analysis in a laboratory.

Integrating herbarium specimen observations into global phenology data systems.

Premise Of The Study: The Plant Phenology Ontology (PPO) was originally developed to integrate phenology observations of whole plants across different global observation networks. Here we describe a new release of the PPO and associated data pipelines that supports integration of phenology observations from herbarium specimens, which provide historical and modern phenology data.

Methods And Results: Critical changes to the PPO include key terms that describe how measurements from parts of plants, which are captured in most imaged herbarium specimens, relate to whole plants.

Imaging of Pelvic and Femoral Fixation Hardware: Normal Findings and Hardware Failure.

Good outcomes following treatment of pelvic ring injuries, acetabular fractures, and femur fractures rely on restoration of native pelvic or limb alignment, anatomical reduction and rigid stability of articular fractures, and early postoperative mobilization. Multiple surgical approaches, reduction aids, and orthopaedic implants are available to stabilize these fractures. Despite best practices, complications including hardware failure, nonunions, malunions, and infections occur.

Talking About Professionalism Through the Lens of Professional Identity.

Professionalism is one of the Accreditation Council for Graduate Medical Education's (ACGME) Core Competencies, but the breadth of its content often makes this a difficult topic, both in remedial counseling and when presenting the topic to medical trainees and practicing clinicians. Physician professionalism encompasses both clinical competence and the virtues that comprise the physician's social contract. This difficult subject may best be approached tangentially, through the lens of professional identity.

Nursing Unit Communication During a US Public Health Emergency: Natural Experiment.

Background: In the second half of 2014, the first case of Ebola virus disease (EVD) was diagnosed in the United States. During this time period, we were collecting data for the Measuring Network Stability and Fit (NetFIT) longitudinal study, which used social network analysis (SNA) to study relationships between nursing staff communication patterns and patient outcomes. One of the data collection sites was a few blocks away from where the initial EVD diagnosis was made.

Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region.

The up-regulated expression of E-type prostanoid (EP) 4 receptors has been implicated in carcinogenesis; however, the expression of EP4 receptors has also been reported to be weaker in tumor tissues than in normal tissues. Indeed, EP4 receptors have been suggested to play a role in the maintenance of colorectal homeostasis. This study aimed to examine the underlying mechanisms/reasons for why inconsistent findings have been reported regarding EP4 receptor expression levels in homeostasis and carcinogenesis by focusing on cellular densities.

Grazing effect on grasslands escalated by abnormal precipitations in Inner Mongolia.

Grazing effects on arid and semi-arid grasslands can be constrained by aridity. Plant functional groups (PFGs) are the most basic component of community structure (CS) and biodiversity & ecosystem function (BEF). They have been suggested as identity-dependent in quantifying the response to grazing intensity and drought severity.

Mesoporous TiO-SiO adsorbent for ultra-deep desulfurization of organic-S at room temperature and atmospheric pressure.

Ultra-deep desulfurization is a major requirement for upgrading the quality of fuel and power sources for fuel-cells. A series of mesoporous TiO-SiO adsorbents were prepared and investigated for ultra-deep adsorption of benzothiophene (BT) and dibenzothiophene (DBT) from model fuel at ambient conditions. The adsorbents were characterized SEM, XRD, N-BET, FT-IR and NH-TPD techniques.

Use of Social Media in Emergency Ultrasound Fellowship Programs.

Objective: Social media has been gaining traction among learners and educators for its ability to stimulate discussion, increase participation, and promote knowledge sharing. Despite the growing research around the benefits of social media in education, there is little evidence on how it is being incorporated into emergency ultrasound (EUS) fellowships. This study aims to determine the preference and use of social media by engaging with program directors across EUS programs in the United States to assess the current landscape of and attitudes toward social media use.

Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists.

The misuse of prescription opiates is on the rise with combination therapies (e.g. acetaminophen or NSAIDs) resulting in severe liver and kidney damage.

Calcium-Sensing Receptor Regulates Cytosolic [Ca ] and Plays a Major Role in the Development of Pulmonary Hypertension.

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary vascular resistance (PVR) leading to right heart failure and premature death. The increased PVR results in part from pulmonary vascular remodeling and sustained pulmonary vasoconstriction. Excessive pulmonary vascular remodeling stems from increased pulmonary arterial smooth muscle cell (PASMC) proliferation and decreased PASMC apoptosis.

Analyzing Patterns of Community Interest at a Legacy Mining Waste Site to Assess and Inform Environmental Health Literacy Efforts.

Understanding a community's concerns and informational needs is crucial to conducting and improving environmental health research and literacy initiatives. We hypothesized that analysis of community inquiries over time at a legacy mining site would be an effective method for assessing environmental health literacy efforts and determining whether community concerns were thoroughly addressed. Through a qualitative analysis, we determined community concerns at the time of being listed as a Superfund site.

Impact of Donor Arterial Partial Pressure of Oxygen on Outcomes After Lung Transplantation in Adult Cystic Fibrosis Recipients.

Introduction: Donor PaO2 levels are used for assessing organs for lung transplantation (LTx), but survival implications of PaO2 levels in adult cystic fibrosis (CF) patients receiving LTx are unclear.

Methods: UNOS registry data spanning 2005-2013 were used to test for associations of donor PaO2 with patient survival and bronchiolitis obliterans syndrome (BOS) in adult (age ≥ 18 years) first-time LTx recipients diagnosed with CF.

Results: The analysis included 1587 patients, of whom 1420 had complete data for multivariable Cox models.

Whither the "Improvement Standard"? Coverage for Severe Brain Injury after Jimmo v. Sebelius.

As improvements in neuroscience have enabled a better understanding of disorders of consciousness as well as methods to treat them, a hurdle that has become all too prevalent is the denial of coverage for treatment and rehabilitation services. In 2011, a settlement emerged from a Vermont District Court case, Jimmo v. Sebelius, which was brought to stop the use of an "improvement standard" that required tangible progress over an identifiable period of time for Medicare coverage of services.