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An ALV-J isolate is responsible for spontaneous haemangiomas in layer chickens in China.
Avian Pathol
June 2011
The South China Agricultural University, Key Laboratory of Animal Disease Control and Prevention, The South China Agricultural University College of Veterinary Medicine, Guangzhou, 510642, China.
Subgroup J avian leukosis virus (ALV-J), first isolated in 1989, mainly induces tumours of myeloid leukosis (ML) in meat-type chickens. In 2006, ALV-J strain SCAU-HN06 was isolated from commercial layer hens with spontaneous haemangiomas in China. To confirm its role in the induction of haemangioma, we constructed a full-length copy of the proviral genome from SCAU-HN06, recovered virus from DF-1 cells detected by enzyme-linked immunosorbent assay, characterized its growth property and investigated its pathogenicity.
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