1 results match your criteria: "The Second Hospital affiliated to Zhejiang Chinese Medical College[Affiliation]"
[Effect of Salvia Miltiorrhiza Bunge on expression of osteoprotegerin in cultured human periodontal ligament fibroblasts].
Shanghai Kou Qiang Yi Xue
October 2010
The Second Hospital affiliated to Zhejiang Chinese Medical College, Hangzhou 310005, Zhejiang Province, China.
Article Synopsis
- The study aims to investigate how Salvia Miltiorrhiza Bunge affects the expression of osteoprotegerin (OPG) in human periodontal ligament fibroblasts.
- Researchers established a primary culture of these cells and assessed the impact of varying concentrations of the herb on OPG mRNA and protein levels using RT-PCR and ELISA.
- Results showed that exposure to Salvia Miltiorrhiza Bunge significantly increased both OPG mRNA expression after an hour and OPG protein secretion after twelve hours compared to a control group, indicating its potential to enhance OPG expression in these cells.