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Article Synopsis
  • Oesophagogastric cancer surgery outcomes are generally poor, leading researchers to investigate the effectiveness of cardiopulmonary exercise testing (CPET) in predicting postoperative results, especially after neoadjuvant treatments.
  • A study included 611 patients from seven UK centers, analyzing the relationship between peak oxygen uptake (VO peak) and one-year survival, finding no significant correlation, but noting that anaerobic threshold measures related to ideal body weight were predictive of three-year survival.
  • Key factors influencing survival included tumor characteristics and major complications, with specific CPET metrics showing some predictive value but not universally across the entire cohort.
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Background: Neoadjuvant therapy reduces fitness, muscle mass, and quality of life (QOL). For patients undergoing chemotherapy and surgery for esophagogastric cancer, maintenance of fitness is paramount. This study investigated the effect of exercise and psychological prehabilitation on anaerobic threshold (AT) at cardiopulmonary exercise testing (CPET).

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