Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis.

Background: The advancement of nanotechnology underscores the imperative need for establishing in silico predictive models to assess safety, particularly in the context of chronic respiratory afflictions such as lung fibrosis, a pathogenic transformation that is irreversible. While the compilation of predictive descriptors is pivotal for in silico model development, key features specifically tailored for predicting lung fibrosis remain elusive. This study aimed to uncover the essential predictive descriptors governing nanoparticle-induced pulmonary fibrosis.

Formation Regularities of Plasmonic Silver Nanostructures on Porous Silicon for Effective Surface-Enhanced Raman Scattering.

Plasmonic nanostructures demonstrating an activity in the surface-enhanced Raman scattering (SERS) spectroscopy have been fabricated by an immersion deposition of silver nanoparticles from silver salt solution on mesoporous silicon (meso-PS). The SERS signal intensity has been found to follow the periodical repacking of the silver nanoparticles, which grow according to the Volmer-Weber mechanism. The ratio of silver salt concentration and immersion time substantially manages the SERS intensity.

Fraunhofer diffraction by a random screen.

The stochastic approach is applied to the problem of Fraunhofer diffraction by a random screen. The diffraction pattern is expressed through the random chord distribution. Two cases are considered: the sparse ensemble, where the interference between different obstacles can be neglected, and the densely packed ensemble, where this interference is to be taken into account.

Oxygen quenching of excited singlet and triplet states of polycyclic aromatic hydrocarbons in the vapor phase.

The quenching rate constants of excited singlet (k(S)(O2)) and triplet (k(T)(O2)) states by oxygen were investigated in the vapor phase for polycyclic aromatic hydrocarbons having distinguishing oxidation potentials E(ox). The significant spread in the rate constants was found (4x10(5)s(-1)Torr(-1) View Article and Find Full Text PDF