89 results match your criteria: "The Steadman Philippon Research Institute.[Affiliation]"

Background: Subscapularis tendon (SSc) dysfunction after total shoulder arthroplasty (TSA) results in poor functional outcomes. There have been numerous SSc repair constructs tested biomechanically and clinically; however, none has been demonstrated as superior. Newer techniques and implants have emerged but have not been fully tested.

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Background: To report clinical and activity-specific outcomes after arthroscopic rotator cuff repair (ARCR) for full-thickness supraspinatus tears in active individuals aged less than or equal to 45 years. The pre hoc hypothesis was that patients in this age group would demonstrate significant improvements in clinical outcomes following ARCR along with a significant improvement of athletic abilities.

Methods: Patients were included in this study if they were (1) active individuals aged between 18 and 45 years at the time of surgery, (2) had a full-thickness rotator cuff tear of the supraspinatus tendon with or without anterior or posterior extension, and (3) underwent ARCR.

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Article Synopsis
  • Heart failure due to heat stress is a significant concern for aquatic ectotherms, and mitochondrial dysfunction may play a key role in this issue.
  • The study focused on the thermal sensitivity of cardiac mitochondria in three-spined stickleback fish, examining factors like temperature, fatty acid composition, and age.
  • Results showed that while temperature strongly affected mitochondrial respiration, fish age also influenced it, revealing higher EPA levels in older fish but no direct correlation with critical thermal maximum (CTmax).
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Article Synopsis
  • A study looked at how much patients improved after surgery for snapping scapula syndrome over two years.
  • Researchers wanted to find out what factors helped patients feel satisfied with their results and to see if certain conditions led to better improvements.
  • They found that patients showed significant improvements in their health scores and pain levels after the surgery, which means the treatment worked pretty well.
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Background: In the Latarjet procedure, the ideal placement of the coracoid graft in the medial-lateral position is flush with the anterior glenoid rim. However, the ideal position of the graft in the superior-inferior position (sagittal plane) for restoring glenohumeral joint stability is still controversial.

Purpose: To compare coracoid graft clockface positions between the traditional 3 to 5 o'clock and a more inferior (for the right shoulder) 4 to 6 o'clock with regard to glenohumeral joint stability in the Latarjet procedure.

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Mesenchymal stromal cell response to intervertebral disc-like pH is tissue source dependent.

J Orthop Res

June 2024

Laboratory of Orthopaedic Tissue Regeneration and Orthobiologics, Department of Bioengineering, Clemson University, Clemson, South Carolina, USA.

Intervertebral disc (IVD) degeneration (IVDD) has become increasingly prevalent and is a common contributing factor to low back pain. Current treatment options are limited to either symptom management or surgery. A promising treatment option being explored is intradiscal administration of mesenchymal stromal cells (MSCs).

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Purpose: This study aimed to analyze the risk of reoperation following autologous chondrocyte implantation (ACI) of the knee utilizing third-generation ACI products in a time-to-event analysis and report on the associated patient-reported outcome measures (PROM) in case of reoperation.

Methods: Patients undergoing ACI were included from a longitudinal database. Patient age, sex, body mass index (BMI), number of previous surgeries, lesion localization, lesion size, symptom duration, as well as time and type of reoperation was extracted.

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Article Synopsis
  • Humeral head reconstruction using fresh osteochondral allografts (OCA) is being explored as a viable option for treating shoulder stability issues, particularly due to the matching properties of talus bone grafts with joint surfaces.* -
  • A controlled study using seven cadaver shoulders evaluated how talus OCA plugs affect the surface geometry of humeral heads with varying sizes of Hill-Sachs lesions (HSLs), showing significant improvements in surface area and congruency.* -
  • Results indicated that while the native shoulder surface area was significantly lower, OCA augmentation notably increased surface area and congruency across all sizes of HSLs, confirming the effectiveness of talus OCA in shoulder reconstruction.*
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Encapsulation of β-NGF in injectable microrods for localized delivery accelerates endochondral fracture repair.

Front Bioeng Biotechnol

May 2023

Graduate Program in Oral and Craniofacial Sciences, School of Dentistry, University of California, San Francisco (UCSF), San Francisco, CA, United States.

Currently, there are no non-surgical FDA-approved biological approaches to accelerate fracture repair. Injectable therapies designed to stimulate bone healing represent an exciting alternative to surgically implanted biologics, however, the translation of effective osteoinductive therapies remains challenging due to the need for safe and effective drug delivery. Hydrogel-based microparticle platforms may be a clinically relevant solution to create controlled and localized drug delivery to treat bone fractures.

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Purpose Of Review: Shoulder instability in patients with underlying joint hyperlaxity can be challenging to treat. Poorly defined terminology, heterogeneous treatments, and sparse reports on clinical outcomes impair the development of best practices in this patient population. This article provides a review of the current literature regarding optimal management of patients suffering from shoulder instability with concomitant hyperlaxity of the shoulder, from isolated shoulder joint hyperlaxity to congenital hypermobility spectrum disorders (HSD).

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Purpose: Anterior cruciate ligament tears and anterior cruciate ligament reconstruction (ACLR) are common in young athletes. The modifiable and non-modifiable factors contributing to ACLR failure and reoperation are incompletely understood. The purpose of this study was to determine ACLR failure rates in a physically high-demand population and identify the patient-specific risk factors, including prolonged time between diagnosis and surgical correction, that portend failure.

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Superior Capsular Reconstruction for Irreparable Rotator Cuff Tear.

Clin Sports Med

January 2023

The Steadman Philippon Research Institute, 181 W Meadow Drive, Suite 400, Vail, CO 81657, USA; The Steadman Clinic, 181 W Meadow Drive, Suite 400, Vail, CO 81657, USA. Electronic address:

Superior capsular reconstruction (SCR) was developed as a minimally invasive, innovate technique to restore normal shoulder biomechanics for patients who present with massive, irreparable rotator cuff tear (MIRCTs) that preclude shoulder arthroplasty. Current studies have shown that SCR for MIRCTs result in excellent short-term clinical outcomes, adequate pain relief, and functional improvement with low graft failure and complication rates. This article aims to critically evaluate the biomechanics, indications, procedural considerations, clinical outcomes, rehabilitation program, and complications associated with the SCR procedure.

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Article Synopsis
  • Anterior shoulder instability (ASI) can lead to a higher likelihood of developing osteoarthritis and needing shoulder replacement surgery, prompting this systematic review to analyze outcomes for such patients post-arthroplasty.
  • A thorough literature search across multiple medical databases included 16 studies with a total of 596 patients, focusing on various surgical techniques and follow-up care related to shoulder arthroplasty outcomes.
  • The review found no significant differences in recovery and outcomes between patients with a history of ASI and those without, indicating that shoulder arthroplasty can be effective for individuals with prior instability.
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Reverse Hill-Sachs lesions (rHSLs) after chronic posterior shoulder instability are important to recognize and treat appropriately. Treatment options for posterior instability with rHSL in the current literature are primarily based on percentage of humeral bone loss. In cases of moderate (25% to 50%) anterolateral humeral head bone loss, fresh osteochondral allografts are preferred.

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There is an unmet need for improved, clinically relevant methods to longitudinally quantify bone healing during fracture care. Here we develop a smart bone plate to wirelessly monitor healing utilizing electrical impedance spectroscopy (EIS) to provide real-time data on tissue composition within the fracture callus. To validate our technology, we created a 1-mm rabbit tibial defect and fixed the bone with a standard veterinary plate modified with a custom-designed housing that included two impedance sensors capable of wireless transmission.

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Background: Anterior and posterior glenoid bone loss morphology have both been individually and morphologically described in previous studies. While there exists substantial literature on anterior bone loss, and emerging evidence describing posterior bone loss, a direct comparison between the two is lacking in the current literature. The purpose of this study is to quantitatively compare the anatomic and morphological differences in glenoid bone loss (GBL) in operative patients with anterior versus posterior glenohumeral instability.

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Background: Full-thickness rotator cuff tears (FTRCTs) represent a common shoulder injury that, if untreated, can progress in size, become increasingly painful, and inhibit function. These lesions are often surgically repaired, with double-row arthroscopic repair often preferred for larger tears. Biological augmentation technologies have been developed to improve rates of postoperative radiographic retear and enhance patient-reported outcomes after surgical FTRCT repair.

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Fresh distal tibia allograft (DTA) has been gaining popularity among surgeons as an anatomic reconstruction option for the treatment of significant glenoid bone loss. Fresh DTA results in a clinically stable joint with excellent clinical outcomes and minimal graft resorption, and it has similar outcomes as the Latarjet procedure. Proper graft preparation and fixation are critical to ensuring optimal outcomes.

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Hypothesis/background: There is no consensus on whether to repair the subscapularis in the setting of reverse total shoulder arthroplasty (rTSA). There have been an assortment of studies showing mixed results regarding shoulder stability and postoperative strength outcomes when looking at subscapularis repair in rTSA. The purpose of this systematic review was to investigate differences in biomechanical strength outcomes of cadaveric subscapularis repair vs.

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Importance: Repair of the subscapularis can be effective in the setting of reverse total shoulder arthroplasty (rTSA). However, there has yet to be a consensus on an optimal repair technique.

Objectives: The purpose of this systematic review is to consolidate current high-quality studies comparing outcomes after rTSA with different subscapularis repair techniques.

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Sternoclavicular Joint Instability and Reconstruction.

J Am Acad Orthop Surg

August 2022

From the Steadman Philippon Research Institute, Vail, CO (Provencher, Bernholt, Peebles, and Millett), and The Steadman Clinic, Vail, CO (Provencher and Millett).

Chronic instability or degenerative arthritis of the sternoclavicular (SC) joint may occur after traumatic or spontaneous dislocation of the SC joint. Most commonly, chronic instability of the SC joint occurs anteriorly; however, posterior instability has an increased risk of serious complications because of proximity to mediastinal structures. Although chronic anterior instability of the SC joint does not resolve with nonsurgical treatment, patients often have mild symptoms that do not impair activities of daily living; however, chronic anterior SC joint instability may be functionally limiting in more active individuals.

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Traditionally, total shoulder arthroplasty is performed using a deltopectoral approach through which the glenohumeral joint is accessed by mobilization of the subscapularis. Despite several variations on the subscapularis management techniques, postoperative complications, including subscapularis deficiency and lower functional outcomes, remain an area for improvement. The purpose of this Technical Note is to describe in detail our technique for management of the subscapularis in the setting of a stemless humeral implant through which the repair is planned and almost entirely performed at the beginning of the case, prior to the subscapularis peel.

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Instability of the proximal tibiofibular joint (PTFJ) can be post-traumatic or due to accumulative injuries and may also be underdiagnosed pathology that can present with symptoms of lateral and/or medial knee pain. It can be associated with subtle instability and subluxation or frank dislocation of both the PTFJ and the native knee joint. Previously described techniques have been either nonanatomic, require secondary hardware removal, disrupt native anatomy, or fail to account for the inherent stabilizing effect of the lateral collateral ligament, which is likely additionally injured or lax in these patients.

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Background: Three-dimensional (3D) preoperative planning software for reverse total shoulder arthroplasty (rTSA) has been implemented in recent years in order to increase accuracy, improve efficiency, and add value to the outcome. A comprehensive literature review is required to determine the utility of preoperative 3D planning software in guiding orthopedic surgeons for implant placement in rTSA. We hypothesize that implementation of 3D preoperative planning software in the setting of rTSA leads to high concordance with minimal deviation from the preoperative plan.

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Background And Hypothesis: The impact of preoperative fatty infiltration of specific rotator cuff muscles on the outcomes of reverse total shoulder arthroplasty (rTSA) has not been well defined. Preoperative fatty infiltration of the shoulder musculature will negatively affect rTSA outcomes.

Methods: A comprehensive literature review was conducted as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses using PubMed, Embase, OVID Medline, Scopus, Cinahl, Web of Science, and Cochrane databases for original, English-language studies evaluating effect of fatty infiltration of shoulder musculature on rTSA outcomes published from January 1, 2000 to present.

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