6 results match your criteria: "The Research Institute of Galilee Medical Center[Affiliation]"
When did the confusion between vulvodynia and vaginismus start?
J Turk Ger Gynecol Assoc
August 2024
The Research Institute of Galilee Medical Center, Galilee Medical Center, Nahariya, Israel.
Changing the paradigm: Elimination - Not only of cervical cancer.
Gynecol Oncol Rep
August 2024
Department of Obstetrics & Gynecology, University of Iowa, Iowa City, Iowa, USA.
The WHO's initiative to eliminate cervical cancer by 2030 does not address the increasing incidence of vulvar, anal, and oropharyngeal cancers linked to high-risk HPV. Currently, the prevention of these three cancers faces various obstacles, such as a lack of specialized screening programs, well-defined management guidelines, and widespread public awareness. Without any interventions, the incidence of these three cancers will likely rise in the upcoming years, increasingly affecting younger individuals.
View Article and Find Full Text PDFIs Vulvodynia Associated With an Altered Vaginal Microbiota?: A Systematic Review.
J Low Genit Tract Dis
January 2024
The Research Institute of Galilee Medical Center, Galilee Medical Center, Nahariya, Israel.
Introduction: Vulvodynia is defined as vulvar pain of at least 3 months' duration, without clear identifiable cause, which may have potential associated factors. It can have a significant impact on women's quality of life due to a combination of physical pain, emotional distress, and limited treatment options. Despite affecting a considerable number of women worldwide, the causes and underlying mechanisms of vulvodynia remain poorly understood.
View Article and Find Full Text PDFBlocking the ErbB pathway during adolescence affects the induction of anxiety-like behavior in young adult maternal immune activation offspring.
Pharmacol Biochem Behav
January 2023
Psychobiology Research Laboratory, Mazor Mental Health Center, Akko, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel. Electronic address:
Epidemiological and experimental evidence demonstrates that maternal exposure to infection during gestation increases the offspring's risk of developing schizophrenia and other neurodevelopmental disorders. In addition, the NRG-ErbB4 signaling pathway is involved in brain development and neuropsychiatric disorders. Specifically, this pathway modulates the dopaminergic and GABAergic systems and is expressed in the early stages of prenatal development.
View Article and Find Full Text PDFChanges in the Vaginal Microbiota of Women With Secondary Localized Provoked Vulvodynia.
J Low Genit Tract Dis
October 2022
Department of Obstetrics and Gynecology, Hospital Lusíadas Lisboa, Porto, Portugal.
Objective: The etiology of localized provoked vulvodynia (LPV) remains unknown, but observations suggest the involvement of the vaginal microbiota. We examined the vaginal microbiota of women with LPV and healthy controls, upon after a low-oxalate diet (LOD).
Materials And Methods: A total of 9 women diagnosed with secondary LPV and 21 healthy controls were recruited from the Galilee Medical Center in Israel and subjected to prospective evaluations of their vaginal microbiota.
Article Synopsis
- - Provoked vulvodynia (PV) causes vulvar pain and is linked to inflammation, increased mast cells, and higher sensitivity in the vulva; this study aims to investigate these factors using a rat model.
- - The researchers measured vulvar sensitivity over 5 months after inducing inflammation in rats and looked at levels of glutamate and nerve growth factor (NGF), as well as changes in sensory neurons.
- - Results showed that inflamed rats had lasting sensitivity, increased levels of NGF and glutamate, and heightened mast cell activity, suggesting that vulvar pain is driven by these inflammatory responses and can be modulated by the mast cell stabilizer ketotifen fumarate.