Klippel-Trenaunay syndrome and chiari I malformation. A case report and systematic review of the literature.

Introduction: Klippel-Trenaunay Syndrome (KTS) is a rare congenital condition characterized by vascular malformations, bone abnormalities, and limb overgrowth. The genetic basis of KTS is not fully understood, and the diagnosis relies on clinical features. Its clinical spectrum includes several neurosurgical diagnoses, such as cavernous hemangiomas, arteriovenous fistulas, and Chiari I malformation.

Improving surgical quality of care: learning from 8,331 surgical medical malpractice cases.

Objective: This study aimed to analyze the characteristics of surgical litigation cases and the risk factors that contribute to catastrophic compensation.

Methods: We downloaded and retrieved all cases related to surgical litigation cases from the China Jufaanli Database between 2008 and 2023. Multivariate logistic regression analysis was employed to identify independent risk factors that may contribute to catastrophic compensation.

Systemic Infection Affecting Multiple Sites After Near-Drowning: A Case Report.

() can cause fungal infections in near-drowning victims, and an increasing number of cases have been reported. However, cases of bone and joint infections caused by are rare. In this case, a 35-year-old otherwise healthy Chinese female presented with aspiration pneumonia and knee arthritis after accidentally falling into sewage and near-drowning and underwent macrogenomic second-generation sequencing of arthrocentesis fluid, which showed .

Postural control and shoulder rotators isokinetic strength in squash players with and without idiopathic scoliosis.

Idiopathic scoliosis is a postural deformity of the spine that not only changes the shape of the spine but may also alter postural control and muscle strength. Although this deformity is more common in some sports, it is not known whether the scoliosis athlete's balance and strength are altered. Balance and strength are essential to perform complex technical movements and prevent injuries.

General access to furan-substituted -difluoroalkenes enabled by PFTB-promoted cross-coupling of ene-yne-ketones and difluorocarbene.

Replacement of a carbonyl group with fluorinated bioisostere (, CF[double bond, length as m-dash]C) has been adopted as a key tactical strategy in drug design and development, which typically improves potency and modulates lipophilicity while maintaining biological activity. Consequently, new -difluoroalkenation reactions have undoubtedly accelerated this shift, and conceptually innovative practices would be of great benefit to medicinal chemists. Here we describe an expeditous protocol for the direct assembly of furan-substituted -difluoroalkenes PFTB-promoted cross-coupling of ene-yne-ketones and difluorocarbene.

Hidden blood loss in percutaneous endoscopic lumbar discectomy via the posterolateral approach.

Objectives: The study aimed to evaluate the hidden blood loss (HBL) and its possible risk factors in patients with lumbar disc herniation undergoing percutaneous endoscopic lumbar discectomy (PELD) via posterolateral approach.

Patients And Methods: The clinical data of 170 lumbar disc herniation patients (101 males, 69 females; mean age: 57.7±18.

Expression of lipid metabolism and cartilage degeneration-related factors in lumbar vertebral endplate Modic changes.

Objectives: This study aims to investigate the relationship between the expression of lipid metabolism and cartilage degeneration-related factors and Modic changes (MCs) of lumbar vertebral.

Patients And Methods: This prospective study included a total of 10 patients (6 males, 4 females; mean age: 60.4±8.

Hidden blood loss and risk factors in percutaneous endoscopic cervical discectomy.

Objectives: The study aimed to evaluate the hidden blood loss (HBL) and its possible risk factors in patients undergoing percutaneous endoscopic cervical discectomy (PECD) via posterior approach to better guide the management of perioperative anemia in patients.

Patients And Methods: The study retrospectively analyzed the clinical data of 60 patients (33 males, 27 females; mean age: 55.3±7.

Sarcopenia and risk of postoperative pneumonia: a systematic review and meta-analysis.

Background: Identifying patients at risk for postoperative pneumonia and preventing it in advance is crucial for improving the prognoses of patients undergoing surgery. This review aimed to interpret the predictive value of sarcopenia on postoperative pneumonia.

Methods: Science Citation Index Expanded (SCIE), Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from inception to August 2nd, 2023 to retrieve eligible studies.

Semi-segmented lumbar supernumerary hemivertebra resection in congenital scoliosis: a case report.

Background: Congenital scoliosis with progressive potential is a controversial subject in early-onset spinal deformities. The presence of a hemivertebra may produce severe spinal deformities. The evolution of a scoliotic curve in these cases is unpredictable and requires careful follow-up dependent on multiple variables, such as the location of the hemivertebra, the age of the patient at the time of diagnosis, and the degree of deformity already present in both sagittal and frontal planes.

Yield increment and transcriptome response caused by blue light treatment in Hericium coralloides.

Background: Hericium coralloides is a traditional edible and medicinal mushroom. Light is a key factor in forming fruiting bodies of fungi; however, the effects of different light on the yield and morphogenesis of H. coralloides are still unknown.

C-arm Free Unilateral Biportal Endoscopic Discectomy: A Technical Note.

This report presents a new unilateral biportal endoscopic (UBE) technique for lumbar disc herniation without C-arm guidance. Lumbar disc herniation requires surgical intervention when conservative methods fail. Shifts towards minimally invasive percutaneous endoscopic lumbar discectomy, including uniportal and biportal approaches, have been hindered by challenges such as steep learning curves and reliance on radiation-intensive C-arm guidance.

Treatment of Tenosynovial Giant Cell Tumor of the Cervical Spine with Postoperative Anti-RANKL Antibody (Denosumab) Administration.

Tenosynovial giant cell tumor (TGCT) is a fibrous histiocytic tumor originating in the synovial membrane. While cervical TGCT may not be considered a common diagnosis preoperatively because it is relatively rare, it has a high recurrence rate and should be considered. Total resection is preferable, but it can be challenging due to the risk of damaging the vertebral artery.

A one-day acceptance and commitment therapy workshop for the prevention of chronic post-surgical pain and long-term opioid use following spine surgery: Protocol for a pilot feasibility randomized controlled trial.

Background: Back pain is increasingly common, leading to more spine surgeries. While most people experience pain relief and improved function after surgery, many continue to suffer from chronic post-surgical pain (CPSP) with limited functional improvement. CPSP is often treated with opioids, raising concerns about misuse, poor functional outcomes, and broader public health impacts.

[The dynamics of 24-hour arterial pressure monitoring with manual and physical exposure to the cervical spine (A. Shishonin method) in patients with essential arterial hypertension].

Unlabelled: One of the most probable and controversial hypotheses regarding the etiology of essential arterial hypertension, is the increase in arterial pressure due to intracranial ischemia, for various reasons, particularly because of cervical osteochondrosis. The daily arterial blood pressure dynamics is of interest when attempting non-pharmacological induced correction of arterial pressure by manual and physical effects on the cervical spine.

Objective: To evaluate daily arterial pressure dynamics in patients with essential arterial hypertension who received non-pharmacological treatment by manual-physical action on the cervical spine (A.

[Impact of manual-physical correction method on aerobic metabolism processes in patients with essential arterial hypertension].

Unlabelled: Essential arterial hypertension (EAH) is a chronic non-communicable disease (CNCD), that develops in parallel with other pathologies of the CNCD group, the presence of which is promoted by hypodynamia with consequent disturbance of aerobic energy supply processes. These disorders include, in particular, degenerative-dystrophic processes of the locomotor system, comprising of the cervical spine. In turn, development of these processes can additionally worsen hemodynamics with disturbance of the oxygen transfer processes.

Offset sublaminar hook is an efficient tool for the prevention of distal junctional failure after kyphotic deformity correction.

Purpose: To assess the radiological outcomes and complications focusing on distal junctional failure (DJF) of adult spinal deformity patients who underwent thoracolumbar fixation with the use of offset sublaminar hooks (OSH) distally.

Methods: Retrospective review of a prospective, multicenter adult spinal deformity database (2 sites). Inclusion criteria were age of at least 18 years, presence of a spinal deformity with thoraco-lumbar instrumentation ending distally with OSH (pelvis excluded), with minimum 2 years of follow-up.

Scoliosis in Rett syndrome: a comparative analysis of postoperative complications.

Rett syndrome, a neurodevelopmental disorder primarily affecting females, presents unique challenges in managing associated scoliosis. This study aims to evaluate the efficacy and challenges of posterior spinal fusion (PSF) in Rett syndrome patients by analyzing postoperative complications. A retrospective cohort study was conducted using a large national database.

Validation of PROMIS-PI in a Lumbar Decompression Cohort Through Correlation to Established Pain and Disability Metrics.

Study Design: Retrospective review.

Objective: To validate using patient-reported outcome measurement information system-pain interference (PROMIS-PI) to assess outcomes in patients undergoing lumbar decompression surgery compared with well-established pain and disability measures.

Summary Of Background Data: PROMIS outcomes provide valuable information, but the PROMIS-PI measure has not been validated in lumbar decompression.

The impact of the muscle mass-to-fat ratio on the prognosis of patients undergoing pancreaticoduodenectomy for pancreatic cancer.

To evaluate the relationship between the muscle mass-to-fat ratio (MMFR) at the third lumbar spine (L3) and overall survival (OS) as well as related complications after pancreaticoduodenectomy (PD) for pancreatic cancer. Patients who underwent PD for pancreatic cancer between March 2017 and May 2023 at the Second Affiliated Hospital of Soochow University were included. Muscle mass and fat content at the L3 were measured by computed tomography.

Evaluating the use of sublingual sufentanil in patients with buprenorphine treatment who are undergoing ambulatory surgery: A Prospective Case Report.

Introduction: Opioid use disorder is a chronic illness with significant morbidity and mortality. Opioid agonists, like buprenorphine, are commonly used to prevent relapse. Recent changes in buprenorphine legislation are expected to increase prescription and guidelines recommend its continuation during the perioperative period for many patients.

Clinical Insights into Neurosyphilis Patients with Leptomeningeal Enhancement of Spinal Cord.

Background And Objectives: This study aims to report the clinical, biological, and imaging features of cross-sectional study of neurosyphilis patients with leptomeningeal enhancement of spinal cord. Here, 51 neurosyphilis patients with leptomeningeal enhancement of spinal cord positivity are described, offering a promise in terms of early diagnosis, thereby enabling timely detection and treatment.

Methods: We retrospectively included all neurosyphilis patients enrolled in this study from December 2019 to January 2024.

Non-cadaveric spine surgery simulator training in neurosurgical residency.

Background: Spine surgical training faces increasing challenges due to restricted working hours and greater sub specialization. Modern simulators offer a promising approach to teaching both simple and complex spinal procedures. This study evaluated the acceptance and efficacy of spine simulator training using a lumbar herniated disc model tested by 16 neurosurgical residents (PGY-1-6), and compared 3D and 2D teaching methods.

Biomechanical and clinical evaluation of PSO, modified PSO and VCR treating OVCF kyphosis: a finite element analysis.

Objective: To confirm the effect of surgery on spinal column biomechanics and to provide theoretical support for the advantages and disadvantages of different surgical methods and their clinical efficacy.

Methods: 33 continuous patients with no significant difference in risk factors related to the mechanical complications were enrolled in this retrospective study. Sagittal parameters were measured in the pre-, post-operative and following-up lateral radiograph of spine.