1 results match your criteria: "The Scientific Center of Children's Health[Affiliation]"
A Pilot Study of Confocal Laser Endomicroscopy to Predict Barrier Dysfunction and Relapse in Pediatric Inflammatory Bowel Disease.
J Pediatr Gastroenterol Nutr
June 2016
*Endoscopy Department, The Scientific Center of Children's Health, Russian Academy of Medical Sciences (RAMS)†Children's Clinical and Research Institute of Emergency Surgery and Trauma, Moscow, Russian Federation‡Division of Gastroenterology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock§Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA||Institute of Pediatric Surgery Department, The Scientific Center of Children's Health, Russian Academy of Medical Sciences (RAMS), Moscow, Russian Federation.
Objectives: Probe-based confocal laser endomicroscopy (pCLE) is a novel imaging modality that enables virtual optical biopsy in vivo. Loss of barrier function of the small bowel observed via pCLE as increased density of epithelial gaps (extrusion zones left in the intestinal lining after cells are shed) is predictive of relapse in adult patients with inflammatory bowel disease (IBD). This study aims to determine whether such observations on pCLE are similarly predictive of disease relapse in pediatric patients with IBD.
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