3 results match your criteria: "The Second Clinical Medical College of Fujian Medical University Quanzhou[Affiliation]"

Article Synopsis
  • The study investigates the link between MTHFR gene polymorphisms and gastric cardia adenocarcinoma (GCA), finding that the rs1801133 TT genotype is more common in patients than in controls.
  • A hospital-based case-control approach involved 330 GCA cases and 608 controls, utilizing genotyping to establish associations.
  • Results suggest that specific MTHFR genetic variants increase susceptibility to GCA, but further research is required to validate these findings.
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Peroxisome proliferator-activated receptor gamma (PPARG) is related to inflammation and plays an important role in the development of cancer. PPARG rs1801282 C>G polymorphism might influence the risk of cancer by regulating production of PPARG gene. Hence, a comprehensive meta-analysis was conducted to explore the association of PPARG rs1801282 C>G polymorphism with cancer susceptibility.

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The association between cyclooxygenase-2 (COX-2) -1195G>A (rs689466) polymorphism and cancer risk has been extensively explored. However, the results of previous studies remain controversial. To address this gap, we performed an updated meta-analysis of fifty-eight studies involving a total of 50,672 subjects.

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