15 results match your criteria: "The University of Adelaide and Robinson Research Institute[Affiliation]"
Front Endocrinol (Lausanne)
May 2024
Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Polycystic Ovary Syndrome (PCOS) presents multifaceted challenges affecting women's reproductive, metabolic, and psychological systems, consequently impacting their psychological and emotional well-being. The utilization of meditation and mindfulness interventions (MMIs) is found to be increasing for the management of PCOS. This scoping review systematically explored the current literature to identify the type and application of MMIs for PCOS management.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
September 2024
Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria 3168, Australia.
J Clin Endocrinol Metab
May 2024
NICM Health Research Institute, Western Sydney University, Penrith 2751, Australia.
Clin Endocrinol (Oxf)
February 2024
Monash Centre for Health Research and Implementation, Clinical and Molecular Medicine, Monash University, Melbourne, Victoria, Australia.
Objective: Characteristic features of polycystic ovary syndrome (PCOS) include insulin resistance and an increased risk for type 2 diabetes. To promote improved insulin sensitivity, insulin sensitisers have been used in PCOS. However, direct comparisons across these agents are limited.
View Article and Find Full Text PDFEClinicalMedicine
September 2023
Monash Centre for Health Research and Implementation (MCHRI), Monash University, Clayton, VIC, Australia.
Background: Anti-androgens and combined oral contraceptive pills (COCPs) may mitigate hyperandrogenism-related symptoms of polycystic ovary syndrome (PCOS). However, their efficacy and safety in PCOS remain unclear as previous reviews have focused on non-PCOS populations. To inform the 2023 International Evidence-based Guideline in PCOS, we conducted the first systematic review and meta-analysis investigating the efficacy and safety of anti-androgens in the management of hormonal and clinical features of PCOS.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2024
Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria 3168, Australia.
Context: Polycystic ovary syndrome (PCOS) affects more than 1 in 10 women.
Objective: As part of the 2023 International PCOS Guidelines update, comparisons between combined oral contraceptive pills (COCP), metformin, and combination treatment were evaluated.
Data Sources: Ovid Medline, Embase, PsycINFO, All EBM, and CINAHL were searched.
Eur J Endocrinol
August 2023
Monash Centre for Health Research and Implementation, School of public Health and Preventive Medicine, Monash University, Clayton, VIC 3168, Australia.
Eur J Endocrinol
July 2023
Monash Centre for Health Research & Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, VIC 3800, Australia.
Objective: To compare between different combined oral contraceptive pills (COCPs) as part of the update of the International Evidence-Based Guidelines on the Assessment and Management of polycystic ovary syndrome (PCOS).
Design: A systematic review and meta-analysis was performed, Prospero CRD42022345640.
Methods: MEDLINE, EMBASE, All EBM, CINAHL, and PsycINFO was searched on July, 8, 2022, for studies including women with PCOS, comparing 2 different COCPs in randomized controlled trials.
Clin Endocrinol (Oxf)
July 2023
Monash Centre for Health Research & Implementation, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victori, Australia.
Objective: As part of the update of the International Evidence-Based Guidelines for the Assessment and Management of polycystic ovary syndrome (PCOS), a systematic review was performed to inform evidence-based recommendations.
Design: Systematic review. Only randomised controlled trial were included.
Int J Oral Maxillofac Surg
January 2023
Department of Periodontology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Jinan, Shandong, China. Electronic address:
This systematic review and meta-analysis was performed to compare the clinical effect of surgical treatment of peri-implantitis alone or in combination with graft material. Literature searches were conducted up to June 20, 2020. Randomized controlled trials (RCTs) comparing the clinical effects of open flap debridement (OFD) alone and OFD with adjunctive graft materials for the treatment of peri-implantitis were included.
View Article and Find Full Text PDFClin Endocrinol (Oxf)
October 2019
Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia.
Background: Polycystic ovary syndrome (PCOS) has a prevalence of 8%-13%. Given the prevalence, diverse health impacts and variation in care, rigorous evidence-based guidelines are needed in PCOS management. This systematic review with meta-analyses aimed to investigate the effect of the combined oral contraceptive pill (COCP) and/or metformin in the management of hormonal and clinical features of PCOS, to inform international guidelines.
View Article and Find Full Text PDFGenes Brain Behav
June 2019
Department of Molecular and Cellular Biology, The University of Adelaide and Robinson Research Institute, Adelaide, South Australia, Australia.
Mutations in proline-rich transmembrane protein 2 (PRRT2) cause a range of episodic disorders that include paroxysmal kinesigenic dyskinesia and benign familial infantile epilepsy. Mutations are generally loss of function and include the c649dupC frameshifting mutation that is present in around 80% of affected individuals. To investigate how Prrt2 loss of function mutations causes disease, we performed a phenotypic investigation of a transgenic Prrt2 knockout (Prrt2 KO) mouse.
View Article and Find Full Text PDFPediatr Diabetes
December 2018
Discipline of Paediatrics, The University of Adelaide and Robinson Research Institute, North Adelaide, South Australia, Australia.
Background/objective: Adolescents with type 1 diabetes have early macrovascular changes (increased intima-media thickness [IMT]) and early retinal changes that predict clinical disease in adulthood. We hypothesized that early changes in the macrovascular and retinal microvascular beds develop in parallel before retinopathy develops. We therefore aimed to investigate the relationship between changes in atherosclerosis (carotid and aortic IMT) and retinal vascular geometry cross-sectionally and longitudinally in adolescents with type 1 diabetes.
View Article and Find Full Text PDFHorm Res Paediatr
October 2018
Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania, USA.
This paper represents an international collaboration of paediatric endocrine and other societies (listed in the Appendix) under the International Consortium of Paediatric Endocrinology (ICPE) aiming to improve worldwide care of adolescent girls with polycystic ovary syndrome (PCOS)1. The manuscript examines pathophysiology and guidelines for the diagnosis and management of PCOS during adolescence. The complex pathophysiology of PCOS involves the interaction of genetic and epigenetic changes, primary ovarian abnormalities, neuroendocrine alterations, and endocrine and metabolic modifiers such as anti-Müllerian hormone, hyperinsulinemia, insulin resistance, adiposity, and adiponectin levels.
View Article and Find Full Text PDFPediatr Diabetes
February 2018
Discipline of Paediatrics, The University of Adelaide and Robinson Research Institute, North Adelaide, SA, Australia.
Background And Objective: Children with type 1 diabetes (T1D) have vascular dysfunction and frequently struggle to adhere to dietary recommendations. Limited data exist for the vascular consequences of poor diet quality in children. We aimed to evaluate the association between dietary components and vascular function in children with T1D.
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