47 results match your criteria: "The Royal College of Obstetricians and Gynaecologists[Affiliation]"
Recent increase in infant pertussis cases in Europe and the critical importance of antenatal immunizations: We must do better…now.
Int J Infect Dis
September 2024
Immunisation and Countermeasures Division, UK Health Security Agency, London, UK.
Article Synopsis
- * This decline in immune stimulation has increased susceptibility in populations, amplifying the usual cyclical peaks of the disease.
- * Maternal immunization is effective in protecting infants under three months and highlights the importance of timely vaccination for both mothers and infants to prevent severe disease.
Pregnant women and measles: we need to be vigilant during outbreaks.
EClinicalMedicine
June 2024
Immunisation and Countermeasures Division, UK Health Security Agency, UK.
A number of countries including the UK are currently experiencing large outbreaks of measles affecting mainly young children but also adolescents and young adults. Women of childbearing age are a particular group of concern because the 1988 Wakefield Lancet paper, which falsely asserted a connection between the MMR vaccine and autism, was associated with a large and sharp decline in childhood MMR uptake over several years. This has left large cohorts of non-immune adolescents and young adults (born between 1998 and 2004), including young women who are now of childbearing age and remain susceptible to measles as well as rubella.
View Article and Find Full Text PDFAwareness and Attitude Toward Epidural Analgesia During Labor Among Pregnant Women in Taif City: A Hospital-Based Study.
Cureus
November 2023
Department of Obstetrics and Gynaecology, Prince Sultan Military Hospital, Taif, SAU.
Objectives This study aimed to investigate the awareness and attitudes towards epidural analgesia (EA) among pregnant women in Taif City, Saudi Arabia. The rationale was to identify potential barriers to the acceptance and use of EA, which is an effective pain management option during labor. Methods We conducted a cross-sectional survey at a single healthcare center in Taif City.
View Article and Find Full Text PDFA call to action: the global failure to effectively tackle maternal mortality rates.
Lancet Glob Health
August 2023
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London, UK; Immunisation and Countermeasures Division, UK Health Security Agency, London, UK.
Risk factors for a serious adverse outcome in neonates: a retrospective cohort study of vaginal births.
BJOG
November 2023
Department of Public Health and Primary Care / Cardiovascular Epidemiology Unit, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.
Objective: To investigate the hypothesis that risk factors in addition to an abnormal fetal heart rate pattern (aFHRp) are independently associated with adverse neonatal outcomes of labour.
Design: Observational prospective cohort study.
Setting: 17 UK maternity units.
Do not forget pregnant and post-partum women during group A streptococcal disease outbreaks.
Lancet Microbe
June 2023
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London, SW17 0QT, UK; Immunisation and Countermeasures Division, Public Health England, London, UK.
Treatment and prevention of mpox in pregnant people and young children.
Lancet Infect Dis
April 2023
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London SW17 0QT, UK; Immunisation and Countermeasures Division, Public Health England, London, UK; British Paediatric Surveillance Unit, Royal College of Paediatrics and Child Health, London, UK.
Listeria outbreaks cause maternal and perinatal mortality and morbidity: we must do better.
Lancet Microbe
April 2023
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London SW17 0QT, UK; Immunisation and Countermeasures Division, UK Health Security Agency (Public Health England), London, UK; British Paediatric Surveillance Unit, Royal College of Paediatrics and Child Health, London, UK.
The need for better diagnostics to support diagnosis and surveillance in monkeypox endemic countries.
Lancet Microbe
February 2023
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London, UK; Immunisation and Countermeasures Division, UK Health Security Agency, London, UK; British Paediatric Surveillance Unit, Royal College of Paediatrics and Child Health, London, UK.
Monkeypox in children: Update on the current outbreak and need for better reporting.
Lancet Reg Health Eur
November 2022
Paediatric Infectious Diseases Research Group, Institute of Infection and Immunity, St George's University of London, London, United Kingdom.
Monkeypox and pregnancy: time for global surveillance and prevention strategies.
Lancet
October 2022
The Royal College of Obstetricians and Gynaecologists, London, UK; University College London Hospitals NHS Foundation Trust, London, UK.
Monkeypox in pregnancy: update on current outbreak.
Lancet Infect Dis
November 2022
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London SW17 0QT, UK; Immunisation and Countermeasures Division, Public Health England, London, UK; British Paediatric Surveillance Unit, Royal College of Paediatrics and Child Health, London, UK.
Call for a unified approach to Monkeypox infection in pregnancy: Lessons from the COVID-19 pandemic.
Nat Commun
August 2022
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London, UK.
In the current monkeypox outbreak, vaccination and treatment of pregnant women are recommended only if the benefits outweigh risks, but the extremely sparse data available limit evidence-based recommendations. We must facilitate a unified consensus approach to rapidly collect robust data. Two years into the COVID-19 pandemic, monkeypox has emerged as yet another challenge to the mother-fetus dyad, potentially placing both at risk, if exposed.
View Article and Find Full Text PDFMonkeypox vaccines in pregnancy: lessons must be learned from COVID-19.
Lancet Glob Health
September 2022
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London, UK; Immunisation and Countermeasures Division, Public Health England, London, UK; British Paediatric Surveillance Unit, Royal College of Paediatrics and Child Health, London, UK.
Monkeypox and pregnancy: what do obstetricians need to know?
Ultrasound Obstet Gynecol
July 2022
Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St George's University of London, London, UK.
Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy.
Nat Commun
May 2022
Fetal Medicine Unit, St George's Hospital, St George's University of London, London, UK.
Safety and effectiveness of COVID-19 vaccines during pregnancy is a particular concern affecting vaccination uptake by this vulnerable group. Here we evaluated evidence from 23 studies including 117,552 COVID-19 vaccinated pregnant people, almost exclusively with mRNA vaccines. We show that the effectiveness of mRNA vaccination against RT-PCR confirmed SARS-CoV-2 infection 7 days after second dose was 89·5% (95% CI 69·0-96·4%, 18,828 vaccinated pregnant people, I = 73·9%).
View Article and Find Full Text PDFThe effect of the delta SARS-CoV-2 variant on maternal infection and pregnancy.
iScience
May 2022
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
A greater proportion of pregnant women with COVID-19 have mild disease compared with their non-pregnant counterparts. Paradoxically, however, they are at higher risk of developing severe disease, requiring respiratory support and admission to intensive care. The delta SARS-Cov-2 variant is associated with increased risk of hospitalization and morbidity in unvaccinated pregnant populations.
View Article and Find Full Text PDFPotential role of neurofilament in COVID-19 and preeclampsia.
Cell Rep Med
January 2022
Fetal Medicine Unit, St George's Hospital, St George's University of London, London, UK.
Neurofilament light (NFL) is a promising circulating biomarker in preeclampsia and COVID-19, even without evident neurological complications. Several pathways might contribute to the elevated serum NFL levels seen in both pathologies. Future studies will determine whether NFL is a long COVID marker and delineate NFL's role in COVID-19-associated preeclampsia.
View Article and Find Full Text PDFCOVID-19 and stillbirth: direct vs indirect effect of the pandemic.
Ultrasound Obstet Gynecol
March 2022
University College London Hospitals NHS Foundation Trust, London, UK.
Does COVID-19 cause pre-eclampsia?
Ultrasound Obstet Gynecol
February 2022
University College London Hospitals NHS Foundation Trust, London, UK.
COVID-19 vaccination in pregnancy-number needed to vaccinate to avoid harm.
Lancet Infect Dis
December 2021
Fetal Medicine Unit, St George's Hospital, St George's University of London, London SW17 0QT, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London SW17 0QT, UK. Electronic address:
An internally validated prediction model for critical COVID-19 infection and intensive care unit admission in symptomatic pregnant women.
Am J Obstet Gynecol
March 2022
Fetal Medicine Unit, St George's Hospital, St George's University of London, London, United Kingdom; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, United Kingdom. Electronic address:
Background: Pregnant women are at an increased risk of mortality and morbidity owing to COVID-19. Many studies have reported on the association of COVID-19 with pregnancy-specific adverse outcomes, but prediction models utilizing large cohorts of pregnant women are still lacking for estimating the risk of maternal morbidity and other adverse events.
Objective: The main aim of this study was to develop a prediction model to quantify the risk of progression to critical COVID-19 and intensive care unit admission in pregnant women with symptomatic infection.
SARS-CoV-2 vaccination in pregnancy: a unique opportunity for equity.
Lancet
September 2021
Fetal Medicine Unit, St George's Hospital, St George's University of London, Cranmer Terrace, London SW17 0RE, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, Cranmer Terrace, London, UK. Electronic address:
Addressing inequality in fertility treatment.
Lancet
August 2021
Race Equality Taskforce, The Royal College of Obstetricians and Gynaecologists, London, UK; Queen Charlotte's and Chelsea Hospital, Imperial Healthcare NHS Trust, London W12 0HS, UK. Electronic address: