3 results match your criteria: "The Royal Melbourne Hospital-The Florey Institute for Neuroscience and Mental Health[Affiliation]"
Sex-Based Differences in Endovascular Thrombectomy Outcomes for Large Ischemic Stroke: A SELECT2 Subanalysis.
Stroke
January 2025
Neurology, Stroke, University Hospital Cleveland Medical Center - Case Western Reserve University, OH. (A.O., C.S., A.S.).
Background: Several social and biological factors are shown to differentially affect stroke outcomes between men and women. We evaluated whether clinical outcomes and endovascular thrombectomy (EVT) treatment effects differed between the sexes in patients presenting with large ischemic stroke.
Methods: The SELECT2 trial (A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke) was a randomized controlled trial assessing the efficacy and safety of EVT in patients with large strokes across the United States, Canada, Europe, Australia, and New Zealand between October 2019 and September 2022.
Anticoagulation Use and Endovascular Thrombectomy in Patients with Large Core Stroke: A Secondary Analysis of the SELECT2 Trial.
Ann Neurol
November 2024
Department of Neurology and Stroke, University Hospital Cleveland Medical Center-Case Western Reserve University, Cleveland, OH, USA.
Endovascular thrombectomy (EVT) safety and efficacy in patients with large core infarcts receiving oral anticoagulants (OAC) are unknown. In the SELECT2 trial (NCT03876457), 29 of 180 (16%; vitamin K antagonists 15, direct OACs 14) EVT, and 18 of 172 (10%; vitamin K antagonists 3, direct OACs 15) medical management (MM) patients reported OAC use at baseline. EVT was not associated with better clinical outcomes in the OAC group (EVT 6 [4-6] vs MM 5 [4-6], adjusted generalized odds ratio 0.
View Article and Find Full Text PDFCurrent State of Evidence for Neuroimaging Paradigms in Management of Acute Ischemic Stroke.
Ann Neurol
June 2024
The Royal Melbourne Hospital-The Florey Institute for Neuroscience and Mental Health, Medicine and Neurology, Parkville, Australia.
Article Synopsis
- - Stroke is a major concern for patients with sudden neurological symptoms in the emergency room, and imaging techniques like CT and MRI are essential for diagnosis and treatment decisions
- - Non-contrast CT or MRI helps distinguish between ischemic strokes and bleeding in the brain, which is critical for timely treatment, including thrombolytics
- - Advanced imaging can identify blockages in blood vessels and assess brain tissue health, guiding more complex treatments like endovascular thrombectomy and informing future developments in stroke imaging protocols