1 results match your criteria: "The Research Center for Obstetrics[Affiliation]"
The role of genetic and autoimmune factors in premature ovarian failure.
J Assist Reprod Genet
June 2013
The Research Center for Obstetrics, Gynecology and Perinatology, the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
Purpose: To identify the role of both genetic (number of CGG repeats in the FMR1 gene) and autoimmune factors (anti-ovarian antibodies) in premature ovarian failure (POF).
Methods: In cross-sectional study, 78 women with POF were divided into 3 groups by the number of CGG repeats (less than 28, 28-36, more than 36) in any of the FMR1 gene alleles. We performed the detection of skewed X-chromosome inactivation, CGG repeats in the FMR1 gene, anti-ovarian antibodies (AOA) and sex hormones tests.