178 results match your criteria: "The People's Hospital of Leshan.[Affiliation]"

The effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I.

Genes Dis

March 2025

Department of Cardiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, China.

Article Synopsis
  • Aging increases the risk of cardiovascular diseases, particularly cardiac diastolic dysfunction (CDD), which can lead to heart failure with preserved ejection fraction (HFpEF) in older adults.
  • Research indicates that green tea catechins, specifically epigallocatechin gallate (EGCG), may help improve cardiovascular issues related to aging in both animal models and humans, yet studies on its long-term effects on CDD are limited.
  • In this study, older mice treated with EGCG showed a prevention of aging-related CDD and improvements in heart function, attributed to enhanced expression of cardiac troponin I (cTnI) and reduced mitochondrial damage through the inhibition of histone deacetylase 1 (HDAC1).
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Removal of a parotid foreign body by endoscopic surgery-a case report.

Int J Surg Case Rep

December 2024

Department of Thyroid, Head, Neck and Maxillofacial Surgery, the Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, Sichuan 621000, PR China. Electronic address:

Backgrounds: Parotid foreign bodies are not common. The majority of cases are caused by trauma. The clinical presentation, symptoms, and duration of discomfort vary among patients and may be challenging to treat.

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Self-Reported Symptoms of Obstructive Sleep Apnea are Associated with Increased Risk of Kidney Stones: A Cross-Sectional Study from NHANES 2015-2020.

Nat Sci Sleep

December 2024

Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610064, People's Republic of China.

Objective: To investigate whether self-reported symptoms of obstructive sleep apnea (OSA), including snoring, snorting/stopping breathing, and sleepiness, are associated with increased risk of kidney stones.

Methods: This cross-sectional study was conducted based on the 2015-2020 National Health and Nutrition Examination Survey (NHANES). Self-reported symptoms of OSA and history of kidney stones were diagnosed via questionnaires.

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Proteomic and metabolomic exploration in relapse acute myeloid leukemia bone marrow supernatant combined with genetic characteristics.

BMC Cancer

December 2024

Department of Laboratory Medicine, Chongqing General Hospital, Chongqing University, No.118, Xingguang Avenue, Liangjiang New Area, Chongqing, 401147, China.

Object: Aim to investigate the multi-omic characteristics of the bone marrow supernatant of relapsed acute myeloid leukemia (AML) and search for proteins and metabolites associated with relapse.

Methods: A total of 40 bone marrow supernatant from 7 patients with relapsed AML and 33 patients with non-relapsed AML were collected for proteomics and metabonomics analysis. Unsupervised clustering was used to discover the characteristics of proteins and metabolites.

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Background: Research investigating the potential impact of postoperative adjuvant chemotherapy cycles on patients with lymph node-negative gastric cancer following neoadjuvant chemotherapy is currently sparse. This study aims to explore the effect of adjuvant chemotherapy cycles on the prognosis of this specific patient group.

Patients And Methods: We analyzed clinicopathological data from patients at four institutions between 2010 and 2020.

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Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder closely associated with chronic inflammation. Curcumin, a polyphenolic lipophilic compound, has been shown to improve the intestinal mucosal barrier and reduce low-grade systemic inflammation. This study aimed to assess the effects of curcumin on attenuation of PCOS in a mouse model and to explore the underlying mechanisms involved.

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Article Synopsis
  • This study aims to assess how the combination of Lactobacillus acidophilus and montmorillonite powder affects inflammation in children with rotavirus enteritis (RVE).
  • A total of 94 children were divided into two groups, one receiving standard treatment plus montmorillonite and the other receiving standard treatment plus Lactobacillus for five days.
  • Results showed that the Lactobacillus group had a higher recovery rate, shorter symptom relief times, and lower inflammatory markers, though adverse reactions were similar in both groups.
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A deep neural network improves endoscopic detection of laterally spreading tumors.

Surg Endosc

November 2024

Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Institute of Gastroenterology of Guangdong Province, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Colorectal cancer (CRC) is the malignant tumor of the digestive system with the highest incidence and mortality rate worldwide. Laterally spreading tumors (LSTs) of the large intestine have unique morphological characteristics, special growth patterns and higher malignant potential. Therefore, LSTs are a precancerous lesion of CRC that could be easily missed.

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Objective: Bacterial vaginosis is a disease caused by vaginal microecology disorder, which seriously affects female health. At present, there are many drugs to treat BV, and this study aims to compare the efficacy and safety of multiple drugs for BV through a network meta-analysis (NMA).

Methods: All studies were sourced from PubMed and Embase databases from the establishment date to April 13, 2023.

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Background: The effectiveness of the anastomosis method for laparoscopic left colectomy (LLC) remains inconclusive. Thus, a systematic review and meta-analysis were conducted to compare the outcomes between intraperitoneal anastomosis (IPA) and extraperitoneal anastomosis(EPA)in LLC.

Methods: PubMed, Embase, the Cochrane Library, CNKI, and WanFangData were systematically searched for relevant literature.

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Article Synopsis
  • Air pollution is a significant contributor to stroke-related deaths and health issues, with the study analyzing its global impact from 1990 to 2021.
  • In 2021, there were nearly 2 million deaths and around 45 million disability-adjusted life years (DALYs) attributed to air pollution-related strokes, particularly affecting older males in regions like Central Africa.
  • Despite an overall decline in age-standardized rates of stroke deaths, the burden remains high, especially in certain regions, with predictions suggesting a gradual decrease in rates through 2040.
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Article Synopsis
  • - New graduate nurses in China face safety challenges due to a lack of knowledge and clinical practice, prompting the implementation of a standardized training strategy that also considers personality traits to enhance training effectiveness.
  • - A personality test using the BFI-2 scale was conducted among nursing students, with data gathered on personality traits, self-efficacy, and theoretical exam results before and after training, analyzed using SPSS software.
  • - Results indicated that while theoretical exam scores did not change significantly with different personality traits, conscientiousness scored highest in both skill assessments and professional self-efficacy, while negative emotionality resulted in the lowest scores, highlighting significant correlations between personality and training outcomes.
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Immune checkpoint inhibitor therapy for functional cure of hepatitis B in cancer patients: a promising strategy?

J Hepatol

September 2024

Department of General Surgery (Hepatopancreatobiliary surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, 646000, China; Academician (Expert) Workstation of Sichuan Province, Metabolic Hepatobiliary and Pancreatic Diseases Key Laboratory of Luzhou City, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, 646000, China. Electronic address:

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Purpose: Dermoid excision combined with lamellar keratoplasty was one of the most common surgical techniques for corneal dermoid. Due to the huge shortage of corneal donors, small incision lenticule extraction (SMILE) derived lenticules might be the novel and feasible corneal grafts instead of traditional corneal donors. Therefore, we tried to use FG boned multi-layer lenticules as grafts in the treatment of corneal dermoid.

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Aim: Differentiated thyroid cancer (DTC) is a type of thyroid cancer with rapid progression and poor prognosis, and effective clinical treatment is of great significance in safeguarding the prognostic health of patients. Therefore, we assessed the effect of modified Miccoli's thyroidectomy on stress responses and quality of life in DTC patients, aiming to provide a more comprehensive reference for future DTC treatment.

Methods: This study retrospectively analyzed 100 DTC patients admitted to our hospital from January 2023 to December 2023.

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Objective: This study aimed to explore the optimal dose of dexmedetomidine as a 0.59% ropivacaine adjuvant for epidural anesthesia on perioperative hemodynamics and anesthesia efficacy in patients undergoing great saphenous varicose vein surgery.

Methods: A total of 90 patients were randomly divided into three groups: 0.

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A 72-year-old female who had received emergent endoscopic cyanoacrylate (CYA) injection for bleeding gastric varices (GV) two month before was readmitted due to recurrence of melena. Current gastroscopy verified the type-2 GV (GOV-2) according to Sarin's classification with stigmata of recent bleeding. Endoscopic ultrasound (EUS) identified the largest varix of 8.

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Objective: To investigate the current situation of child safety seat use and children's cognition of safe riding in Leshan City, and to provide a basis for the promotion and application of child safety seats in Leshan City.

Methods: From November 2021 to February 2022, a total of 500 car-owning families who visited or were hospitalized in the department of pediatrics of our hospital were surveyed by self-filling questionnaire method. Through the investigation of personal situation, family situation, travel habits, use of child safety seat, cognition of safe riding, etc.

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Background: Prognostic assessment for colorectal cancer (CRC) displays substantial heterogeneity, as reliance solely on traditional TNM staging falls short of achieving precise individualized predictions. The integration of diverse biological information sources holds the potential to enhance prognostic accuracy.

Objective: To establish a comprehensive multi-tiered precision prognostic evaluation system for CRC by amalgamating gene expression profiles, clinical characteristics, and tumor microsatellite instability (MSI) status in CRC patients.

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The study explored the impact of pretreatment serum albumin-to-alkaline phosphatase ratio (AAPR) and changes in tumor blood supply on pathological complete response (pCR) in breast cancer (BC) patients following neoadjuvant chemotherapy (NACT). Additionally, a nomogram for predicting pCR was established and validated. The study included BC patients undergoing NACT at Yongchuan Hospital of Chongqing Medical University from January 2019 to October 2023.

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