1 results match your criteria: "The Netherlands. Electronic address: m.r.nejadnik@lacdr.leidenuniv.nl.[Affiliation]"
No Touching! Abrasion of Adsorbed Protein Is the Root Cause of Subvisible Particle Formation During Stirring.
J Pharm Sci
February 2016
Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, 2300 RA, The Netherlands. Electronic address:
This study addressed the effect of contact sliding during stirring of a monoclonal antibody solution on protein aggregation, in particular, in the nanometer and micrometer size range. An overhead stirring set-up was designed in which the presence and magnitude of the contact between the stir bar and the container could be manipulated. A solution of 0.
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