The Link between Gene RS4977574 Polymorphism and Common Atherosclerosis Cardiovascular Complications: A Hospital-Based Case-Control Study in Ukrainian Population.

Materials And Methods: 195 patients with ACS, 200 patients with LAS, and 234 control subjects were enrolled in this case-control study. Real-time PCR was used for rs4977574 genotyping. SPSS software package (version 17.

The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene () and Arterial Hypertension Development in Ukrainian Population.

Arterial hypertension (AH) belongs to the diseases with genetic predisposition that determines the necessity of research on the genetic component's influence on this disease development. It is suggested that one of the salt-sensitive arterial hypertension potential markers may be the alpha-adducin gene because its protein product is involved in the ion transport regulation in the renal epithelium. Thus, the aim of the study was to investigate the association between Gly460Trp-polymorphism and the AH development risk among patients with different risk factors in the Ukrainian population.

[The initial period of functioning of the Medical Faculty of the Imperial University of the Saint Vladimir and teaching of medical police].

The article considers the circumstances of the beginning of teaching medical police at St.Vladimir Imperial University in Kiev that was investigated for the first time. It was established that the medical police were taught as one of academic disciplines at the Department of State Medicine Studies.

Association Study between Gene III Polymorphism and Type 2 Diabetes Mellitus Development in Ukrainian Population.

Type 2 diabetes mellitus (T2DM) belongs to the diseases with hereditary predisposition, so both environmental and genetic factors contribute to its development. Recent studies have demonstrated that the skeleton realizes systemic regulation of energy metabolism through the secretion of osteocalcin (OCN). Thus, the association analysis between III single nucleotide polymorphism of OCN gene () promoter region and T2DM development in Ukrainian population was carried out.

[I. A. Petrovsky and Implementation of Qualitative Approach into Clinical Medicine].

The article covers the life and the work of Ivan A. Petrovsky, doctor of medicine. His contribution into propaganda in the Russian Empire of the idea of French physician Pierre-Charles-Alexandre Louis (1787-1872) concerning necessity of applying the statistical method in the clinical medicine.