1 results match your criteria: "The Physical and Chemical Research Institute (RIKEN)[Affiliation]"
Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis.
Autoimmun Rev
April 2005
Laboratory for Rheumatic Diseases, SNP Research Center, The Physical and Chemical Research Institute (RIKEN), 1-7-22 Suehirocho, Tsurumiku, Yokohama, Kanagawa 230-0045, Japan.
Anticitrullinated peptide antibodies seem to be one of the most clinically reliable serologic markers for rheumatoid arthritis (RA). A genetic approach revealed that one of the citrullinating enzymes has a RA-susceptible variant. Peptidyl citrullination alters the chemical character of peptides and, subsequently, their antigenicity as well.
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