172 results match your criteria: "The Second Affiliated Hospital of SUN YAT-SEN University[Affiliation]"

Article Synopsis
  • A study was conducted to evaluate the effectiveness of splenic autotransplantation combined with lower esophagus transaction anastomosis in treating portal hypertension due to liver cirrhosis.
  • Thirty-six patients were randomly assigned to either the splenic autotransplantation group or a control group that only underwent splenectomy, and various health markers were monitored before and after the procedures.
  • Results showed that patients in the splenic autotransplantation group had significantly higher levels of immune markers compared to the control group two months post-surgery, indicating it may help preserve immune function.
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Objective: To evaluate the clinical effect of local autogenous bone chips extended with allogeneic bone grafts in the posterolateral lumbar fusion.

Methods: From March 2005 to April 2007, 22 cases which underwent posterolateral lumbar fusion with allograft bone mixed with local autograft bone were analyzed retrospectively. The postoperative temperature, drainage flow and healing time of the incision were analyzed; postoperative lumbar pain was evaluated by visual analog scale (VAS) and JOA score; the postoperative efficacy was assessed by MacNab criteria and Oswestry disability index (ODI); the fusion rate was defined by Jorgenson fusion criteria.

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Purpose: This study was to analyze the magnetic resonance imaging (MRI) features of hepatocellular carcinoma (HCC) with bile duct tumor thrombi, and explore their correlations to histopathology to improve the accuracy of diagnosis.

Materials And Methods: 21 patients with pathologically confirmed HCC with bile duct tumor thrombi was performed with a superconducting 1.5-T MR imager within two weeks before operation.

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Background: Centromere protein H (CENP-H) is one of the fundamental components of the human active kinetochore. Recently, CENP-H was identified to be associated with tumorigenesis. This study was aimed to investigate the clinicopathologic significance of CENP-H in tongue cancer.

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Objective: Implantable cardioverter defibrillator (ICD) can effectively treat life-threatening ventricular arrhythmias. The most common side effect is inappropriate discharge. This study analyzes the incidence and causes of inappropriate discharges of ICD in our hospital.

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[Cochlear otosclerosis: 3 cases report and literature review].

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

January 2009

Department of Otolaryngology, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510120, China.

Objective: To investigate the clinical features in cochlear otosclerosis.

Method: Three cases with cochlear otosclerosis in our hospital from March 2007 to October 2008 were reported and the relevant literatures were reviewed. All the cases were confirmed the diagnose by temporal bone high-resolution CT scan (HRCT).

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Purpose: To evaluate the feasibility and outcome of a combined retroauricular and transoral approach for removing the submandibular gland.

Patients And Methods: Thirteen patients underwent removal of benign submandibular gland lesions (6 sialoadenitis with sialolithiasis, 4 chronic sialoadenitis, and 3 pleomorphic adenomas) using a combined retroauricular and intraoral approach.

Results: All 13 submandibular sialoadenectomies were successful and all of the wounds healed uneventfully.

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Background: Second branchial cleft cysts (also called cervical lymphoepithelial cysts) usually present in adulthood, and cosmesis of surgical access is an important issue. This study was performed to assess the feasibility and outcome of a retroauricular approach for removing second branchial cleft cysts.

Methods: Eight patients underwent removal of second branchial cleft cysts using a retroauricular approach.

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The purposes of this study were to determine the correlation between the expression of inducible nitric oxide synthase (iNOS) and vascular endothelial growth factor (VEGF) in ameloblastoma and to examine the relationships of this expression to angiogenesis and the clinical and biological behaviors of the tumor. Immunohistochemical staining with streptavidin peroxidase was used to analyze iNOS and VEGF expression, and CD34 was used to evaluate microvascular density (MVD) in 35 ameloblastomas (24 primary tumors and 11 recurrences) and 5 malignant ameloblastomas. Ten odontogenic keratocysts (OKCs) served as controls.

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Mucous membrane hemangiomas of the lip are common benign vascular tumors of infancy. This clinical study evaluated the efficacy and safety of liquid nitrogen cryotherapy of mucous membrane hemangiomas of the lip in early infancy. It was a retrospective review of 127 pediatric patients with hemangiomas involving the lips who underwent liquid nitrogen cryotherapy under inhalation general anesthesia with sevoflurane.

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Objective: To summarize the reasons for bile duct injury (BDI) after laparoscopic cholecystectomy (LC), and to determine the effect of multiple treatment after BDI.

Methods: A retrospective cohort study was performed. The medical records of 110 patients diagnosed with BDI after LC from October 1993 to November 2007, in ten large hospitals in Guangdong of China, were reviewed.

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Objective: To compare the clinical therapeutic effect and complications of laparoscopic radical cystectomy with orthotopic ileal neobladder (LRC-INB) with open radical cystectomy with orthotopic ileal neobladder (ORC-INB).

Methods: A total of 171 patients were evaluated, including 63 cases with ORC-INB and 108 cases with LRC-INB from June 1994 to May 2007 at our institution. The parameters analyzed included perioperative data, postoperative complications, new bladder function and effect of tumor control.

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Activator protein-1 (AP-1), which is a transcription factor, is implicated in the transcriptional regulation of a wide range of genes that participate in cell proliferation and extracellular matrix production. This investigation was performed to test the hypothesis that transfection of cardiac fibroblasts (CFs) with sufficient amounts of decoy oligodeoxynucleotides (ODNs) containing the AP-1-binding site would result in binding to the transfactor AP-1, which would thereby prevent CF proliferation and matrix metalloproteinase (MMP) expression. CFs from Sprague-Dawley rat hearts were cultured and exposed to different concentrations of xanthine + xanthine oxidase (XXO) and AP-1 decoy ODNs.

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Objective: The low rate of engraftment in children with beta-thalassemia has seriously restricted the popularity of the hematopoietic stem cell transplantation (HSCT). Panel reactive antibody (PRA) has been regarded as one of the important factors for the success of kidney transplantation. Poly-transfusion before transplantation is associated with the production of PRA.

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Objective: To evaluate the value of radiofrequency ablation in the treatment of small hepatocellular carcinoma (HCC).

Methods: MEDLINE (1966 - 2008), EMBASE (1966 - 2008), CBMdisc (1978 - 2008) were searched. The Cochrane Library, Evidence Base Medicine Reviews (Ovid Edition), Cancerlit (1993 - 2008) and so on, date of last search: 30 January 2008.

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Background & Objective: Soft tissue desmoid-type fibromatosis is a type of benign, infiltrative tumors which are rarely seen. This study was to analyze CT and MR manifestations and pathologic features of soft tissue desmoid-type fibromatosis to improve its diagnostic accuracy.

Methods: A total of 34 soft tissue desmoid-type fibromatosis from 29 patients, including 20 primary and 14 recurrent tumors were analyzed.

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Article Synopsis
  • * The study analyzed miRNA expression in 10 pairs of endometrioid adenocarcinoma and adjacent normal endometrial tissues, identifying 17 miRNAs with increased and 6 with decreased expression in cancer samples.
  • * Key findings included high levels of miR-205, miR-449, and miR-429, along with reduced levels of miR-204, miR-99b, and miR-193b in cancer tissues, which could aid future research on their role in cancer and their potential as diagnostic or treatment options. *
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Background: This study revisited the ovarian volume (OV) as one of the diagnostic criteria for Chinese adolescents with polycystic ovary syndrome (PCOS). It is unknown whether the threshold of 10 cm(3) for the OV, chosen at the PCOS international consensus in 2003, was optimal for Chinese PCOS adolescents or not.

Methods: 69 adolescent PCOS patients and 26 controls were involved in this study.

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Objective: This study presents an effective repair method for the hemimandibular and oral defects produced during the ablation of advanced oral malignant tumours.

Methods: Nine patients (five males and four females ranging in age from 18 to 74 years; mean age 51.3 years) with advanced oral malignant tumours were treated at our institution.

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Background & Objective: Liver metastasis is the most common cause of death due to colorectal cancer. Above 50% colorecal cancer patients have liver metastasis. This study was to investigate the effect of transfection of arresten gene on liver metastasis from human colorectal cancer (LoVo) xenografts in nude mice.

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[Clinical analysis on syphilis with sensorineural deafness].

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

July 2008

Department of Otorhinolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510120, China.

Objective: To investigate the clinical presentation, diagnosis and therapy of syphilis with sensorineural deafness.

Method: Three patients of syphilis with sensorineural deafness were analyzed including the clinical manifestation, serum and therapy response.

Result: Three patients of syphilis with sensorineural deafness: 2 cases with rapid plasma reagin (RPR) and treponema pallidum particle agglutination (TPPA) positive, 1 case with RPR negative and TPPA positive; 2 cases had been diagnosed with syphilis and treated once; 2 cases with sudden sensorineural deafness and tinnitus, 1 case with tinnitus and high-frequency hearing loss.

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Objective: To observe the effect of electroacupuncture on recovery of urinary bladder function after radical hysterectomy.

Methods: One hundred and ten cases were randomly divided into an electroacupuncture (EA) group and a control group, 55 cases in each group. In the control group, the urinary tube was placed and kept with routine method and the urinary bladder was rinsed, and from the eighth day the abdomen was radiated with TDP, 30 min each day, for 5 days.

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Objective: The objective was to study the association between B-type natriuretic peptide (BNP) and tumour markers and heart failure (HF) to evaluate the value of BNP and carbohydrate antigen 125 (CA125) in HF patients.

Design And Setting: A university hospital-based cross-over study of 285 subjects (157 men and 128 women) in HF, chronic obstructive pulmonary disease (COPD), mild-mid pulmonary hypertension patients and control subjects.

Results: CA125 and BNP were significantly higher in the HF group than in the non-HF group and in severe HF than in mild HF (P < 0.

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Objective: To assess the value of ovarian volume and follicle number in the diagnosis of polycystic ovary syndrome (PCOS) in a Chinese population.

Methods: This study included 432 women with PCOS selected using the National Institutes of Health criteria, who were compared with 153 age-matched women as controls. All participants were given a transvaginal or transrectal ultrasound scan during day 3-5 of the menstrual cycle (for regularly menstruating women) or randomly (for oligomenorrheic or amenorrheic women).

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Objective: To observe the clinical effect of gengnianningshentang on the treatment of the climacteric syndrome of fever due to yin-deficiency.

Methods: 108 patients with climacteric syndrome of fever due to yin-deficiency were divided randomly into treatment group (76 cases)and control group (32 cases). Treatment group was treated by gengnianningshentang, and control group was treated by Vitamin E for 3 months.

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