1,431 results match your criteria: "The Nippon Dental University.[Affiliation]"

Automated design prediction for definitive obturator prostheses: A case-based reasoning study.

J Prosthodont

January 2025

Department of Advanced Prosthodontics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Purpose: This study aims to evaluate the effectiveness of a case-based reasoning (CBR) system in predicting the design of definitive obturator prostheses for maxillectomy patients.

Materials And Methods: Data from 209 maxillectomy cases, including extraoral images of obturator prostheses and occlusal images of maxillectomy defects, were collected from Institute of Science Tokyo Hospital. These cases were organized into a structured database using Python's pandas library.

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  • The study examined the types of bacteria found on finger skin before and after cleaning with ethanol, and compared them to the bacteria on smartphone touchscreens.
  • The results showed that the bacteria levels on smartphones were low, similar to the levels found on fingers after they were disinfected with ethanol.
  • Ethanol disinfection significantly decreased the number of bacteria on the fingers, reducing it to about 1/13 of the original amount.
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Effect of geometry on clasp retention force: a finite element analysis study.

BMC Oral Health

December 2024

Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, 246 Yangqiao Zhong Road, Fuzhou, Fujian, 350002, PR China.

Purpose: The retention force of a realistic clasp is influenced by multiple, interrelated factors, which complicates the identification of the fundamental relationship between clasp geometry and retention force. While realistic clasps exhibit various shapes, they share basic geometric elements such as length, diameter, and curvature. Simpler geometries are often more conducive to identifying the underlying issues.

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Prevalence of suspected anemia in Japanese young children determined using non-invasive hemoglobin measurements: an observational study.

Biosci Biotechnol Biochem

December 2024

Department of Nutrition and Health, Faculty of Nutritional Sciences, Sagami Women's University, 2-1-1 Bunkyo, Minami-ku, Sagamihara, Kanagawa, Japan.

Recently, non-invasive hemoglobin measurement (SpHb) using Pulse CO-Oximeter Rad-67™ Spot-check (Rad-67) has been validated although anemia diagnosis typically relies on blood hemoglobin concentration measurement. In this large-scale survey of Japanese children aged 1-5 years, we evaluated SpHb distribution to understand the prevalence of suspected anemia, and further examined the relationship between SpHb and background factors. Children were recruited from large retail stores in Japan between November 2022 and August 2023.

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Background: Erythroid cells contribute to embryonic organ development and adult tissue repair supplying oxygen to tissues. During mouse development, the primitive erythroid cells produced in the extraembryonic blood islands of the yolk sac begin to circulate as immature and nucleated erythroblasts with the onset of cardiac contractions around embryonic day 9.5 (E9.

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Orbital defects can result from a myriad of underlying diseases and injuries. Treatment of malignant neoplasms and maxillofacial trauma are common reasons for orbital exenteration. Recently, a growing number of cases of orbital defects have been reported due to mucormycosis in patients with COVID-19.

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The objective of this study was to investigate the feasibility of using a cost-effective desktop three-dimensional (3D) fused deposition modeling (FDM) printer to fabricate dental casts to overcome the problems of conventional dental plaster casts, such as fragility and low portability. First, a 3D computer-aided design (CAD) model of the dental cast was prepared in the Standard Triangle Language (STL) format. Twelve 3D models were fabricated using a desktop FDM 3D printer under different 3D printing parameters/conditions, including shape, placement direction, and infill percentage.

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Enamel microcracks are often apparent in the teeth of elderly individuals. However, accurate clinical diagnosis of enamel microcracks is very difficult. The purpose of this study was to examine the utility of inspections for enamel microcracks using a near-infrared light transillumination device with fluorescence staining.

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  • Aerobic exercise habits have shown promise in reducing inflammation and may help suppress atherosclerosis progression by increasing the albumin-globulin ratio (AGR), which is a key immune-inflammatory indicator.
  • A study involving 8,381 participants found that those who engaged in regular aerobic exercise had a significantly higher AGR and lower levels of certain immune-inflammatory markers compared to those who did not exercise.
  • The research suggests that the beneficial effects of aerobic exercise on AGR might be mediated by a reduction in immune-inflammatory markers, potentially lowering the risk for atherosclerotic cardiovascular disease.
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Introduction: Cigarette smoking is a significant risk factor for atherosclerotic cardiovascular diseases (ASCVDs). Mildly elevated total serum bilirubin (TSB) levels can exert anti-atherosclerotic effects and may regulate inflammation. We explore the relationship between TSB levels, smoking, and inflammation.

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Digitization of Dentate and Edentulous Maxillectomy and Mandibulectomy Defects with Three Different Intraoral Scanners: A Comparative In Vitro Study.

J Clin Med

November 2024

Department of Advanced Prosthodontics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan.

: The objective of this study was to compare the trueness and precision of three intraoral scanners (IOSs) for the digitization of dentate and edentulous maxillectomy and mandibulectomy defects in artificial models. Four representative defect models-a dentate and an edentulous maxillectomy model and a dentate and an edentulous mandibulectomy model-were used for digital scanning. After a reference scan of each model, they were scanned with three IOSs: CEREC AC Omnicam, True Definition, and cara TRIOS 3.

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Aim: Diabetes is a significant risk factor that exacerbates the pathological progression of periodontal disease. In recent years, attention has focused on the effect of regulatory T cells (Tregs), which play a central role in immune tolerance, on inflammatory processes in periodontal tissue, suggesting a link with diabetes-associated periodontitis. In this study, we examined the dynamics of Tregs in periodontal tissue of mice with streptozotocin (STZ)-induced hyperglycemia.

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  • * Case 2 features a 53-year-old woman with left breast cancer, diagnosed with Stage I early-stage solid-tubular carcinoma, characterized as ER-positive, PgR-positive, HER2-negative, and a Ki-67 index of 24%.
  • * Both patients were deemed at intermediate risk for recurrence and were treated with a combination of S-1 and endocrine therapy, which may
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We report encapsulated papillary carcinoma and mucinous carcinoma in a case of local advanced bilateral breast cancer. The patient was 78-year-old woman who had bilateral breast tumor. The right palpable tumor was 6 cm in diameter and left tumor was 7 cm in a diameter.

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Purpose: This study aimed to investigate the relationships between reference planes and oral functions on the habitual and non-habitual chewing sides.

Materials And Methods: Thirty-four subjects with no abnormalities in the maxillofacial region and oral functions were enrolled in this study. Relationships between angles between the reference plane (Frankfort horizontal plane, Camper's plane, and occlusal plane) and masticatory performance, occlusal force, and occlusal contact area by chewing side were examined.

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Correction: Studies on the antifungal effects of Hinokitiol on Candida albicans: inhibition of germ tube formation and synergistic pharmacological effects of miconazole.

Odontology

November 2024

Course of Clinical Science, Field of Oral and Maxillofacial Surgery and Systemic Medicine, Oral and Maxillofacial Surgery, Graduate School of Life Dentistry at Niigata, The Nippon Dental University, 1-8 Hamaura-cho, Chuo-ku, Niigata, 951-8580, Japan.

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Background/aim: The therapeutic efficacy of the paclitaxel (PTX) + cetuximab (Cmab) combination regimen was investigated in patients with recurrence or metastasis after superselective intraarterial chemoradiotherapy (SSIACRT) for oral cancer, and the safety was retrospectively examined.

Patients And Methods: All enrolled patients with advanced oral cancer or who had refused surgery over 10 years from December 2012 to December 2022 underwent SSIACRT for 6 to 9 weeks [cisplatin (CDDP): total 160-630 mg/m and radiotherapy: total 50-70 Gy]. Nine cases (tongue cancer, maxillary gingival cancer, and mandibular gingival cancer; three cases each) were subjected to PTX + Cmab therapy.

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In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin.

Tissue Eng Regen Med

December 2024

Department of Oral and Maxillofacial Surgery, School of Life Dentistry at Tokyo, The Nippon Dental University, 1-9-20, Fujimi, Chiyoda-ku, Tokyo, 102-8159, Japan.

Background: Injectable platelet-rich fibrin (iPRF), a liquid form of PRF that is prepared from peripheral blood without anticoagulants, promotes tissue wound healing and regeneration. The present study focused on iPRF-like bone marrow aspirate concentrate (iBMAC) prepared without anticoagulant, and the regenerative potential of iPRF and iBMAC was compared in vitro.

Methods: iPRF and iBMAC were prepared from the same New Zealand white rabbits.

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Objectives: This longitudinal text-mining study examines dental hygiene students' perceptions of dental hygienists and dentists at three different points in time during their training course. The null hypothesis of the study was that there would be no change in the dental hygiene students' perceptions of the dental hygienists and dentists over the course of 3 years.

Materials And Methods: First-year dental hygiene students participated in this study beginning with the academic year 2020.

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3D printing is increasingly used in dentistry, with biocompatible resins playing a key role. This study compared the radioprotective properties of a commonly used 3D-printed resin (Formlabs surgical guide resin) with traditional heat-cured resin and examined the relationship between material thickness and radiation attenuation. The specimens consisted of 3D-printed and heat-cured resin specimens, each measuring 45 × 45 mm, with five different thicknesses (6, 8, 10, 12, and 14 mm), totaling 100 samples.

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  • The study examined joint effusion in patients with temporomandibular disorders (TMDs) that involved disc displacement, using MRI images of 97 temporomandibular joints (TMJs).
  • Of the TMJs evaluated, joint effusion was observed in 70 cases, primarily in the superior articular cavity, and the presence of myofascial or TMJ pain did not affect the occurrence of effusion.
  • The findings indicated that joint effusion is more prevalent in cases of disc displacement without reduction and that the volume of synovial fluid in effusions was unaffected by the presence of pain.
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(1) Background: Diet is significant for nutritional intake and serves as an essential element for improving quality of life (QOL). Poor dietary management skills increase the risk of onset or progression of lifestyle-related diseases, and, in particular, are a factor in reduced QOL during old age. This study aimed to clarify the physical and social background factors impeding dietary self-management.

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Objectives: This study aimed to clarify the effect of metal elements in the coloring liquids used in the infiltration method on the physical properties of zirconia.

Methods: Two types of zirconia discs 5Y-PSZ (SHOFU Disc ZR Lucent FA, SHOFU, Kyoto, Japan) were used: with monolayer shades from W2 to W3 (Pearl White) and 5Y-PSZ with multilayer shades from A3 to A4 (L). Five kinds of coloring liquid were used to infiltrate into semi-sintered Pearl White (T-glass [CT], A4 [CA], White-Opaque [CW], Gingiva 1 [CG], and Blue X [CB]).

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Maximum standardized uptake value for parotid and submandibular glands in patients with Sjögren's syndrome and submandibular sialolithiasis using salivary gland SPECT/CT.

Odontology

October 2024

Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, 1-8 Hamaura-Cho, Chuo-Ku, Niigata, Niigata, 951-8580, Japan.

Article Synopsis
  • SPECT/CT imaging is utilized to evaluate lesions in the head and neck, specifically looking at the salivary glands in patients with Sjögren's syndrome and submandibular sialolithiasis.
  • A study involving 45 patients revealed that maximum standardized uptake values (SUVs) for salivary glands were significantly lower in those with Sjögren's syndrome compared to those with sialolithiasis, indicating impaired gland function.
  • The findings suggest that SPECT/CT can be an effective tool for assessing salivary gland health and function in these patient groups, aiding in clinical management.
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[Purpose] Using new diagnostic criteria, this study aimed to clarify the relationship between respiratory sarcopenia and respiratory muscle weakness in community-dwelling older adults. [Participants and Methods] Basic information, body composition, motor function, respiratory function, and respiratory muscle strength were analyzed for 43 elderly community residents who participated in a health promotion program between 2021 and 2023. Respiratory sarcopenia and respiratory muscle weakness were evaluated based on maximal intraoral pressure and skeletal muscle index.

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