1 results match your criteria: "The Netherlands. i.michon@chem.leidenuniv.nl[Affiliation]"
The effect of TGF-beta receptor binding peptides on smooth muscle cells.
Biochem Biophys Res Commun
May 2002
Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands.
TGF-beta1 is a potent regulator of vascular smooth muscle cell (VSMC) proliferation, migration, and extracellular matrix (ECM) synthesis. In this study, we selected two peptides, IM-1 and IM-2, that bind to the TGF-beta type II receptor (TGF-beta RII) using phage display. IM-1 and IM-2 bind to the TGF-beta RII, with a K(d) of 1 microM.
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