2 results match your criteria: "The Netherlands. Electronic address: f.vanleeuwen@maastrichtuniversity.nl.[Affiliation]"
The next steps in curing Alzheimer's disease.
Prog Mol Biol Transl Sci
July 2020
Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands. Electronic address:
The Alzheimer's disease (AD) field urgently needs new ideas. I offer here a number of thoughts focusing on the combination of the cellular phase of AD and new bionic techniques. These techniques enable to answer alternative hypotheses raised and help to unravel the multifactorial mechanisms initiating Alzheimer's disease.
View Article and Find Full Text PDFParadoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model.
Neurobiol Aging
December 2018
Department of Psychiatry and Neuropsychology, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands. Electronic address:
Amyloid-β (Aβ) plaques are a prominent pathological hallmark of Alzheimer's disease (AD). They consist of aggregated Aβ peptides, which are generated through sequential proteolytic processing of the transmembrane protein amyloid precursor protein (APP) and several Aβ-associated factors. Efficient clearance of Aβ from the brain is thought to be important to prevent the development and progression of AD.
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