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[Determination of serum IL-23 and its significance in patients with severe chronic hepatitis B].

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi

April 2012

Department of Internal Medicine, The People's Hospital of Xiantao City, Hubei Province, Xiantao 433000, China.

Objective: To investigate the level of the serum IL-23 and its correlation with serum biochemical indices of liver function tests and HBV DNA load in patients with chronic severe hepatitis B.

Methods: Fifty patients with chronic severe hepatitis B (severe hepatitis group) and 18 healthy controls (control group) were enrolled in the study. The serum IL-23 expression level was detected by ELISA method.

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