2 results match your criteria: "The Sixth Teaching Hospital of Xinjiang Medical University[Affiliation]"
iTRAQ-Based Proteomic Analysis of Spontaneous Achilles Tendon Rupture.
J Proteome Res
November 2024
Department of Osteopathy and Orthopedics (Ankle) Surgery, The Sixth Teaching Hospital of Xinjiang Medical University, No. 39 Wuxing South Road, Urumqi 830001, Xinjiang Uygur Autonomous Region, China.
Article Synopsis
- Spontaneous Achilles tendon rupture (SATR) mainly affects older adults with chronic injuries, but its cause and treatment options are still unclear.
- A study used iTRAQ proteomics to identify 2432 proteins in SATR patients, highlighting 307 differentially expressed proteins linked to key biological pathways, including those related to COVID-19 and extracellular matrix organization.
- Important proteins such as fibronectin and collagen types were found to be significantly affected in SATR tissues, indicating potential targets for improving diagnosis and treatment strategies.
iTRAQ-based proteomics reveals potential markers and treatment pathways for acute Achilles tendon rupture.
J Orthop Surg Res
November 2023
Department of Osteopathy and Orthopedics (Ankle) Surgery, The Sixth Teaching Hospital of Xinjiang Medical University, No. 39 Wuxing South Road, Ürümqi, 830001, Xinjiang Uygur Autonomous Region, China.
Background: Due to its limited blood supply and irregular mechanical loading, the Achilles tendon is the most frequently ruptured tendon. Despite the rising incidence of acute Achilles tendon rupture (AATR), the optimal treatment remains controversial. Missed diagnoses and delayed treatments lead to poor outcomes and limited treatment options.
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