6 results match your criteria: "The Second Xiangya Hospital of the Central South University[Affiliation]"
Exploring structural and functional alterations in drug-naïve obsessive-compulsive disorder patients: An ultrahigh field multimodal MRI study.
Asian J Psychiatr
March 2023
Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, China; Department of Neurology of the Second Affiliated Hospital, Interdisciplinary Institute of Neuroscience and Technology, Key Laboratory of Medical Neurobiology of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, China; College of Biomedical Engineering and Instrument Science, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou, China; MOE Frontier Science Center for Brain Science and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, China. Electronic address:
Background: Brain structural and functional alterations have been reported in obsessive-compulsive disorder (OCD) patients; however, these findings were inconsistent across studies due to several limitations, including small sample sizes, different inclusion/exclusion criteria, varied demographic characteristics and symptom dimensions, comorbidity, and medication status. Prominent and replicable neuroimaging biomarkers remain to be discovered.
Methods: This study explored the gray matter structure, neural activity, and white matter microstructure differences in 40 drug-naïve OCD patients and 57 matched healthy controls using ultrahigh field 7.
Vitreous Herniation After a Blow to the Eye.
JAMA Ophthalmol
January 2017
The Second Xiangya Hospital of the Central South University, Changsha, Hunan, China.
Ameliorative effects of physcion 8-O-β-glucopyranoside isolated from Polygonum cuspidatum on learning and memory in dementia rats induced by Aβ1-40.
Pharm Biol
May 2016
Department of Neurology, The Second Xiangya Hospital of the Central South University, Changsha , China.
Context: Polygonum cuspidatum Sieb. Et Zucc. (Polygonaceae) has been traditionally used in folk medicine to treat various diseases.
View Article and Find Full Text PDFInduction of GADD34 Regulates the Neurotoxicity of Amyloid β.
Am J Alzheimers Dis Other Demen
May 2015
Department of Neurology, The Second Xiangya Hospital of the Central South University, Changsha, China.
The possible roles played by growth arrest and DNA damage-inducible gene 34 (GADD34) in Alzheimer's disease (AD) are so far less understood. In this study, we found that GADD34 was increased in the brains of AD transgenic J20 mice. The deposition of β-amyloid (Aβ) peptide is the main component of neurotic plaques in AD brain.
View Article and Find Full Text PDF[Comparison of two rat models of myocardial infarction].
Nan Fang Yi Ke Da Xue Xue Bao
November 2011
Department of Animal Center, The Second Xiangya Hospital of the Central South University, Changsha 410012, China.
Objective: To compare two rat models of myocardial infarction established by coronary artery ligation and harmonic scalpel method for their advantages, disadvantages and applications.
Methods: Sixty Sprague Dawley rats were randomly divided into sham-operated group, coronary artery ligation group and harmonic scalpel group. In the latter two groups, myocardial infarction was induced by ligation of the left anterior descending coronary artery and coagulation of the artery, respectively.
[Effect and mechanisms of rutaecarpine on treating atopic dermatitis in mice].
Sichuan Da Xue Xue Bao Yi Xue Ban
March 2011
Animal Laboatory, the Second Xiangya Hospital of the Central South University, Changsha 410011, China.
Objective: To study the effect of Rutaecarpine on the treatment of atopic dermatitis in mice.
Methods: DNCB was repeatedly applied on the back of NC/Nga mice to establish the animal model of atopic dermatitis. The mice without and with treatments with various does of Rutaecarpine were compared.