3 results match your criteria: "The Netherlands. l.eijssen@maastrichtuniversity.nl[Affiliation]"
BMC Bioinformatics
August 2015
Department of Bioinformatics - BiGCaT, Maastricht University, P.O. Box 616, UNS 50 Box 19, 6200, MD, Maastricht, The Netherlands.
Background: Biological pathways are descriptive diagrams of biological processes widely used for functional analysis of differentially expressed genes or proteins. Primary data analysis, such as quality control, normalisation, and statistical analysis, is often performed in scripting languages like R, Perl, and Python. Subsequent pathway analysis is usually performed using dedicated external applications.
View Article and Find Full Text PDFBMC Genomics
June 2015
TNO, Research Group Microbiology & Systems Biology, Utrechtseweg 48, 3704 HE, Zeist, The Netherlands.
Background: Illumina whole-genome expression bead arrays are a widely used platform for transcriptomics. Most of the tools available for the analysis of the resulting data are not easily applicable by less experienced users. ArrayAnalysis.
View Article and Find Full Text PDFNucleic Acids Res
July 2013
Department of Bioinformatics-BiGCaT, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.
Quality control (QC) is crucial for any scientific method producing data. Applying adequate QC introduces new challenges in the genomics field where large amounts of data are produced with complex technologies. For DNA microarrays, specific algorithms for QC and pre-processing including normalization have been developed by the scientific community, especially for expression chips of the Affymetrix platform.
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