687,632 results match your criteria: "The Netherlands; and Lymphoma and Myeloma Center Amsterdam[Affiliation]"

Background: Psychologists play a crucial role in providing essential psychological aid to individuals navigating the challenges posed by the COVID-19 pandemic. However, studies focusing on the mental health of psychologists during the COVID-19 pandemic remain scarce. This study investigates the interaction between coping strategies and psychological distress among a group of Indonesian psychologists.

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Measuring implicit associations with behaviours to improve resident mood: development of implicit association tasks for nursing home care providers.

Int J Nurs Stud Adv

June 2025

Department of Primary and Community Care, Radboud University Medical Center, Research Institute for Medical Innovation, Radboudumc Alzheimer Center, Geert Grooteplein 21, 6525 EZ Nijmegen, the Netherlands.

Objective: To develop and evaluate instruments for measuring implicit associations of nursing home care providers with behaviours aimed at improving resident mood.

Method: Study 1 ( = 41) followed an iterative approach to develop two implicit association tasks measuring implicit attitude (positive versus negative valence) and motivation (wanting versus not wanting) regarding mood-improving behaviours, followed by an evaluation of the content validity for target stimuli representing these behaviours. In Study 2 ( = 230), the tasks were assessed for stimulus classification ease (accuracy and speed) and internal consistency.

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Introduction: Remyelination of demyelinated axons can occur as an endogenous repair mechanism in multiple sclerosis (MS), but its efficacy varies between both MS individuals and lesions. The molecular and cellular mechanisms that drive remyelination remain poorly understood. Here, we studied the relation between microglia activation and remyelination activity in MS.

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Introduction: Bryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies. In HIV research, it has shown anti-HIV effects during acute infection and reactivation of latent HIV in chronic infection. As effective CD8+ T cell responses are essential for eliminating reactivated virus and achieving a cure, it is important to investigate how bryostatin-1 affects HIV-specific CD8+ T cells.

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Position in proton Bragg curve influences DNA damage complexity and survival in head and neck cancer cells.

Clin Transl Radiat Oncol

March 2025

Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.

Background And Purpose: Understanding the cellular and molecular effect of proton radiation, particularly the increased DNA damage complexity at the distal end of the Bragg curve, is current topic of investigation. This work aims to study clonogenic survival and DNA damage foci kinetics of a head and neck squamous cell carcinoma cell line at various positions along a double passively scattered Bragg curve. Complementary studies are conducted to gain insights into the link between cell survival variations, experimentally yielded foci and the number and complexity of double strand breaks (DSBs).

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Background: Heart Failure (HF) quality of care (QoC) is associated with clinical outcomes. Therefore, we investigated differences in HF QoC across worldwide regions (with differing national income) and the association of quality indicators with outcomes.

Methods: We examined the quality of care (QoC) in acute heart failure (HF) patients across different regions using quality indicators (QIs) from the European Society of Cardiology (ESC) and the American Heart Association (AHA) to evaluate QoC.

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Indigestible gut permeability markers are used to assess gut integrity and can be administered to calves via a milk meal (MM) or orally pulsed (OP). This study investigated how marker administration route (ADM_R) affects the estimation of gut permeability in relation to milk replacer (MR) fat inclusion. Thirty-two newborn Holstein calves were blocked based on their arrival sequence at the facility.

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Globally, many complex issues, like the ageing population and health inequalities, require attention. People are experimenting to combat these issues in their local contexts through bigger or smaller networks; however, much of the knowledge about these initiatives remains localised and elitist and omits the voices and perspectives of citizens. This article identifies the characteristics of a more horizontal, emergent and plural epistemology to mobilize knowledge.

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Previous studies have shown that perceptual performance can be modulated at specific frequencies phase-locked to self-paced motor actions, but findings have been inconsistent. To investigate this effect at the population level, we tested 50 participants who performed a self-paced button press followed by a threshold-level detection task, using both fixed- and random-effects analyses. Contrary to expectations, the aggregated data showed no significant action-related modulation.

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The changing social structure of housing tenures through China's successive urban housing reforms.

Hous Stud

March 2024

Department of Geography, Planning and International Development Studies, University of Amsterdam, Amsterdam, Netherlands.

Housing system transitions often involve successive but overlapping periods of reform with crucial implications for housing inequality dynamics. Building on welfare regime and market transition discussions, this paper considers how the shifting roles of the state, market, and family in housing provision in China have led to changing housing tenures and differentiated access to them between populations with varying socio-economic resources. Drawing on two national datasets, our analyses reveal that the four decades of reforms dramatically upended urban China's tenure structure with market homeownership becoming the dominant tenure.

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Humic acid (HA) enhances colloidal transport in porous media, yet the mechanisms by which the HA adsorption conformation affects colloid transport remain unclear. This study investigated the influence of HA on the transport of petroleum-hydrocarbon-contaminated soil colloids (TPHs-SC) in saturated sand columns. The presence of TPHs on the colloidal surface occupied adsorption sites, hindering HA from forming a horizontal adsorption conformation, as observed on uncontaminated soil colloids (SC).

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Vocalizations play a crucial role in the social systems of many animals and may inadvertently reveal behavioural characteristics of the sender. Bats, the second largest mammalian order, rely extensively on vocalizations owing to their nocturnal lifestyle and complex social systems, making them ideal for studying links between vocalizations and consistent behavioural traits. In this study, we developed a new testing regime to investigate whether consistent individual vocalization differences in nectarivorous bats are associated with specific behavioural types.

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To forecast how fast populations can adapt to climate change, it is essential to determine the evolutionary potential of different life-cycle stages under selection. In birds, timing of gonadal development and moult are primarily regulated by photoperiod, while laying date is highly phenotypically plastic to temperature. We tested whether geographic variation in phenology of these life-cycle events between populations of great tits () has a genetic basis, indicating that contemporary genetic adaptation is possible.

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The promise of community-driven preprints in ecology and evolution.

Proc Biol Sci

January 2025

Evolution and Ecology Research Centre, School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia.

Publishing preprints is quickly becoming commonplace in ecology and evolutionary biology. Preprints can facilitate the rapid sharing of scientific knowledge establishing precedence and enabling feedback from the research community before peer review. Yet, significant barriers to preprint use exist, including language barriers, a lack of understanding about the benefits of preprints and a lack of diversity in the types of research outputs accepted (e.

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Background: We evaluated UK nurses' preferences for pediatric hexavalent vaccine attributes.

Research Design And Methods: In a discrete-choice experiment study, 150 nurses chose between 2 hypothetical pediatric hexavalent vaccines with varying attribute levels (device type, plastic in packaging, time on the market, and time the vaccine can stay safely at room temperature) in a series of choice questions. Using random-parameters logit-model estimates, conditional relative attribute importance (CRAI) and odds ratios (ORs) were calculated.

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For the computational design of new polymeric materials, accurate methods for determining the glass transition temperature () are required. We apply an ensemble approach in molecular dynamics (MD) and examine its predictions of and their associated uncertainty. We separate the uncertainty into the aleatoric contributions arising from dynamical chaos and that due to the computational scenarios chosen to compute .

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Context-specific eQTLs provide deeper insight into causal genes underlying shared genetic architecture of critically ill COVID-19 and idiopathic pulmonary fibrosis.

HGG Adv

January 2025

Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA; University Program in Genetics and Genomics, Duke University, Durham, NC, USA; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC, USA. Electronic address:

Most genetic variants identified through genome-wide association studies (GWAS) are suspected to be regulatory in nature, but only a small fraction colocalize with expression quantitative trait loci (eQTLs, variants associated with expression of a gene). Therefore, it is hypothesized but largely untested that integration of disease GWAS with context-specific eQTLs will reveal the underlying genes driving disease associations. We used colocalization and transcriptomic analyses to identify shared genetic variants and likely causal genes associated with critically ill COVID-19 and idiopathic pulmonary fibrosis.

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Targeted metagenomics is a rapidly expanding technology to analyze complex biological samples and genetic monitoring of environmental samples. In this research field, data analytical aspects play a crucial role. In order to teach targeted metagenomics data analysis, we developed a 4-week inquiry-driven modular course-based undergraduate research experience (mCURE) using publicly available Australian coral microbiome DNA sequencing data and associated metadata.

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Daprodustat, a novel oral hypoxia-inducible factor prolyl hydroxylase inhibitor is approved in the United States for the treatment of anemia due to chronic kidney disease (CKD) in adults receiving dialysis for at least 4 months. Pharmacodynamic dose-hemoglobin (Dose-Hgb) models were developed as daprodustat progressed through development. To support global phase III development, a dose-titration algorithm, guided by simulations from the initial Dose-Hgb model based on phase II clinical data, was implemented.

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Gliomas are highly heterogeneous and often include a nonenhancing component that is hyperintense on T weighted MRI. This can often not be distinguished from secondary gliosis and surrounding edema. We hypothesized that the extent of these T hyperintense areas can more accurately be determined on high-quality 7 T MRI scans.

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Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD. A total of 278 de novo PD patients (ICD-free at enrollment) were selected from the Parkinson's Progression Markers Initiative database.

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Cultural differences in diagnosis and treatment perceptions: Turkish collectivistic representations of common mental disorders.

Int J Qual Stud Health Well-being

December 2025

Department of Language and Communication, Centre for Language Studies, Radboud University, Nijmegen, The Netherlands.

Purpose: Attention-deficit/hyperactivity disorder (ADHD) is less diagnosed among Turkish children, and Turkish clients drop out more often from depression treatments than Dutch clients. This article proposes that cultural differences in collectivistic versus individualistic perceptions of getting an ADHD diagnosis and being treated for depression might explain these ethnic disparities, which have been explored in this study.

Methods: Nine focus group discussions with Turkish individuals and 18 interviews with primary mental health practitioners were conducted.

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Background: Many studies have found more severe COVID-19 outcomes in migrants and ethnic minorities throughout the COVID-19 pandemic, while recent evidence also suggests higher risk of longer-term consequences. We studied the risk of a long COVID diagnosis among adult residents in Sweden, dependent on country of birth and accounting for known risk factors for long COVID.

Methods: We used linked Swedish administrative registers between March 1, 2020 and April 1, 2023, to estimate the risk of a long COVID diagnosis in the adult population that had a confirmed COVID-19 infection.

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Background: Fatigue and inactivity are linked to decreased health-related quality of life (HRQoL) in chronic conditions. A multidimensional approach to activity pacing may improve HRQoL by promoting physical activity (PA) and alleviating fatigue. Addressing fatigue across chronic conditions is crucial, especially when underlying causes are unknown.

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