5 results match your criteria: "The Netherlands. r.offringa@biology.leidenuniv.nl.[Affiliation]"
PDK1 regulates auxin transport and Arabidopsis vascular development through AGC1 kinase PAX.
Nat Plants
May 2020
Plant Developmental Genetics, Institute of Biology Leiden, Leiden University, Leiden, the Netherlands.
Article Synopsis
- PDK1 is a key regulator of AGC kinases in eukaryotes, and its loss leads to serious developmental issues in plants, unlike the lethal consequences seen in animals and yeasts.
- Using CRISPR/Cas9 technology, researchers created true loss-of-function pdk1 mutations in Arabidopsis, which revealed severe defects such as fused cotyledons and impaired root growth.
- PDK1 activates the AGC1 kinase PAX through phosphorylation to regulate polar auxin transport, a fundamental process in plant development.
A suppressor of axillary meristem maturation promotes longevity in flowering plants.
Nat Plants
April 2020
Plant Developmental Genetics, Institute of Biology Leiden, Leiden University, Leiden, the Netherlands.
Post-embryonic development and longevity of flowering plants are, for a large part, determined by the activity and maturation state of stem cell niches formed in the axils of leaves, the so-called axillary meristems (AMs). The genes that are associated with AM maturation and underlie the differences between monocarpic (reproduce once and die) annual and the longer-lived polycarpic (reproduce more than once) perennial plants are still largely unknown. Here we identify a new role for the Arabidopsis AT-HOOK MOTIF NUCLEAR LOCALIZED 15 (AHL15) gene as a suppressor of AM maturation.
View Article and Find Full Text PDFModelling the dynamics of polar auxin transport in inflorescence stems of Arabidopsis thaliana.
J Exp Bot
February 2016
Plant Biodynamics Laboratory, Institute of Biology Leiden, Leiden University, 2333 EB Leiden, The Netherlands Department of Molecular and Developmental Genetics, Institute of Biology Leiden, Leiden University, 2333 EB Leiden, The Netherlands
The polar transport of the plant hormone auxin has been the subject of many studies, several involving mathematical modelling. Unfortunately, most of these models have not been experimentally verified. Here we present experimental measurements of long-distance polar auxin transport (PAT) in segments of inflorescence stems of Arabidopsis thaliana together with a descriptive mathematical model that was developed from these data.
View Article and Find Full Text PDFPlasma membrane-bound AGC3 kinases phosphorylate PIN auxin carriers at TPRXS(N/S) motifs to direct apical PIN recycling.
Development
July 2015
Molecular and Developmental Genetics, Institute Biology Leiden, Leiden University, Sylvius Laboratory, Sylviusweg 72, 2333BE Leiden, The Netherlands.
Cell polarity and development.
J Integr Plant Biol
September 2013
Molecular and Developmental Genetics, Institute Biology Leiden, Leiden University, Sylvius Laboratory, Sylviusweg 72, 2333, BE, The Netherlands.