4 results match your criteria: "The Seventh Clinical Medical School of Guangzhou University of Chinese Medicine[Affiliation]"

Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice, monkeys and humans.

Bone Res

January 2025

The Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, the Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, China.

Osteoarthritis (OA) is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms. Normal articular cartilage maintains at aneural state. Neuron guidance factor Semaphorin 3A (Sema3A) is a membrane-associated secreted protein with chemorepulsive properties for axons.

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Article Synopsis
  • * The analysis of 11 studies with 949 participants revealed significant gray matter abnormalities in specific brain regions, particularly the right postcentral gyrus, left precentral gyrus, and left cingulate gyrus, indicating that these changes may be linked to cognitive function deficits.
  • * Additionally, further investigations showed that the abnormal gray matter structure in the left cingulate gyrus is strongly associated with cognitive impairments, suggesting that these neuroanatomical changes could be used as potential imaging
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Background: Major depressive and social anxiety disorders have a high comorbidity rate and similar cognitive patterns. However, their unique and shared neuroanatomical characteristics have not been fully identified.

Methods: Voxel-based morphometric studies comparing gray matter volume between patients with major depressive disorder/social anxiety disorder and healthy controls were searched using 4 electronic databases from the inception to March 2022.

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Objective: The objective of this study is to evaluate the methodological quality of Tuina clinical practice guidelines (CPGs).

Methods: Computer searches of China National Knowledge Infrastructure (CNKI), Chinese Technical Periodicals (VIP), Wanfang Data Knowledge Service Platform, PubMed, Cochrane Library, Embase, and other databases were conducted to search for published guidelines on Tuina, with a search time frame from database creation to March 2021. Four evaluators independently used the Appraisal of Guidelines for Research and Evaluation II instrument to evaluate the quality of the included guidelines.

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